PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Csa13g025680.1
Organism
Camelina sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina
Family E2F/DP
Protein Properties Length: 475aa    MW: 51775.3 Da    PI: 4.4785
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Csa13g025680.1genomeCSGPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.52e-27135200171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liek+ kn+i+wkg
  Csa13g025680.1 135 RYDSSLGLLTKKFINLIKQAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIQWKG 200
                     6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.9E-29132202IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013725.9E-35135200IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.72E-17135198IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.6E-24137200IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.04E-44211317No hitNo description
SuperFamilySSF1440741.7E-31212317No hitNo description
PfamPF164211.5E-31216315IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 475 aa     Download sequence    Send to blast
MSEEPQQFPP SKRQYHPSLS SMKPPLVAPG EYHRFDSAET RLAGGGAAPS AAAADHAVSD  60
SIVIKSTLKR KTDAVNQISE PNELSTCVLQ TPVSGKGGKA KKTSRSAKSN KSGTLASGSN  120
AGSPGSNFAQ AGTCRYDSSL GLLTKKFINL IKQAEDGILD LNKAADTLEV QKRRIYDITN  180
VLEGIGLIEK TLKNRIQWKG LDVSKPGETI ENIANLQDEV RNLTVEEAKL DDQIRESQDR  240
LTSLSEDENN KRLLFVTEDD IKNLPCFQNK TLIAVKAPHG TTLEVPDPDE AGGYSQRRYR  300
IILRSTMGPI DVYLVSQFEE SFEDIPHADE PSNAPDVPSS VPDEPSNLPS TSGLPENHDV  360
AMPMEEDSTG RKMDIQELDD TQRVYSDIES HDFVDGIMKI VPPDLDMGVD YWLRSEVGEV  420
SITDLWPDES GPDWNHMGSF DQNHAGPSNT TLEQPQTPSS PTPEDSTATR STGS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A9e-25135201774PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapCsa13g025680.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAJ2945330.0AJ294533.1 Arabidopsis thaliana mRNA for E2F-related protein (e2Fb gene).
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010454484.10.0PREDICTED: transcription factor E2FB-like isoform X1
RefseqXP_010454485.10.0PREDICTED: transcription factor E2FB-like isoform X2
SwissprotQ9FV710.0E2FB_ARATH; Transcription factor E2FB
TrEMBLR0FJU80.0R0FJU8_9BRAS; Uncharacterized protein
STRINGXP_010454485.10.0(Camelina sativa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.20.0E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]