PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

HSF

Protein Properties

Length: 276aa MW: 31949.1 Da PI: 6.322

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa04g037730.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	106.6	2e-33	28	118	2	101
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellek 96 Fl+k++e+++d+++++++sw++ g+sfvv+d +f++ +Lp++Fkh nf+SF+RQLn+YgF+k++ e+ weF+++ F g+++ll++ Csa04g037730.1 28 FLTKTFEMVDDPNTDQIVSWNRGGTSFVVWDLYSFSTILLPRHFKHCNFSSFIRQLNTYGFRKIEAER---------WEFANEGFLVGQRQLLKN 113 9**************************************************************999.........************** PP XXXXX CS HSF_DNA-bind 97 ikrkk 101 ikr++ Csa04g037730.1 114 IKRRT 118 *97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.5E-35	24	117	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	6.1E-56	24	117	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	6.26E-33	24	117	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	2.6E-29	28	117	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	6.4E-19	28	51	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	6.4E-19	66	78	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	67	91	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	6.4E-19	79	91	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009408	Biological Process	response to heat
GO:0009644	Biological Process	response to high light intensity
GO:0032268	Biological Process	regulation of cellular protein metabolic process
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 276 aa Download sequence Send to blast
MNPFVPEGYD QQPPQPMEGL HEVGPPPFLT KTFEMVDDPN TDQIVSWNRG GTSFVVWDLY 60 SFSTILLPRH FKHCNFSSFI RQLNTYGFRK IEAERWEFAN EGFLVGQRQL LKNIKRRTTF 120 TTSSSSSSTP SSHDAACNEL RREKQVLMME LMSLRQQHQT TKSYVKAMEQ RIEGAEMKQR 180 QMMSFLARAM QSPSFLHQLL KQRDKRIKEI EDETAKRKRG SSSVSELEAL ALEMQGYGKQ 240 RIMLEEDDHH LVVERELDDG FWEELLSDES LASTS*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ldu_A	1e-24	26	119	18	122	Heat shock factor protein 1
5d5u_B	1e-24	19	119	17	131	Heat shock factor protein 1
5d5v_B	1e-24	19	119	17	131	Heat shock factor protein 1
5d5v_D	1e-24	19	119	17	131	Heat shock factor protein 1
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	110	116	LKNIKRR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa04g037730.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010503900.1	0.0	PREDICTED: heat stress transcription factor A-7a-like
Swissprot	Q9SV12	1e-167	HFA7A_ARATH; Heat stress transcription factor A-7a
TrEMBL	D7LTZ9	1e-166	D7LTZ9_ARALL; AT-HSFA7A
STRING	XP_010503900.1	0.0	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1256	28	99

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G51910.1	1e-154	heat shock transcription factor A7A

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Guan Q,Yue X,Zeng H,Zhu J The protein phosphatase RCF2 and its interacting partner NAC019 are critical for heat stress-responsive gene regulation and thermotolerance in Arabidopsis. Plant Cell, 2014. 26(1): p. 438-53 [PMID:24415771] Nie S,Yue H,Xing D A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance. Plant Physiol., 2016. [PMID:26099269]