PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ERF

Protein Properties

Length: 225aa MW: 24569.7 Da PI: 4.5279

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cotton_A_31245_BGI-A2_v1.0	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	59.4	8.5e-19	37	87	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+ykGVr +k +g+Wv+eIr p++ r r++lg+++++e+Aa+a +aa +l+g Cotton_A_31245_BGI-A2_v1.0 37 SKYKGVRKRK-WGKWVSEIRLPNS---RERIWLGSYDSPEKAARAFDAALYCLRG 87 89***999.******933...5***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF00847	2.1E-11	37	87	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.24E-20	37	96	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	5.5E-29	38	96	IPR001471	AP2/ERF domain
SMART	SM00380	9.0E-33	38	101	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	22.431	38	95	IPR001471	AP2/ERF domain
CDD	cd00018	7.55E-29	38	97	No hit	No description
PRINTS	PR00367	5.5E-9	39	50	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.5E-9	61	77	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 225 aa Download sequence Send to blast
MVKPICTTHS SASQTEYASD INTNSCSSNS SSSSSSSKYK GVRKRKWGKW VSEIRLPNSR 60 ERIWLGSYDS PEKAARAFDA ALYCLRGRDA KFNFPENPPE IAGGTSFSPP EIQVVAARFA 120 KGVELETPGN NNSILGTEEY TSSSSGGGAT TQVESRHHEE DMMDWSFLSM LDNNNTNDGG 180 MSDYGFYSNL GHLPGGDDDQ LYPPPIDDDE NGGSAFSPSS FLWNF

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	3e-15	34	95	10	72	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	39	45	KGVRKRK

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KP780185	0.0	KP780185.1 Gossypium hirsutum C-repeat binding factor 2 (CBF2) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017641230.1	1e-167	PREDICTED: ethylene-responsive transcription factor ERF017-like
Swissprot	Q84QC2	3e-51	ERF17_ARATH; Ethylene-responsive transcription factor ERF017
TrEMBL	A0A141AX43	1e-165	A0A141AX43_GOSHI; C-repeat binding factor 2
STRING	EOY30093	8e-72	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1614	28	90

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G19210.1	4e-49	ERF family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Li SJ, et al. The Citrus transcription factor, CitERF13, regulates citric acid accumulation via a protein-protein interaction with the vacuolar proton pump, CitVHA-c4. Sci Rep, 2016. 6: p. 20151 [PMID:26837571] Yin XR, et al. Involvement of an ethylene response factor in chlorophyll degradation during citrus fruit degreening. Plant J., 2016. 86(5): p. 403-12 [PMID:27037684]