PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

M-type_MADS

Protein Properties

Length: 78aa MW: 8513.76 Da PI: 10.1161

Description

M-type_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cotton_A_24831_BGI-A2_v1.0	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	86.8	1.3e-27	10	59	2	51
---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS SRF-TF 2 rienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51 ri+n++ rqvtfskRrng+lKKA+EL +LCdaev v ifsstgkly+++s Cotton_A_24831_BGI-A2_v1.0 10 RIDNSTSRQVTFSKRRNGLLKKAKELAILCDAEVGVTIFSSTGKLYDFAS 59 8***********************************************86 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00432	4.3E-38	1	60	IPR002100	Transcription factor, MADS-box
PROSITE profile	PS50066	31.118	1	61	IPR002100	Transcription factor, MADS-box
CDD	cd00265	1.20E-37	2	61	No hit	No description
SuperFamily	SSF55455	5.76E-28	2	64	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	2.4E-28	3	23	IPR002100	Transcription factor, MADS-box
PROSITE pattern	PS00350	0	3	57	IPR002100	Transcription factor, MADS-box
Pfam	PF00319	1.5E-25	10	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	2.4E-28	23	38	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	2.4E-28	38	59	IPR002100	Transcription factor, MADS-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 78 aa Download sequence Send to blast
MGRGKIVIRR IDNSTSRQVT FSKRRNGLLK KAKELAILCD AEVGVTIFSS TGKLYDFAST 60 SDSEACAIIR GNNELGYA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5f28_A	5e-19	1	60	1	60	MEF2C
5f28_B	5e-19	1	60	1	60	MEF2C
5f28_C	5e-19	1	60	1	60	MEF2C
5f28_D	5e-19	1	60	1	60	MEF2C
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Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. Required for root plasticity in response to nitrate, NO(3)(-). Promotes lateral root growth in a NRT1.1-dependent manner. {ECO:0000269\|PubMed:15667327, ECO:0000269\|PubMed:17148611, ECO:0000269\|PubMed:9430595}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by nitrate in root cell culture, (PubMed:9430595, PubMed:17148611). In roots, seems induced by nitrogen (N) deprivation (e.g. nitrate free medium) but rapidly repressed by N re-supply (e.g. nitrate, glutamine and ammonium) (PubMed:16021502). Slight repression in shoots during nitrogen (N) deprivation. {ECO:0000269\|PubMed:16021502, ECO:0000269\|PubMed:17148611, ECO:0000269\|PubMed:9430595}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KC155659	5e-97	KC155659.1 Gossypium hirsutum MADS box protein MADS64 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001314385.1	1e-35	MADS-box transcription factor 23-like
Refseq	XP_012451269.1	1e-35	PREDICTED: MADS-box transcription factor 23-like isoform X3
Refseq	XP_016730898.1	1e-35	PREDICTED: MADS-box transcription factor 23-like
Refseq	XP_017645601.1	1e-35	PREDICTED: MADS-box transcription factor 23-like isoform X5
Refseq	XP_021283893.1	5e-36	MADS-box transcription factor 27-like
Swissprot	Q9SI38	3e-33	ANR1_ARATH; MADS-box transcription factor ANR1
TrEMBL	A0A061FF38	2e-34	A0A061FF38_THECC; AGAMOUS-like 16
TrEMBL	A0A0D2R1C7	2e-34	A0A0D2R1C7_GOSRA; Uncharacterized protein
TrEMBL	A0A1U8MZB0	3e-34	A0A1U8MZB0_GOSHI; MADS-box transcription factor 23-like
TrEMBL	U5L2C5	3e-34	U5L2C5_GOSHI; MADS box protein MADS64
STRING	Gorai.010G032700.1	3e-35	(Gossypium raimondii)
STRING	EOY15523	4e-35	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM78	28	413

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G14210.1	1e-35	AGAMOUS-like 44

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Yan Y,Wang H,Hamera S,Chen X,Fang R miR444a has multiple functions in the rice nitrate-signaling pathway. Plant J., 2014. 78(1): p. 44-55 [PMID:24460537] Lei L, et al. Nitrogen use efficiency is regulated by interacting proteins relevant to development in wheat. Plant Biotechnol. J., 2018. 16(6): p. 1214-1226 [PMID:29193541] Sun CH, et al. Chrysanthemum MADS-box transcription factor CmANR1 modulates lateral root development via homo-/heterodimerization to influence auxin accumulation in Arabidopsis. Plant Sci., 2018. 266: p. 27-36 [PMID:29241564]