PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ERF

Protein Properties

Length: 222aa MW: 25110.2 Da PI: 4.8636

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cotton_A_28628_BGI-A2_v1.0	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	59.5	7.7e-19	89	139	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GVr ++ +g+++AeIrd +++g +r++lg+f++ae Aa a+++a+ +++g Cotton_A_28628_BGI-A2_v1.0 89 SYRGVRKRP-WGKFAAEIRDSTKRG--TRVWLGTFDSAEAAALAYDQAAFSMRG 139 69*****.******66665..***********************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	1.12E-19	88	148	No hit	No description
PROSITE profile	PS51032	22.932	89	147	IPR001471	AP2/ERF domain
Pfam	PF00847	5.3E-14	89	139	IPR001471	AP2/ERF domain
SMART	SM00380	1.0E-36	89	153	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.1E-30	89	148	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	4.32E-22	89	149	IPR016177	DNA-binding domain
PRINTS	PR00367	1.8E-10	90	101	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.8E-10	113	129	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 222 aa Download sequence Send to blast
MEDSWLLQYS KNADSSWFGS EEAFSSTCEW DELLLNFNIS QETAWMDLLG DEEEEEGKKG 60 KVSSECSNNS INGVKEGEVC SEEPKEVKSY RGVRKRPWGK FAAEIRDSTK RGTRVWLGTF 120 DSAEAAALAY DQAAFSMRGP LATLNFPIEA VKASLKELKG RCDEDKGWSP VVELKNRYSL 180 RKRSKNKKIK PKDAALRQQQ NLLVFEDLGA DYLEQLLISS CQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	3e-27	86	149	11	74	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	179	187	LRKRSKNKK
2	181	187	KRSKNKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JX615721	1e-155	JX615721.1 Gossypium hirsutum clone NBRI_GE59864 microsatellite sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017634440.1	1e-162	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	2e-54	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	A0A1U8P8K7	1e-158	A0A1U8P8K7_GOSHI; ethylene-responsive transcription factor 15-like
STRING	Gorai.001G252600.1	1e-136	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM18989	3	8

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G31230.1	5e-38	ethylene-responsive element binding factor 15

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]