PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Csa06g038630.1
Organism
Camelina sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina
Family E2F/DP
Protein Properties Length: 486aa    MW: 52871.9 Da    PI: 5.1288
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Csa06g038630.1genomeCSGPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP82.24.5e-26163228171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+llt+kf++l++++++g+++ln++a++L   +v  ++RRiYDi+NVLe+++liek  kn+i wkg
  Csa06g038630.1 163 RYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETL---EV--QKRRIYDITNVLEGIDLIEKPFKNRILWKG 228
                     6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.7E-27161229IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.2E-32163228IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.63E-16163226IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023199.2E-23165228IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440742.88E-32241345No hitNo description
CDDcd146602.48E-48241345No hitNo description
PfamPF164211.1E-32245343IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 486 aa     Download sequence    Send to blast
MSGIVRSSPG SSQPPPPPPH HPPSSSSLGT STPVVPPLRR HLAFASTKPP FHPSDDYHRF  60
TSSSSLTHNT DRSLVNNGFG VVDREEDAVV VRSPSRKRKS TMDMVVAPSN NGFTSSGSNS  120
SPCKTPTKGG RVNIKSKAKG NKSTPQTPIS TNAGSPVPLT PCRYDSSLGL LTKKFVNLIK  180
QAKDGMLDLN KAAETLEVQK RRIYDITNVL EGIDLIEKPF KNRILWKGVD PSSPDDVDAD  240
VSVIQAEIEN LSLEEQALDN QIRQTEERLR DLSENEKNQK WLFVTEEDIK SLPGFQNQTL  300
IAVKAPHGTT LEVPDPDEAV DHPQRRYRII LRSTMGPIDV YLVSEFEGKF EDTNGSVAAP  360
PACLPIASSS GSSGHHDIEA LTVDNTGTAI EHNVSHDHPH PQPGDTSDLN YLQEQVGGML  420
KITPSDVEND ESDYWLLSNA EISMTDIWKT DSKAVIDWEY GIADVGSPPP VMGEITPTAV  480
DSTPR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A9e-26158231276PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
19499SRKRKS
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00293DAPTransfer from AT2G36010Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCsa06g038630.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF2425820.0AF242582.1 Arabidopsis thaliana E2F transcription factor-3 E2F3 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010516811.10.0PREDICTED: transcription factor E2FA
SwissprotQ9FNY00.0E2FA_ARATH; Transcription factor E2FA
TrEMBLD7LIM90.0D7LIM9_ARALL; E2F transcription factor-3
STRINGXP_010516811.10.0(Camelina sativa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.10.0E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]