PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Cla016199 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Citrullus
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Family | bHLH | ||||||||
Protein Properties | Length: 702aa MW: 77503.2 Da PI: 5.0613 | ||||||||
Description | bHLH family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | HLH | 39 | 1.4e-12 | 522 | 567 | 4 | 54 |
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +h e+Er+RR+++N++f Lr ++P+ K++Ka+ L A+ YI++L Cla016199 522 NHVEAERQRREKLNQRFYALRAVVPNV-----SKMDKASLLGDAISYINEL 567 799***********************6.....5***************998 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Pfam | PF14215 | 4.6E-55 | 74 | 276 | IPR025610 | Transcription factor MYC/MYB N-terminal |
PROSITE profile | PS50888 | 17.39 | 518 | 567 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
CDD | cd00083 | 9.46E-15 | 521 | 572 | No hit | No description |
SuperFamily | SSF47459 | 2.88E-18 | 521 | 591 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Pfam | PF00010 | 4.6E-10 | 522 | 567 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Gene3D | G3DSA:4.10.280.10 | 2.1E-18 | 522 | 588 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SMART | SM00353 | 5.1E-17 | 524 | 573 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0009269 | Biological Process | response to desiccation | ||||
GO:0009611 | Biological Process | response to wounding | ||||
GO:0009737 | Biological Process | response to abscisic acid | ||||
GO:0009867 | Biological Process | jasmonic acid mediated signaling pathway | ||||
GO:0009963 | Biological Process | positive regulation of flavonoid biosynthetic process | ||||
GO:0010200 | Biological Process | response to chitin | ||||
GO:0043619 | Biological Process | regulation of transcription from RNA polymerase II promoter in response to oxidative stress | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051090 | Biological Process | regulation of sequence-specific DNA binding transcription factor activity | ||||
GO:2000068 | Biological Process | regulation of defense response to insect | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0043565 | Molecular Function | sequence-specific DNA binding | ||||
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 702 aa Download sequence Send to blast |
MTDYRLPPTM NLWADENVSM MDVFTNSDLS SFWVTPPQPQ QLPQPPYFTS TDPSKAVGQA 60 TPPPSMAVFN QETLMQRLQT LIEGAHENWT YAIFWQSSYD YSGRTVLGWG DGYYKGEEDK 120 GKXXXXXXXX XXXXXXXXXX XXXKEKAKSS TSKAEQEHRK KVLRELNSLI SGSPSSEGDA 180 VDEVVTDTEW FYLVSMTQSF ASGVGLPGQA FFDSTPIWVA GSDRLASSVC ERARQGQVFG 240 LQTMVCIPSA NGVVELGSSE LIFQSSDLMN KVRVLFNFNN LEVENWPISG VDQGENDPSS 300 LWISEPSSNA IEITNPVASA SAPAPTPSTT NSQPISKITT ETIENPKSSV VIETPSPVVP 360 PPSQKTHRQS QPIQTQSFFT NRELNFSEFG YENGRLKDGN STSLKPESGE ILNFGESKRS 420 SYPNTDNNLP SGNSLFGGDE NKKKRSPTSR GSNEEGMLSF TSGVILPSSG AVKSGLCAGD 480 SDHSDLEASV IREVESSRVV EPEKRPRKRG RKPANGREEP LNHVEAERQR REKLNQRFYA 540 LRAVVPNVSK MDKASLLGDA ISYINELRGK LQTAESDKED LQKQLDSVKK LIMSSNKDSC 600 ISSSNQPPPD QSSNTNHSDI ETDIDVKIIS WDAMIRIQSS KKNHPAARLM AALEELDLDI 660 NHASISVVND LMIQQATVKM GSRLYTQEQL RIALSSKIGA TR |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4rqw_A | 3e-73 | 69 | 279 | 4 | 195 | Transcription factor MYC3 |
4rqw_B | 3e-73 | 69 | 279 | 4 | 195 | Transcription factor MYC3 |
4rs9_A | 3e-73 | 69 | 279 | 4 | 195 | Transcription factor MYC3 |
4yz6_A | 3e-73 | 69 | 279 | 4 | 195 | Transcription factor MYC3 |
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Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 503 | 511 | KRPRKRGRK |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcriptional activator that binds to the G-box motif (5'-AACGTG-3') found in the promoter of the jasmonate-induced gene LAPA1 (PubMed:15231736). Acts as negative regulator of blue light-mediated photomorphogenesis and positively regulates root growth (PubMed:24483714). Promotes growth in response to the phytohormones abscisic acid (ABA) and jasmonate (JA) (PubMed:24483714). Binds to the G-box motif (5'-CACGTG-3') of the RBCS-3A gene promoter (PubMed:24483714). Acts downstream of the jasmonate (JA) receptor to orchestrate JA-mediated activation of plant responses (PubMed:28733419). Positively regulates both wound-responsive and pathogen-responsive genes through MYC2-targeted transcription factors (MTFs) involved in early response to JA (PubMed:28733419). With JA2L forms a transcription module that regulates wounding-responsive genes (PubMed:28733419). With ERF.C3 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). Plays a critical role in orchestrating JA-mediated defense gene expression during Botrytis cinerea infection (PubMed:28733419). Regulates negatively defense responses to root-knot nematodes, potentially by mediating crosstalk among the hormones strigolactones, abscisic acid (ABA) and jasmonate (JA) (PubMed:30576511). Regulates the termination of JA-mediated defense responses by specifically binding the G-box (5'-CACATG-3') motifs in the promoters of MTB1, MTB2 and MTB3, which are transcription factors that negatively regulates JA signaling (PubMed:30610166). May be involved in JA-induced chilling tolerance, possibly by ameliorating the antioxidant enzyme system of fruit and increasing proline and lycopene levels (PubMed:29528226). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:24483714, ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:29528226, ECO:0000269|PubMed:30576511, ECO:0000269|PubMed:30610166}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00084 | PBM | Transfer from AT1G32640 | Download |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Induced by methyl jasmonate (PubMed:15231736, PubMed:28733419). Induced by wounding (PubMed:15231736). Induced by infection with the fungal pathogen Botrytis cinerea (PubMed:28733419). Induced in fruit by storage in cold (PubMed:29528226). Induced by hydrogen peroxide and infection with root-knot nematodes (PubMed:30576511). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:29528226, ECO:0000269|PubMed:30576511}. |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | LN681824 | 0.0 | LN681824.1 Cucumis melo genomic scaffold, anchoredscaffold01596. | |||
GenBank | LN713258 | 0.0 | LN713258.1 Cucumis melo genomic chromosome, chr_4. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_011652651.1 | 0.0 | PREDICTED: transcription factor MYC2 | ||||
Swissprot | A0A3Q7HRZ6 | 0.0 | MYC2_SOLLC; Transcription factor MYC2 | ||||
TrEMBL | A0A1S3CQ61 | 0.0 | A0A1S3CQ61_CUCME; transcription factor MYC2-like | ||||
STRING | XP_004148475.1 | 0.0 | (Cucumis sativus) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF2938 | 33 | 64 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT1G32640.1 | 0.0 | bHLH family protein |