PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Citrullus

Family

HSF

Protein Properties

Length: 296aa MW: 33273.3 Da PI: 6.5266

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cla000713	genome	ICuGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	117.2	9.9e-37	10	101	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 Fl+k+y++++d+++++++sw+++g++f+v+++ +fa+++Lp+yFkh+nf+SFvRQLn+YgF+k+ ++ weF++++F++g+kell+ki+ Cla000713 10 FLTKTYQLVDDPSTDDVVSWNQSGSTFIVWKTADFARDLLPNYFKHNNFSSFVRQLNTYGFRKIVPDK---------WEFANDNFQRGHKELLSKIR 97 9**************************************************************999.........****************** PP XXXX CS HSF_DNA-bind 99 rkks 102 r+k Cla000713 98 RRKA 101 *985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00415	1.6E-59	6	99	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	1.5E-33	7	99	IPR011991	Winged helix-turn-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	7.3E-38	7	99	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	4.6E-32	10	99	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.3E-21	10	33	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.3E-21	48	60	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	49	73	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.3E-21	61	73	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009408	Biological Process	response to heat
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 296 aa Download sequence Send to blast
MAHRSLPAPF LTKTYQLVDD PSTDDVVSWN QSGSTFIVWK TADFARDLLP NYFKHNNFSS 60 FVRQLNTYGF RKIVPDKWEF ANDNFQRGHK ELLSKIRRRK AVMISQPLQT VHPAKSGGGG 120 NSSPANSGED IGSTSTSSPD SKNPGSVEMG TVAQFADLTE ENEKLKKDNE MLNSELVQTK 180 KQCDELVAFL TDYLKVAPDQ ISRIMRQEGN NRDSSQCNDG ADLKSEGKVN EEEEEEEEEE 240 DGETLKLFGV WLKGKKEKKM KRGRDEKMGC SKAPHAKAMK SVEMHAPLMR SSNLCN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	2e-25	5	99	25	129	Heat shock factor protein 1
5d5v_B	2e-25	5	99	25	129	Heat shock factor protein 1
5d5v_D	2e-25	5	99	25	129	Heat shock factor protein 1
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Functional Description ? help Back to Top
Source	Description
UniProt	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681875	1e-170	LN681875.1 Cucumis melo genomic scaffold, anchoredscaffold00007.
GenBank	LN713262	1e-170	LN713262.1 Cucumis melo genomic chromosome, chr_8.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_022950044.1	1e-170	heat shock factor protein HSF24-like
Refseq	XP_022950046.1	1e-170	heat shock factor protein HSF24-like
Swissprot	P22335	1e-110	HSF24_SOLPE; Heat shock factor protein HSF24
TrEMBL	A0A1S3B0S0	1e-162	A0A1S3B0S0_CUCME; LOW QUALITY PROTEIN: heat shock factor protein HSF24
STRING	XP_004141916.1	1e-156	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF7114	32	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36990.1	2e-82	heat shock factor 4

Publications ? help Back to Top
Scharf KD, et al. Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA-binding domain of the yeast HSF. EMBO J., 1990. 9(13): p. 4495-501 [PMID:2148291]