PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

MYB

Protein Properties

Length: 440aa MW: 49892.6 Da PI: 7.4804

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa04g015890.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	57.6	3e-18	193	239	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g WT+ Ed+llv++v+ +G++ W+ Ia++++ gR +kqc++rw+++l Csa04g015890.1 193 KGQWTPVEDKLLVKLVESHGTKKWSQIAKMLQ-GRVGKQCRERWHNHL 239 799***************************.***********97 PP
2	Myb_DNA-binding	57.1	4.2e-18	246	287	2	45
SSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS Myb_DNA-binding 2 grWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 + WT+eEd +l++a+kq G++ W+ Iar+++ gRt++ +k++w+ Csa04g015890.1 246 DGWTEEEDIILIEAHKQIGNR-WAEIARKLP-GRTENTIKNHWN 287 56*****************.*****.*********8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	28.534	188	243	IPR017930	Myb domain
SuperFamily	SSF46689	1.62E-31	190	286	IPR009057	Homeodomain-like
SMART	SM00717	2.3E-16	192	241	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	2.8E-28	194	247	IPR009057	Homeodomain-like
Pfam	PF13921	1.4E-18	196	254	No hit	No description
CDD	cd00167	1.39E-14	196	239	No hit	No description
SMART	SM00717	2.2E-16	244	292	IPR001005	SANT/Myb domain
PROSITE profile	PS51294	19.671	244	294	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	3.3E-21	248	292	IPR009057	Homeodomain-like
CDD	cd00167	1.46E-12	248	290	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 440 aa Download sequence Send to blast
MEFESVIKMH YPYLAAVIYD DSLTIKDDFS CIHNMHHKPI QINLDMSHLP SMPHTHEIPS 60 KETNRGITPS PCTETFETYF HGTSNDQGFF SMAYTTSQTV ESNVSHVTHE STMWENDQNQ 120 GFIFGTESTF NLALVESNQF IMPKPNLSAN EDTIISRLQN NQVMIKTEQV KKNNKRFQIR 180 RIRKPTKNAS IIKGQWTPVE DKLLVKLVES HGTKKWSQIA KMLQGRVGKQ CRERWHNHLR 240 PDIKKDGWTE EEDIILIEAH KQIGNRWAEI ARKLPGRTEN TIKNHWNATK RRQNSRRAKG 300 KDEVSLQLGS NTLQNYIRSV TYKDDTLTLM TPNSNVGPKN MRDKGKGVMV AVKEDEEDEC 360 KYIVDGVMNM GLDNKTKMPS LAAVSSTCAS TSGSASASGS GVTMELDEPM TDSWMVMHGC 420 DEVMMSEIAL LEMIAHGRL*

Sequence ? help Back to Top

Protein Sequence Length: 440 aa Download sequence Send to blast

MEFESVIKMH YPYLAAVIYD DSLTIKDDFS CIHNMHHKPI QINLDMSHLP SMPHTHEIPS  60
KETNRGITPS PCTETFETYF HGTSNDQGFF SMAYTTSQTV ESNVSHVTHE STMWENDQNQ  120
GFIFGTESTF NLALVESNQF IMPKPNLSAN EDTIISRLQN NQVMIKTEQV KKNNKRFQIR  180
RIRKPTKNAS IIKGQWTPVE DKLLVKLVES HGTKKWSQIA KMLQGRVGKQ CRERWHNHLR  240
PDIKKDGWTE EEDIILIEAH KQIGNRWAEI ARKLPGRTEN TIKNHWNATK RRQNSRRAKG  300
KDEVSLQLGS NTLQNYIRSV TYKDDTLTLM TPNSNVGPKN MRDKGKGVMV AVKEDEEDEC  360
KYIVDGVMNM GLDNKTKMPS LAAVSSTCAS TSGSASASGS GVTMELDEPM TDSWMVMHGC  420
DEVMMSEIAL LEMIAHGRL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1mse_C	7e-45	191	293	2	104	C-Myb DNA-Binding Domain
1msf_C	7e-45	191	293	2	104	C-Myb DNA-Binding Domain
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	169	175	VKKNNKR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that recognizes the motif 5'-TAACGG-3' in the promoter of endosperm-induced genes (PubMed:27681170, PubMed:25194028, PubMed:19066902). Promotes vegetative-to-embryonic transition and the formation of somatic embryos from root explants in a WUS-independent manner but via the expression of embryonic genes (e.g. LEC1, LEC2, FUS3 and WUS) (PubMed:18695688). May play an important role during embryogenesis and seed maturation (PubMed:19066902, PubMed:25194028). Together with MYB115, activates the transcription of S-ACP-DES2/AAD2 and S-ACP-DES3/AAD3 thus promoting the biosynthesis of omega-7 monounsaturated fatty acid in seed endosperm (PubMed:27681170). Regulates negatively maturation genes in the endosperm (PubMed:25194028). {ECO:0000269\|PubMed:18695688, ECO:0000269\|PubMed:19066902, ECO:0000269\|PubMed:25194028, ECO:0000269\|PubMed:27681170}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa04g015890.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by LEC2. {ECO:0000269\|PubMed:25194028}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010502784.1	0.0	PREDICTED: transcription factor MYB46-like
Swissprot	Q9LVW4	0.0	MY118_ARATH; Transcription factor MYB118
TrEMBL	R0FRU3	0.0	R0FRU3_9BRAS; Uncharacterized protein
STRING	XP_010502784.1	0.0	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6052	26	43

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G27785.1	0.0	myb domain protein 118

Publications ? help Back to Top
Troncoso-Ponce MA, et al. Transcriptional Activation of Two Delta-9 Palmitoyl-ACP Desaturase Genes by MYB115 and MYB118 Is Critical for Biosynthesis of Omega-7 Monounsaturated Fatty Acids in the Endosperm of Arabidopsis Seeds. Plant Cell, 2016. 28(10): p. 2666-2682 [PMID:27681170] Ettaki H, et al. Overexpression of MYB115, AAD2, or AAD3 in Arabidopsis thaliana seeds yields contrasting omega-7 contents. PLoS ONE, 2018. 13(1): p. e0192156 [PMID:29381741]