PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

Dof

Protein Properties

Length: 422aa MW: 45252.3 Da PI: 8.5445

Description

Dof family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa11g099790.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-Dof	123.9	5.3e-39	120	179	3	62
zf-Dof 3 ekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkkss 62 ++ +kcprC+st+tkfCyynnyslsqPryfCk+CrryWtkGG+lrn+PvGgg+rknkk s Csa11g099790.1 120 DHPQKCPRCESTHTKFCYYNNYSLSQPRYFCKTCRRYWTKGGTLRNIPVGGGCRKNKKPS 179 6789*****************************************************976 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
ProDom	PD007478	7.0E-35	108	173	IPR003851	Zinc finger, Dof-type
Pfam	PF02701	1.4E-32	121	177	IPR003851	Zinc finger, Dof-type
PROSITE profile	PS50884	28.761	123	177	IPR003851	Zinc finger, Dof-type
PROSITE pattern	PS01361	0	125	161	IPR003851	Zinc finger, Dof-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010067	Biological Process	procambium histogenesis
GO:0010087	Biological Process	phloem or xylem histogenesis
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 422 aa Download sequence Send to blast
LIHIPTPKLL LAFSSHFSSP PSPSLSLDFV QQLLLKFSLS PKLNNQTKHK MGLTSLQVCM 60 DSDWLQEAES SGGSMLDSST TSPSAADILA ACSTRPQASA VAVAAAALMD GGRRLRPPHD 120 HPQKCPRCES THTKFCYYNN YSLSQPRYFC KTCRRYWTKG GTLRNIPVGG GCRKNKKPSS 180 SNSSSSTSSG KKPSNIITTN TTDLMALAHS HQNYQTSPLG FSHFGGLMGS YSTPEHSNVG 240 FLESKYGGLL SQSPRPIDFL DSKFDLMGVN NDNLVMVDHG SNGDHHHHHN NHHMGLHHGL 300 GLNNNNGGFN GISPGSNGNG GGLMDISACQ RLMLSSYDHQ HYNHQEDHQR VTTITDVKPN 360 PKLLSLDWQQ DQCYSNGGGN GGVGKSDGGG YGGGGYINGL GSSWNGLMNG YGSSTKTNSL 420 V*

Sequence ? help Back to Top

Protein Sequence Length: 422 aa Download sequence Send to blast

LIHIPTPKLL LAFSSHFSSP PSPSLSLDFV QQLLLKFSLS PKLNNQTKHK MGLTSLQVCM  60
DSDWLQEAES SGGSMLDSST TSPSAADILA ACSTRPQASA VAVAAAALMD GGRRLRPPHD  120
HPQKCPRCES THTKFCYYNN YSLSQPRYFC KTCRRYWTKG GTLRNIPVGG GCRKNKKPSS  180
SNSSSSTSSG KKPSNIITTN TTDLMALAHS HQNYQTSPLG FSHFGGLMGS YSTPEHSNVG  240
FLESKYGGLL SQSPRPIDFL DSKFDLMGVN NDNLVMVDHG SNGDHHHHHN NHHMGLHHGL  300
GLNNNNGGFN GISPGSNGNG GGLMDISACQ RLMLSSYDHQ HYNHQEDHQR VTTITDVKPN  360
PKLLSLDWQQ DQCYSNGGGN GGVGKSDGGG YGGGGYINGL GSSWNGLMNG YGSSTKTNSL  420
V*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Promotes expression (PubMed:19915089). The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements (PubMed:30626969). Involved in the regulation of interfascicular cambium formation and vascular tissue development, particularly at a very early stage during inflorescence stem development; promotes both cambium activity and phloem specification, but prevents xylem specification (PubMed:19915089). {ECO:0000250\|UniProtKB:Q9M2U1, ECO:0000269\|PubMed:19915089, ECO:0000269\|PubMed:30626969}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00580	DAP	Transfer from AT5G62940	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa11g099790.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK228992	0.0	AK228992.1 Arabidopsis thaliana mRNA for Dof zinc finger protein - like, complete cds, clone: RAFL16-29-O12.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010444159.1	0.0	PREDICTED: dof zinc finger protein DOF5.6-like
Swissprot	Q9FM03	1e-180	DOF56_ARATH; Dof zinc finger protein DOF5.6
TrEMBL	D7MNC9	0.0	D7MNC9_ARALL; Uncharacterized protein
STRING	XP_010444159.1	0.0	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6374	27	46

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G62940.1	1e-175	Dof family protein

Publications ? help Back to Top
Miyashima S, et al. Mobile PEAR transcription factors integrate positional cues to prime cambial growth. Nature, 2019. 565(7740): p. 490-494 [PMID:30626969]