PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

TALE

Protein Properties

Length: 329aa MW: 37012.6 Da PI: 4.6633

Description

TALE family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa14g030660.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	26.7	9.6e-09	271	305	21	55
HSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS Homeobox 21 knrypsaeereeLAkklgLterqVkvWFqNrRake 55 k +yp++ ++ LA+ +gL+++q+ +WF N+R ++ Csa14g030660.1 271 KWPYPTEGDKIALADATGLDQKQINNWFINQRKRH 305 669*****************************885 PP
2	ELK	30.1	1.1e-10	225	246	1	22
ELK 1 ELKhqLlrKYsgyLgsLkqEFs 22 +LK++LlrK++++++sLk EFs Csa14g030660.1 225 DLKDRLLRKFGSRISSLKLEFS 246 69*******************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM01255	2.3E-22	83	127	IPR005540	KNOX1
Pfam	PF03790	4.8E-21	85	126	IPR005540	KNOX1
SMART	SM01256	3.3E-26	134	185	IPR005541	KNOX2
Pfam	PF03791	1.8E-24	138	184	IPR005541	KNOX2
SMART	SM01188	6.3E-5	225	246	IPR005539	ELK domain
Pfam	PF03789	2.6E-7	225	246	IPR005539	ELK domain
PROSITE profile	PS51213	9.83	225	245	IPR005539	ELK domain
PROSITE profile	PS50071	12.341	245	308	IPR001356	Homeobox domain
SuperFamily	SSF46689	2.4E-19	246	321	IPR009057	Homeodomain-like
SMART	SM00389	1.9E-12	247	312	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	2.8E-27	250	309	IPR009057	Homeodomain-like
CDD	cd00086	1.00E-11	254	309	No hit	No description
Pfam	PF05920	4.8E-17	265	304	IPR008422	Homeobox KN domain
PROSITE pattern	PS00027	0	283	306	IPR017970	Homeobox, conserved site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010073	Biological Process	meristem maintenance
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 329 aa Download sequence Send to blast
MDGVYNFHSA GDYTDKAVLM MSPEILMFPS DYQALLCSSA GENRVSDVFG SDELLSAAAS 60 ALSSEAASIA PEIRRNDDNV SLSVIKTKIA CHPSYPRLLQ AYIDCQKVGA PPEIACLLEE 120 IQRESDVYKR DVVPLSCYGA DPELDEFMET YCDILVKYKS DLARPFDEAT SFLNKIEMQL 180 RNLCTGVDSA RNNVSEDGAI SSDEELSGGD HEVAEDGKQR CEDRDLKDRL LRKFGSRISS 240 LKLEFSKKKK KGKLPREARQ ALLDWWNLHY KWPYPTEGDK IALADATGLD QKQINNWFIN 300 QRKRHWKPSE NMPFAMMDDS SGSFFTEE*

Functional Description ? help Back to Top
Source	Description
UniProt	Plays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269\|PubMed:16798887}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa14g030660.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269\|PubMed:11311158, ECO:0000269\|PubMed:16798887}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT002930	0.0	BT002930.1 Arabidopsis thaliana clone RAFL14-89-I21 (R20256) putative homeodomain transcription factor KNAT6 (At1g23380) mRNA, complete cds.
GenBank	BT004370	0.0	BT004370.1 Arabidopsis thaliana clone U20256 putative homeodomain transcription factor KNAT6 (At1g23380) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010460124.1	0.0	PREDICTED: homeobox protein knotted-1-like 6 isoform X1
Swissprot	Q84JS6	0.0	KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBL	D7KNF2	0.0	D7KNF2_ARALL; Uncharacterized protein
STRING	XP_010460124.1	0.0	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM835	27	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G23380.1	0.0	KNOTTED1-like homeobox gene 6

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Khan M, et al. Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis. Plant Physiol., 2015. 169(3): p. 2166-86 [PMID:26417006]