PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

C2H2

Protein Properties

Length: 438aa MW: 46763.4 Da PI: 8.7736

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa03g034380.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	11.8	0.00073	36	59	1	23
EEETTTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirt.H 23 +kC+ C+k s+ s ++ H H Csa03g034380.1 36 FKCHVCHKKLSTASGMVIHVLQvH 59 89*****************87655 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50808	12.716	7	66	IPR003656	Zinc finger, BED-type
SuperFamily	SSF57667	6.64E-5	12	61	No hit	No description
SMART	SM00355	20	12	35	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	14	35	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.084	36	59	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	38	59	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 438 aa Download sequence Send to blast
MGKKKKRATE KVWCYYCDRE FDDEKILVQH QKAKHFKCHV CHKKLSTASG MVIHVLQVHK 60 ENVTKVPNAK TGRDSTDIEI YGMQGIPPDV LAAHYGEEEE EPPAKAAKVE IPSTPLGGAV 120 PRPYGMVYPP QQMPGVVRPM YYPGATIRPP GPVWPMPPPR PQQWYPQNPA VSVPPAAHLG 180 YRPQPLFPVQ NMGMTLPTSA PVVQPSPMTG VTPPGIPSSS PAMPVPQPLF PVVNNSIPSQ 240 ASPFSTPLPV GGAQQPSHAD ALGSVNAYPP NNSIPVQPSP MTGVTPPGIP SSSPAMPVPQ 300 PLFPVVNNSI PSQASPFSTP LPVGGAQQPS HADALGSVNA YPPNNSIPGG TNSHSYASGP 360 NTSGPSIGPP PVIANKAPSN QPNEVYLVWD DEAMSMEERR MSLPKYKVHD ETSQMNSINA 420 AIDRRISESR LAGRMAF*

Sequence ? help Back to Top

Protein Sequence Length: 438 aa Download sequence Send to blast

MGKKKKRATE KVWCYYCDRE FDDEKILVQH QKAKHFKCHV CHKKLSTASG MVIHVLQVHK  60
ENVTKVPNAK TGRDSTDIEI YGMQGIPPDV LAAHYGEEEE EPPAKAAKVE IPSTPLGGAV  120
PRPYGMVYPP QQMPGVVRPM YYPGATIRPP GPVWPMPPPR PQQWYPQNPA VSVPPAAHLG  180
YRPQPLFPVQ NMGMTLPTSA PVVQPSPMTG VTPPGIPSSS PAMPVPQPLF PVVNNSIPSQ  240
ASPFSTPLPV GGAQQPSHAD ALGSVNAYPP NNSIPVQPSP MTGVTPPGIP SSSPAMPVPQ  300
PLFPVVNNSI PSQASPFSTP LPVGGAQQPS HADALGSVNA YPPNNSIPGG TNSHSYASGP  360
NTSGPSIGPP PVIANKAPSN QPNEVYLVWD DEAMSMEERR MSLPKYKVHD ETSQMNSINA  420
AIDRRISESR LAGRMAF*

Functional Description ? help Back to Top
Source	Description
UniProt	Sequence-specific DNA binding factor that recognizes the 5'-CCAAATTTTAAGTTT-3' sequence. Recruits the FRI-C complex to the FLC promoter. Required for FRI-mediated FLC activation, but has no effect on the expression of MAF1, MAF2, MAF3, MAF5, UFC and CO. Dispensable for the reactivation of FLC in early embryogenesis, but required to maintain high levels of FLC expression in later embryonic and vegetative development. {ECO:0000269\|PubMed:17079264, ECO:0000269\|PubMed:17138694, ECO:0000269\|PubMed:19121105, ECO:0000269\|PubMed:21282526}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa03g034380.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by photoperiod or vernalization. {ECO:0000269\|PubMed:17079264, ECO:0000269\|PubMed:17138694}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY085612	0.0	AY085612.1 Arabidopsis thaliana clone 16162 mRNA, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006305544.2	0.0	protein SUPPRESSOR OF FRI 4 isoform X2
Swissprot	Q9C5G0	0.0	SUF4_ARATH; Protein SUPPRESSOR OF FRI 4
TrEMBL	A0A178W1B6	0.0	A0A178W1B6_ARATH; SUF4
STRING	Cagra.1508s0093.1.p	0.0	(Capsella grandiflora)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM7695	17	20

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G30970.1	0.0	C2H2 family protein

Publications ? help Back to Top
Ding L,Kim SY,Michaels SD FLOWERING LOCUS C EXPRESSOR family proteins regulate FLOWERING LOCUS C expression in both winter-annual and rapid-cycling Arabidopsis. Plant Physiol., 2013. 163(1): p. 243-52 [PMID:23899645] Resentini F, et al. SUPPRESSOR OF FRIGIDA (SUF4) Supports Gamete Fusion via Regulating Arabidopsis EC1 Gene Expression. Plant Physiol., 2017. 173(1): p. 155-166 [PMID:27920160]