PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

bHLH

Protein Properties

Length: 267aa MW: 29413.4 Da PI: 7.9574

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cotton_A_08659_BGI-A2_v1.0	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26	1.7e-08	176	216	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L Cotton_A_08659_BGI-A2_v1.0 176 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 216 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.434	167	216	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	3.0E-13	168	225	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	2.36E-14	171	228	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.4E-13	173	222	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	8.0E-6	177	216	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.26E-6	190	221	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 267 aa Download sequence Send to blast
MEIDQLKSAT GDEMKTMMMM MQMQMGKLPE FYGDYNNVVE FPHAELADHA TNSSNTSNYS 60 INGNSMPHFV ENPQVGSPGP FANLPTTTIS FNGSTPVQEP SFSFTPDSAS AGELLLLSSG 120 SNASSTSSQK MNSMAAMREM IFRIAAMQPI HIDPESVKPP KRRNVKISKD PQSVAARHRR 180 ERISERIRIL QRLVPGGTKM DTASMLDEAI HYVKFLKTQV QSLERVATSR PAGLGFPVAM 240 SNGSLHPMGK PYQPTQNLQE FGDAWLS

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HQ524787	7e-93	HQ524787.1 Gossypium herbaceum clone NBRI_A_EYI1BW401CDG5H simple sequence repeat marker, mRNA sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017605486.1	0.0	PREDICTED: transcription factor HEC2-like
Swissprot	Q9SND4	8e-48	HEC2_ARATH; Transcription factor HEC2
TrEMBL	A0A2P5WBF3	0.0	A0A2P5WBF3_GOSBA; Uncharacterized protein
STRING	Gorai.009G212900.1	1e-166	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1559	27	91

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	7e-43	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]