PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ERF

Protein Properties

Length: 218aa MW: 24244.9 Da PI: 9.9224

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cotton_A_01957_BGI-A2_v1.0	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	63.1	6.1e-20	45	94	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+W+AeIrdp + + +r++lg+f tae Aa a+++a+++++g Cotton_A_01957_BGI-A2_v1.0 45 HYRGVRQRP-WGKWAAEIRDP---N-KaARVWLGTFATAEAAAIAYDEAALRFKG 94 69*****.******9...3.35*********************9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.730.10	1.1E-32	45	103	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	9.15E-22	45	103	IPR016177	DNA-binding domain
CDD	cd00018	9.86E-20	45	103	No hit	No description
PROSITE profile	PS51032	24.408	45	102	IPR001471	AP2/ERF domain
Pfam	PF00847	7.5E-14	45	94	IPR001471	AP2/ERF domain
SMART	SM00380	8.8E-38	45	108	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.6E-11	46	57	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.6E-11	68	84	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 218 aa Download sequence Send to blast
MIQALTHVIG NDNDNNNPLL VQLHHHNQYQ YQSQHQPQGN VRRIHYRGVR QRPWGKWAAE 60 IRDPNKAARV WLGTFATAEA AAIAYDEAAL RFKGSKAKLN FPERVQRSSG SGYLTISHVV 120 ERVPPPLPPR HSQPTFPNIS DDQLLSGGSN GGEAVSRPAF TSQYPTTLSS SSSSTTLTSK 180 LQQEDLGGFL LKNIGGSSPS SDPPKNKRQC YDYYYSRE

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	4e-26	45	105	2	63	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator of cell proliferation and axillary bud outgrowth. Involved in maintaining the structure of the shoot apical meristem as well as plastochron and phyllotaxy. Activates several genes involved in cell cycle regulation and dormancy breaking, including CYCD3-3, DPA, and BARD1. Strongly down-regulates DRM1, DRMH1, MARD1 and several genes encoding different types of cell wall-remodeling proteins. {ECO:0000269\|PubMed:23616605}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Transiently up-regulated 6 to 15 hours after decapitation. {ECO:0000269\|PubMed:23616605}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017636532.1	1e-162	PREDICTED: ethylene-responsive transcription factor ERF114-like
Refseq	XP_017636533.1	1e-162	PREDICTED: ethylene-responsive transcription factor ERF114-like
Refseq	XP_017636535.1	1e-162	PREDICTED: ethylene-responsive transcription factor ERF114-like
Swissprot	Q9FH54	5e-47	EF114_ARATH; Ethylene-responsive transcription factor ERF114
TrEMBL	A0A2P5Y4S7	1e-129	A0A2P5Y4S7_GOSBA; Uncharacterized protein
STRING	Gorai.007G045100.1	1e-123	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM24314	3	4

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G61890.1	2e-33	ERF family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kong X, et al. PHB3 Maintains Root Stem Cell Niche Identity through ROS-Responsive AP2/ERF Transcription Factors in Arabidopsis. Cell Rep, 2018. 22(5): p. 1350-1363 [PMID:29386120]