PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

TCP

Protein Properties

Length: 419aa MW: 46054.5 Da PI: 8.0692

Description

TCP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa06g046490.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	TCP	125.4	6.1e-39	55	197	2	135
TCP 2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgtssssaseceaesssssasnsssg........ 88 g+kdrhsk+ T++g+RdRRvRls+++a +f+dLqd+LG+d++sk++eWL+++a+ +i el+++ ++a++ ++++++++++n++ + Csa06g046490.1 55 SGGKDRHSKVLTSKGPRDRRVRLSVSTALQFYDLQDRLGYDQPSKAVEWLIKAAEDSISELPSL--NNANFPTDDDENQNHQNQTLTtttvaagg 147 689***********************************************************..44444444555555554444467888899 PP TCP 89 .kaaksaa.kskksqksaasalnlak.esrakarararertrekmriknk 135 ++ +++a +s++++++++s l+l++ e r kar+rarert+++ + +++ Csa06g046490.1 148 tNSLSKSAcSSNSDTSKNSSGLSLSRsELRDKARERARERTAKETKERSS 197 9666666668888888888899999***************99988866 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF03634	1.8E-38	56	194	IPR005333	Transcription factor, TCP
PROSITE profile	PS51369	31.221	57	115	IPR017887	Transcription factor TCP subgroup
PROSITE profile	PS51370	10.205	174	195	IPR017888	CYC/TB1, R domain

Sequence ? help Back to Top
Protein Sequence Length: 419 aa Download sequence Send to blast
MLRKLRDDDE MIGDLMKSNN NNGDVVDNNN NNGNNNRLSR WHHNSSRIIR VSRASGGKDR 60 HSKVLTSKGP RDRRVRLSVS TALQFYDLQD RLGYDQPSKA VEWLIKAAED SISELPSLNN 120 ANFPTDDDEN QNHQNQTLTT TTVAAGGTNS LSKSACSSNS DTSKNSSGLS LSRSELRDKA 180 RERARERTAK ETKERSSDHH HHQSHTTTSF TDLLNSGSDP VNSNRQWMAQ APSASSPMEY 240 FTSGLILGSG QQTHFPISTN SHPFSSISDH HHHHQHHHPH QEFSFVPDHL ISPAGSNGGA 300 FNLDFNMSTP SGAGAAVSAS SGGGFSGFNR GTLQSNSTTS NHQHQHQHQQ QSFLANLQRF 360 PTSSEGGGGG PQFLFGALPA ENHHHNHNHN QNNNNHQFQL YYENGCRNSS DHKGKGKN*

Sequence ? help Back to Top

Protein Sequence Length: 419 aa Download sequence Send to blast

MLRKLRDDDE MIGDLMKSNN NNGDVVDNNN NNGNNNRLSR WHHNSSRIIR VSRASGGKDR  60
HSKVLTSKGP RDRRVRLSVS TALQFYDLQD RLGYDQPSKA VEWLIKAAED SISELPSLNN  120
ANFPTDDDEN QNHQNQTLTT TTVAAGGTNS LSKSACSSNS DTSKNSSGLS LSRSELRDKA  180
RERARERTAK ETKERSSDHH HHQSHTTTSF TDLLNSGSDP VNSNRQWMAQ APSASSPMEY  240
FTSGLILGSG QQTHFPISTN SHPFSSISDH HHHHQHHHPH QEFSFVPDHL ISPAGSNGGA  300
FNLDFNMSTP SGAGAAVSAS SGGGFSGFNR GTLQSNSTTS NHQHQHQHQQ QSFLANLQRF  360
PTSSEGGGGG PQFLFGALPA ENHHHNHNHN QNNNNHQFQL YYENGCRNSS DHKGKGKN*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5zkt_A	3e-23	62	116	1	55	Putative transcription factor PCF6
5zkt_B	3e-23	62	116	1	55	Putative transcription factor PCF6
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Plays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164). Participates in ovule develpment (PubMed:25378179). Participates in ovule develpment (PubMed:25378179). Promotes light-regulated transcription of CHS, CAB, HYH and HY5. Regulates positively photomorphogenesis (e.g. hypocotyl elongation inhibition and cotyledon opening in response to blue light) (PubMed:26596765). {ECO:0000269\|PubMed:12931144, ECO:0000269\|PubMed:17307931, ECO:0000269\|PubMed:25378179, ECO:0000269\|PubMed:26596765}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa06g046490.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by the miRNA miR-JAW (PubMed:12931144). Induced by blue light. Stabilized by light but labile in darkness due to proteasome-dependent proteolysis (at protein level) (PubMed:26596765). {ECO:0000269\|PubMed:12931144, ECO:0000269\|PubMed:26596765}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF367270	1e-142	AF367270.1 Arabidopsis thaliana AT4g18390/F28J12_50 mRNA, complete cds.
GenBank	AF367292	1e-142	AF367292.1 Arabidopsis thaliana AT4g18390/F28J12_50 mRNA, complete cds.
GenBank	AL021710	1e-142	AL021710.1 Arabidopsis thaliana DNA chromosome 4, BAC clone F28J12 (ESSAII project).
GenBank	AL161548	1e-142	AL161548.2 Arabidopsis thaliana DNA chromosome 4, contig fragment No. 48.
GenBank	AY102141	1e-142	AY102141.1 Arabidopsis thaliana AT4g18390/F28J12_50 mRNA, complete cds.
GenBank	CP002687	1e-142	CP002687.1 Arabidopsis thaliana chromosome 4 sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010517540.1	0.0	PREDICTED: transcription factor TCP2-like
Swissprot	Q93V43	0.0	TCP2_ARATH; Transcription factor TCP2
TrEMBL	D7MCT1	0.0	D7MCT1_ARALL; Uncharacterized protein
STRING	XP_010517540.1	0.0	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM7615	25	39

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G18390.2	1e-137	TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 2

Publications ? help Back to Top
Koyama T,Sato F,Ohme-Takagi M Roles of miR319 and TCP Transcription Factors in Leaf Development. Plant Physiol., 2017. 175(2): p. 874-885 [PMID:28842549] Bresso EG,Chorostecki U,Rodriguez RE,Palatnik JF,Schommer C Spatial Control of Gene Expression by miR319-Regulated TCP Transcription Factors in Leaf Development. Plant Physiol., 2018. 176(2): p. 1694-1708 [PMID:29133375]