PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus

Family

bHLH

Protein Properties

Length: 559aa MW: 59481.9 Da PI: 6.2512

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Ciclev10031122m	genome	ICGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	27.2	7e-09	374	422	3	55
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR++i +++ L++l+P + sk Ka +L + ++Y++sLq Ciclev10031122m 374 NSHSLAERVRREKISERMKFLQDLVPGC----SKVTGKAVMLDEIINYVQSLQ 422 58***********************9....556***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00083	3.25E-11	369	426	No hit	No description
SuperFamily	SSF47459	7.33E-17	369	440	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.485	371	421	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.4E-16	372	439	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.1E-6	374	422	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	7.7E-10	377	427	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 559 aa Download sequence Send to blast
MDMSDKDKFV LEKRNDNPMD YHSPNMSSDW QFSGANLANA ALNLVPTGNP LGVGSSSCSS 60 APMVDSFNQT IWDHPTNSQS LGYCNIDAQH NASSSNALGI RKGSSASLRS CIDRPLDIGW 120 NPASSMIKGG IFLPNAPGMF PQSLSQFPAD SAFIERAARF SSFSGGNFCD MMNTFGTPEP 180 TGLYSRGRGM MQGPQEVFAG NGLKSLSGGQ SQKNEMNVAE VSKDASLSVE HGASDGSTLK 240 NERKGESLVN SHGEAKQGVG GSGGDSDEAE FSGGGGQDEP SAVEGTGGEP SAKGLSSKKR 300 KRNGQDIEFD QAKGGQSSGE AAKDNTENQR KGDHKPSSTG NKSAGKQGKQ GSQTSDPPKE 360 EYIHVRARRG QATNSHSLAE RVRREKISER MKFLQDLVPG CSKVTGKAVM LDEIINYVQS 420 LQRQVEFLSM KLATVNPRLD FNIEELLAKD VLQSRAGPSS TLGFSPDMPL VYPPVHQSQA 480 GLMHGALPGM GNPSDILRRT INSQLTPMTG GFKEPSQVAN VWEDELHNVV QMSYGTSAPS 540 DSQDVNGSTP PGHMKVEL*

Sequence ? help Back to Top

Protein Sequence Length: 559 aa Download sequence Send to blast

MDMSDKDKFV LEKRNDNPMD YHSPNMSSDW QFSGANLANA ALNLVPTGNP LGVGSSSCSS  60
APMVDSFNQT IWDHPTNSQS LGYCNIDAQH NASSSNALGI RKGSSASLRS CIDRPLDIGW  120
NPASSMIKGG IFLPNAPGMF PQSLSQFPAD SAFIERAARF SSFSGGNFCD MMNTFGTPEP  180
TGLYSRGRGM MQGPQEVFAG NGLKSLSGGQ SQKNEMNVAE VSKDASLSVE HGASDGSTLK  240
NERKGESLVN SHGEAKQGVG GSGGDSDEAE FSGGGGQDEP SAVEGTGGEP SAKGLSSKKR  300
KRNGQDIEFD QAKGGQSSGE AAKDNTENQR KGDHKPSSTG NKSAGKQGKQ GSQTSDPPKE  360
EYIHVRARRG QATNSHSLAE RVRREKISER MKFLQDLVPG CSKVTGKAVM LDEIINYVQS  420
LQRQVEFLSM KLATVNPRLD FNIEELLAKD VLQSRAGPSS TLGFSPDMPL VYPPVHQSQA  480
GLMHGALPGM GNPSDILRRT INSQLTPMTG GFKEPSQVAN VWEDELHNVV QMSYGTSAPS  540
DSQDVNGSTP PGHMKVEL*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed constitutively in roots, stems, and flowers. {ECO:0000269\|PubMed:12679534}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in cell elongation. Regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif. {ECO:0000269\|PubMed:23161888}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006437828.1	0.0	transcription factor bHLH49 isoform X1
Refseq	XP_024041500.1	0.0	transcription factor bHLH49 isoform X1
Swissprot	Q9CAA9	1e-148	BH049_ARATH; Transcription factor bHLH49
TrEMBL	V4ST89	0.0	V4ST89_9ROSI; Uncharacterized protein
STRING	XP_006437828.1	0.0	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5900	25	44

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G68920.3	1e-152	bHLH family protein

Link Out ? help Back to Top
Phytozome	Ciclev10031122m
Entrez Gene	18045026

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Tian C, et al. An organ boundary-enriched gene regulatory network uncovers regulatory hierarchies underlying axillary meristem initiation. Mol. Syst. Biol., 2014. 10: p. 755 [PMID:25358340] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]