PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cla021148
Organism
Citrullus lanatus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Citrullus
Family bHLH
Protein Properties Length: 618aa    MW: 68589.1 Da    PI: 6.1003
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cla021148genomeICuGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.45.1e-13447493455
                HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
        HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI++Lq
  Cla021148 447 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYINELQ 493
                799***********************66......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142155.4E-5552240IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088817.047443492IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.11E-14446497No hitNo description
SuperFamilySSF474595.23E-18446504IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.8E-10447493IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.3E-18447504IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.5E-17449498IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 618 aa     Download sequence    Send to blast
MKIEDGLRSV GGKDEDKTVV AAVLGTRAFN YLMACSVSNE NLFMAVRNDE NLQNKLSDLV  60
ERPNASNFSW NYAIFWQLSH SKSGEWVLGW GDGSCRDPRD GEETDSTQIL SLRLEDESQQ  120
RMKKRALQKL HTLFGGSDED NYALGLDRLT DTEMFFLASM YFSFPRGEGG PGKCLASGKH  180
TWLSDVLNLP SEYCVRSYLA KSAGIRTIVL VPTDVGVVEL GSVRSVNESL ELVQLIRSLF  240
SSQLSLDRVR SSAAMSMMAE RKDESTPFAS LGIAERGEGG GGIPKVFGQT LNSGNMGRSH  300
FREKLAIRKM DERSWEACAN GGRIQFQSPR NGIRSPNLAH VHGLKQGNPA EIYGSPTPPV  360
NNNHEQQLVN GVRDEFCLNP YQSQKLAQMQ IDFSAATSRP SVINRVIADT EHSDVEPQCK  420
EEGPGTDERR PRKRGRKPAN GREEPLNHVE AERQRREKLN QRFYALRAVV PNISKMDKAS  480
LLGDAIAYIN ELQEKVKAME FEREKSGLTS SDATPSEGNP EIENKEQFLD VDIEVEAAHD  540
EVIVKVSCPL ESHPVSRVIK AMKDAQINVV DSKLSEANDK VLHTFVIKSP GSEQLTKEQF  600
IAAFSRDSTS LHPLSTVG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A2e-29441503264Transcription factor MYC2
5gnj_B2e-29441503264Transcription factor MYC2
5gnj_E2e-29441503264Transcription factor MYC2
5gnj_F2e-29441503264Transcription factor MYC2
5gnj_G2e-29441503264Transcription factor MYC2
5gnj_I2e-29441503264Transcription factor MYC2
5gnj_M2e-29441503264Transcription factor MYC2
5gnj_N2e-29441503264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1428436RRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00100PBMTransfer from AT1G01260Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818480.0LN681848.1 Cucumis melo genomic scaffold, anchoredscaffold00006.
GenBankLN7132600.0LN713260.1 Cucumis melo genomic chromosome, chr_6.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008437879.20.0PREDICTED: LOW QUALITY PROTEIN: transcription factor bHLH13
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A1S3AV620.0A0A1S3AV62_CUCME; LOW QUALITY PROTEIN: transcription factor bHLH13
STRINGXP_008437879.10.0(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF54483254
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.30.0bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]