PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

bHLH

Protein Properties

Length: 204aa MW: 22591.1 Da PI: 10.0389

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cotton_A_14902_BGI-A2_v1.0	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.6	1.1e-08	113	153	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L Cotton_A_14902_BGI-A2_v1.0 113 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 153 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.434	104	153	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	4.2E-13	105	162	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	4.19E-14	108	162	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.7E-13	110	159	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.2E-6	114	153	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.50E-6	127	158	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 204 aa Download sequence Send to blast
MEIDHLKSAT TQDQMETMMM QAEYNIYNDV VQLPLASPST FVENPPFITG STPVQPPSTA 60 FCPGLQKKNS MGAMREMIFR IAAMQPIHID PESVKPPKRR NVKISKDPQS VAARHRRERI 120 SERIRILQRL VPGGTKMDTA SMLDEAIHYV KFLKTQVRSL ERAAAVGGGG IGFPLGMSNG 180 GSFFTMGKGF QLHQNDGVQQ FGDV

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017645033.1	1e-151	PREDICTED: transcription factor HEC2-like
Swissprot	Q9SND4	3e-49	HEC2_ARATH; Transcription factor HEC2
TrEMBL	A0A1U8MUV9	1e-149	A0A1U8MUV9_GOSHI; transcription factor HEC2-like
STRING	Gorai.010G020500.1	1e-124	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1559	27	91

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	2e-45	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]