PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus

Family

G2-like

Protein Properties

Length: 379aa MW: 41634.8 Da PI: 6.4142

Description

G2-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Ciclev10028658m	genome	ICGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	94.9	6.4e-30	156	209	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 +prl+Wtp+LH+rFv++v++L G+++A+Pkti++lm+v+gLt+e+v+SHLQkYRl Ciclev10028658m 156 RPRLVWTPQLHKRFVDVVAHL-GIKNAVPKTIMQLMNVEGLTRENVASHLQKYRL 209 59*****************.******************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	10.061	153	212	IPR017930	Myb domain
SuperFamily	SSF46689	1.97E-19	153	213	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	4.4E-30	155	214	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	2.0E-23	157	209	IPR006447	Myb domain, plants
Pfam	PF00249	7.1E-8	159	208	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0042753	Biological Process	positive regulation of circadian rhythm
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 379 aa Download sequence Send to blast
MGEEVRMTEY EVNDKGDYNG DDERIPEWEM GLPNGTDLTP LSQSLIPPEL ASAFSILPVP 60 CRTHLDVNRA SQTTLSSIRG SRAHSLSSTD NNNSNNLKTL TENRDPMVTE TEEQDQNGSF 120 ADSRSKSRRP DCTEEADSAL RTDNSNEDPS ARTLKRPRLV WTPQLHKRFV DVVAHLGIKN 180 AVPKTIMQLM NVEGLTRENV ASHLQKYRLY LKRMQGLSND DPSSSDHQLF ASTPVPPQCL 240 PYESTNGGPH VGHLCNSNNN NNNGSINNNN NNNDGNSNNG SGNSGHVGMA AYGAPAGMMT 300 APMYGMINHQ GFHHGHGFDP SMYNMNMNMG MGMNMNMGMN NMMHQQRDWS VNKHGYGHGH 360 GQGSVVSYPQ HVAPSSDK*

Sequence ? help Back to Top

Protein Sequence Length: 379 aa Download sequence Send to blast

MGEEVRMTEY EVNDKGDYNG DDERIPEWEM GLPNGTDLTP LSQSLIPPEL ASAFSILPVP  60
CRTHLDVNRA SQTTLSSIRG SRAHSLSSTD NNNSNNLKTL TENRDPMVTE TEEQDQNGSF  120
ADSRSKSRRP DCTEEADSAL RTDNSNEDPS ARTLKRPRLV WTPQLHKRFV DVVAHLGIKN  180
AVPKTIMQLM NVEGLTRENV ASHLQKYRLY LKRMQGLSND DPSSSDHQLF ASTPVPPQCL  240
PYESTNGGPH VGHLCNSNNN NNNGSINNNN NNNDGNSNNG SGNSGHVGMA AYGAPAGMMT  300
APMYGMINHQ GFHHGHGFDP SMYNMNMNMG MGMNMNMGMN NMMHQQRDWS VNKHGYGHGH  360
GQGSVVSYPQ HVAPSSDK*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5lxu_A	2e-34	156	212	1	57	Transcription factor LUX
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that is essential for the generation of the circadian clock oscillation. Is necessary for activation of CCA1 and LHY expression. Is coregulated with TOC1 and seems to be repressed by CCA1 and LHY by direct binding of these proteins to the evening element in the LUX promoter. Directly regulates the expression of PRR9, a major component of the morning transcriptional feedback circuit, by binding specific sites on PRR9 promoter. Binds to its own promoter, inducing a negative auto-regulatory feedback loop within the core clock. Binds to ELF3 and associates with ELF4 in a diurnal complex which is required for the expression of the growth-promoting transcription factors PIF4 and PIF5 and subsequent hypocotyl growth in the early evening. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:21236673, ECO:0000269\|PubMed:21753751, ECO:0000269\|PubMed:22311777}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00014	PBM	Transfer from AT3G46640	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian oscillation with peaks at subjective dusk. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:17132630, ECO:0000269\|PubMed:21753751}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006424880.1	0.0	transcription factor LUX
Refseq	XP_006488371.1	0.0	transcription factor LUX
Swissprot	Q9SNB4	3e-84	PCL1_ARATH; Transcription factor LUX
TrEMBL	V4SH30	0.0	V4SH30_9ROSI; Uncharacterized protein
STRING	XP_006488371.1	0.0	(Citrus sinensis)
STRING	XP_006424879.1	0.0	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4055	27	58

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G46640.2	1e-82	G2-like family protein

Link Out ? help Back to Top
Phytozome	Ciclev10028658m
Entrez Gene	18035661

Publications ? help Back to Top
Higham CF,Husmeier D A Bayesian approach for parameter estimation in the extended clock gene circuit of Arabidopsis thaliana. BMC Bioinformatics, 2013. 14 Suppl 10: p. S3 [PMID:24267177]