PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Csa05g018090.1

Organism

Camelina sativa

Taxonomic ID

90675

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

E2F/DP

Protein Properties

Length: 491aa MW: 53286.3 Da PI: 5.0382

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa05g018090.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	82.1	4.5e-26	168	233	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++++g+++ln++a++L +v ++RRiYDi+NVLe+++liek kn+i wkg Csa05g018090.1 168 RYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETL---EV--QKRRIYDITNVLEGIDLIEKPFKNRILWKG 233 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.8E-27	166	235	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	1.63E-16	168	231	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	2.2E-32	168	233	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	9.3E-23	170	233	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	2.56E-48	246	350	No hit	No description
SuperFamily	SSF144074	2.88E-32	246	350	No hit	No description
Pfam	PF16421	1.2E-32	250	348	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 491 aa Download sequence Send to blast
MSGLVRSSPG SSQPPPPPPQ HPPSSSSSLV TSTPVVPPLR RHLAFASTKP PFHPSDDYHR 60 FTSSSSSSLT HNNTDRSLVN NNGFGVVDRD EDAVVVRSPS RKRKSTMDMV VAPSNNGFTS 120 SGSNSSPCKT PTKGGRVNIK SKAKGNKSTP QTPISTNAGS PVPLTPCRYD SSLGLLTKKF 180 VNLIKQAKDG MLDLNKAAET LEVQKRRIYD ITNVLEGIDL IEKPFKNRIL WKGIDASSPD 240 DVDADVSVIQ AEIENLSLEE QALDNQIRQT EERLRDLSEN EKNQKWLFVT EEDIKSLPGF 300 QNQTLIAVKA PHGTTLEVPD PDEAVDHPQR RYRIILRSTM GPIDVYLVSE FEGKFEDTNG 360 SAAAPPACLA IASSSGSSGH HDIEALTVDN TGTAIEHQVS HDHAHPQPGD TSDLNYLQEQ 420 VGGMLKITPS DVENDDSDYW LLSNAEISMT DIWKTDLKAG IDWDYGIADV GTPPPVMGEI 480 TPTAIDSTPR *

Sequence ? help Back to Top

Protein Sequence Length: 491 aa Download sequence Send to blast

MSGLVRSSPG SSQPPPPPPQ HPPSSSSSLV TSTPVVPPLR RHLAFASTKP PFHPSDDYHR  60
FTSSSSSSLT HNNTDRSLVN NNGFGVVDRD EDAVVVRSPS RKRKSTMDMV VAPSNNGFTS  120
SGSNSSPCKT PTKGGRVNIK SKAKGNKSTP QTPISTNAGS PVPLTPCRYD SSLGLLTKKF  180
VNLIKQAKDG MLDLNKAAET LEVQKRRIYD ITNVLEGIDL IEKPFKNRIL WKGIDASSPD  240
DVDADVSVIQ AEIENLSLEE QALDNQIRQT EERLRDLSEN EKNQKWLFVT EEDIKSLPGF  300
QNQTLIAVKA PHGTTLEVPD PDEAVDHPQR RYRIILRSTM GPIDVYLVSE FEGKFEDTNG  360
SAAAPPACLA IASSSGSSGH HDIEALTVDN TGTAIEHQVS HDHAHPQPGD TSDLNYLQEQ  420
VGGMLKITPS DVENDDSDYW LLSNAEISMT DIWKTDLKAG IDWDYGIADV GTPPPVMGEI  480
TPTAIDSTPR *

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	1e-24	163	234	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	99	104	SRKRKS

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa05g018090.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF242582	0.0	AF242582.1 Arabidopsis thaliana E2F transcription factor-3 E2F3 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010509522.1	0.0	PREDICTED: transcription factor E2FA-like
Swissprot	Q9FNY0	0.0	E2FA_ARATH; Transcription factor E2FA
TrEMBL	D7LIM9	0.0	D7LIM9_ARALL; E2F transcription factor-3
TrEMBL	R0HBL7	0.0	R0HBL7_9BRAS; Uncharacterized protein (Fragment)
STRING	XP_010509520.1	0.0	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM808	28	121

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	0.0	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]