PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Csa04g049460.1
Organism
Camelina sativa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina
Family E2F/DP
Protein Properties Length: 478aa    MW: 52288.7 Da    PI: 5.7407
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Csa04g049460.1genomeCSGPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP82.24.3e-26166231171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+llt+kf++l++++++g+++ln++a++L   +v  ++RRiYDi+NVLe+++liek  kn+i wkg
  Csa04g049460.1 166 RYDSSLGLLTKKFVNLIKQAKDGMLDLNKAAETL---EV--QKRRIYDITNVLEGIDLIEKPFKNRILWKG 231
                     6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.7E-27164232IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.63E-16166229IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.2E-32166231IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023199.0E-23168231IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146605.63E-47244348No hitNo description
SuperFamilySSF1440746.02E-32244348No hitNo description
PfamPF164211.5E-32248346IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 478 aa     Download sequence    Send to blast
MSGLVRSSPG SSQPPPPPPH HPPSSSSLVT STPVVPPLRR HLAFASTKPP FHPSDDYHRF  60
TSSSSSSSLT LNTDRSLVNN GFGVVDRDED AVVVRSPSRK RKSTMDMVVA PSNNGFTSSG  120
SNSSPCKTPT KGGRVNIKSK AKGNKSTPQT PISTNAGSPV PLTPCRYDSS LGLLTKKFVN  180
LIKQAKDGML DLNKAAETLE VQKRRIYDIT NVLEGIDLIE KPFKNRILWK GVDPSSPDDV  240
DADVSVIQAE IENLSLEEQA LDNQIRQTEE RLRDLSEKEK NQKWLFVTEE DIKSLPGFQN  300
QTLIAVKAPH GTTLEVPDPD EAVDHPQRRY RIILRSTMGP IDVYLVSEFE GKFEDTNGSV  360
AAPPACLPIA SSSGSSGHHD NEALTVDNTG TAIEHHVSHD HPLPQPGDTS DLNYLQEQVG  420
GMLKITPSDV ENDESDYWLL SNAEISMTDI WKTDCILLQI CKLLLSYSSI IYLHMII*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A6e-26161234276PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
197102SRKRKS
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapCsa04g049460.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF2425820.0AF242582.1 Arabidopsis thaliana E2F transcription factor-3 E2F3 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010505130.10.0PREDICTED: transcription factor E2FA-like
SwissprotQ9FNY00.0E2FA_ARATH; Transcription factor E2FA
TrEMBLD7LIM90.0D7LIM9_ARALL; E2F transcription factor-3
STRINGXP_010505130.10.0(Camelina sativa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.10.0E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]