PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

C2H2

Protein Properties

Length: 270aa MW: 28695.8 Da PI: 8.0992

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cotton_A_23497_BGI-A2_v1.0	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12.9	0.00033	103	125	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 y C+ C+ksF++ L H +H Cotton_A_23497_BGI-A2_v1.0 103 YNCSVCNKSFNSYQALGGHKASH 125 89**********99999998887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF13912	4.2E-14	103	127	IPR007087	Zinc finger, C2H2
PROSITE profile	PS50157	9.951	103	125	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.014	103	125	IPR015880	Zinc finger, C2H2-like
SuperFamily	SSF57667	3.33E-9	103	125	No hit	No description
PROSITE pattern	PS00028	0	105	125	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	3.33E-9	155	182	No hit	No description
Pfam	PF13912	1.1E-12	159	184	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.13	160	182	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	9.349	160	182	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	162	182	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 270 aa Download sequence Send to blast
MALEALNSPT TTATPTFHFE DTTNLHCLES FTKRKRSKRP RFDHVTTEEE YLALCLIMLA 60 RGGDANSTDT SVIPQRHRSP TPTASPPPAP APAPTSTEQK VSYNCSVCNK SFNSYQALGG 120 HKASHRKLSG GNDDQSTSTT TSATAGGVIS SALNPSGKTH QCSICHKSFP TGQALGGHKR 180 CHYEGGAGNN ASVTASASGV TTSEGVGSTN TMSHISQRID FDLNLPALPE FSPANFFVSG 240 GDDEVESPHP AKKPRLLVRM PPKMQVNETN

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor involved in abiotic stress responses. Can repress the stress responsive genes DREB1A and LTI78. Probably involved in jasmonate (JA) early signaling response. May regulate the expression of the JA biosynthesis gene LOX3 and control the expression of TIFY10A/JAZ1, a key repressor in the JA signaling cascade. {ECO:0000269\|PubMed:12032082, ECO:0000269\|PubMed:15333755, ECO:0000269\|PubMed:17112521, ECO:0000269\|PubMed:18216250, ECO:0000269\|PubMed:20140232, ECO:0000269\|PubMed:8662738}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salt, cold and drought stresses. Down-regulated by gibberellin. {ECO:0000269\|PubMed:10806347, ECO:0000269\|PubMed:11351099, ECO:0000269\|PubMed:12837949, ECO:0000269\|PubMed:15333755, ECO:0000269\|PubMed:17112521, ECO:0000269\|PubMed:8662738}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017605036.1	0.0	PREDICTED: zinc finger protein ZAT10-like
Swissprot	Q96289	6e-64	ZAT10_ARATH; Zinc finger protein ZAT10
TrEMBL	A0A2P5VZY8	0.0	A0A2P5VZY8_GOSBA; Uncharacterized protein
STRING	Gorai.009G218900.1	1e-168	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1211	28	98

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G27730.1	2e-57	salt tolerance zinc finger

Publications ? help Back to Top
Li C,Chang PP,Ghebremariam KM,Qin L,Liang Y Overexpression of tomato SpMPK3 gene in Arabidopsis enhances the osmotic tolerance. Biochem. Biophys. Res. Commun., 2014. 443(2): p. 357-62 [PMID:24275141] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Shi H,Chan Z The cysteine2/histidine2-type transcription factor ZINC FINGER OF ARABIDOPSIS THALIANA 6-activated C-REPEAT-BINDING FACTOR pathway is essential for melatonin-mediated freezing stress resistance in Arabidopsis. J. Pineal Res., 2014. 57(2): p. 185-91 [PMID:24962049] Munekage YN,Inoue S,Yoneda Y,Yokota A Distinct palisade tissue development processes promoted by leaf autonomous signalling and long-distance signalling in Arabidopsis thaliana. Plant Cell Environ., 2015. 38(6): p. 1116-26 [PMID:25293694] van Buer J,Cvetkovic J,Baier M Cold regulation of plastid ascorbate peroxidases serves as a priming hub controlling ROS signaling in Arabidopsis thaliana. BMC Plant Biol., 2016. 16(1): p. 163 [PMID:27439459] Corrales AR, et al. Multifaceted role of cycling DOF factor 3 (CDF3) in the regulation of flowering time and abiotic stress responses in Arabidopsis. Plant Cell Environ., 2017. 40(5): p. 748-764 [PMID:28044345] Nguyen HM, et al. Ethanol Enhances High-Salinity Stress Tolerance by Detoxifying Reactive Oxygen Species in Arabidopsis thaliana and Rice. Front Plant Sci, 2017. 8: p. 1001 [PMID:28717360] Geilen K,Heilmann M,Hillmer S,Böhmer M WRKY43 regulates polyunsaturated fatty acid content and seed germination under unfavourable growth conditions. Sci Rep, 2017. 7(1): p. 14235 [PMID:29079824] Liu X, et al. Histone Deacetylase AtSRT1 Links Metabolic Flux and Stress Response in Arabidopsis. Mol Plant, 2017. 10(12): p. 1510-1522 [PMID:29107034] Huang K, et al. Arabidopsis calcium-dependent protein kinase AtCPK1 plays a positive role in salt/drought-stress response. Biochem. Biophys. Res. Commun., 2018. 498(1): p. 92-98 [PMID:29196259]