PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus

Family

MYB

Protein Properties

Length: 432aa MW: 49404.2 Da PI: 6.7937

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Ciclev10024427m	genome	ICGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	58.9	1.1e-18	186	232	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g WTteEd ll+++v q+G + W+ Ia++++ gR +kqc++rw+++l Ciclev10024427m 186 KGQWTTEEDRLLIRLVDQFGIRKWSHIAQMLP-GRIGKQCRERWHNHL 232 799***************************.***********97 PP
2	Myb_DNA-binding	55.9	9.6e-18	240	280	3	45
SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS Myb_DNA-binding 3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 W++eEd+ l++a+++ G++ W+ Ia++++ gRt++++k++w+ Ciclev10024427m 240 IWSEEEDKALIEAHAEIGNK-WAEIAKRLP-GRTENSIKNHWN 280 6*****************.*****.*********8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	29.292	181	236	IPR017930	Myb domain
SuperFamily	SSF46689	2.34E-31	183	279	IPR009057	Homeodomain-like
SMART	SM00717	2.2E-16	185	234	IPR001005	SANT/Myb domain
Pfam	PF00249	5.9E-17	186	232	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	2.4E-25	187	236	IPR009057	Homeodomain-like
CDD	cd00167	2.06E-15	189	232	No hit	No description
SMART	SM00717	7.6E-17	237	285	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	3.6E-22	237	285	IPR009057	Homeodomain-like
PROSITE profile	PS51294	20.191	237	287	IPR017930	Myb domain
CDD	cd00167	1.38E-13	241	283	No hit	No description
Pfam	PF00249	1.8E-16	241	280	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010183	Biological Process	pollen tube guidance
GO:0045697	Biological Process	regulation of synergid differentiation
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 432 aa Download sequence Send to blast
MKPELPFEVP SSKGTHITNN LQDFDRHHHD LDDDDGRHHL FVNLNGSSST NPFAVHTPCF 60 ESLDAFPYNY SSSLNFDFYE CKPFADHNYS SGNGQVMDNF QSGGYLNHHQ QQQVNPVDIL 120 GSDHRSHMQL DFQEMKPVNF LVSDEVSCVS AGNGYYKKAG MDKNNNRAYH SVRKTMKIGK 180 KSNVVKGQWT TEEDRLLIRL VDQFGIRKWS HIAQMLPGRI GKQCRERWHN HLRPDIKKDI 240 WSEEEDKALI EAHAEIGNKW AEIAKRLPGR TENSIKNHWN ATKRRQFSKR KCRSKYPRAS 300 LLQDYIKSLN LDAAGSSKHQ RKNSSNINAN NKSKAATKSS PPAAAEQDFC RSDHLVPDFD 360 FNEVPDFDFD DKLFDENCSI DSLIEEMTCA PVVDHQKSLD MKVPPLDVPP VMEFEVKKEL 420 DLVEMISEAN L*

Sequence ? help Back to Top

Protein Sequence Length: 432 aa Download sequence Send to blast

MKPELPFEVP SSKGTHITNN LQDFDRHHHD LDDDDGRHHL FVNLNGSSST NPFAVHTPCF  60
ESLDAFPYNY SSSLNFDFYE CKPFADHNYS SGNGQVMDNF QSGGYLNHHQ QQQVNPVDIL  120
GSDHRSHMQL DFQEMKPVNF LVSDEVSCVS AGNGYYKKAG MDKNNNRAYH SVRKTMKIGK  180
KSNVVKGQWT TEEDRLLIRL VDQFGIRKWS HIAQMLPGRI GKQCRERWHN HLRPDIKKDI  240
WSEEEDKALI EAHAEIGNKW AEIAKRLPGR TENSIKNHWN ATKRRQFSKR KCRSKYPRAS  300
LLQDYIKSLN LDAAGSSKHQ RKNSSNINAN NKSKAATKSS PPAAAEQDFC RSDHLVPDFD  360
FNEVPDFDFD DKLFDENCSI DSLIEEMTCA PVVDHQKSLD MKVPPLDVPP VMEFEVKKEL  420
DLVEMISEAN L*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1mse_C	1e-43	184	286	2	104	C-Myb DNA-Binding Domain
1msf_C	1e-43	184	286	2	104	C-Myb DNA-Binding Domain
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed in cellularized but not uncellularized female gametophytes. {ECO:0000269\|PubMed:16214903}.
Uniprot	TISSUE SPECIFICITY: Expressed at high levels in the synergid cells of the female gametophyte, and at lower levels in the endosperm of young seeds and the trichomes of young leaves and sepals. {ECO:0000269\|PubMed:16214903, ECO:0000269\|PubMed:17693534}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds to the motif 5'-GTAACNT-3' in the promoter of target genes (e.g. DD11 and DD18) and promotes their expression within synergid cells (e.g. in the filiform apparatus) in ovules (PubMed:16214903, PubMed:17693534, PubMed:18410484, PubMed:17937500). Required for the formation of the filiform apparatus during synergid cell differentiation in the female gametophyte (PubMed:16214903). Involved in pollen tube guidance to the micropyle (PubMed:16214903, PubMed:17937500, PubMed:23093426). {ECO:0000269\|PubMed:16214903, ECO:0000269\|PubMed:17693534, ECO:0000269\|PubMed:17937500, ECO:0000269\|PubMed:18410484, ECO:0000269\|PubMed:23093426}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00442	DAP	Transfer from AT4G18770	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006439837.2	0.0	transcription factor MYB98
Swissprot	Q9S7L2	1e-100	MYB98_ARATH; Transcription factor MYB98
TrEMBL	V4TI85	0.0	V4TI85_9ROSI; Uncharacterized protein
STRING	XP_006439837.1	0.0	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5869	28	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G18770.1	5e-99	myb domain protein 98

Link Out ? help Back to Top
Phytozome	Ciclev10024427m
Entrez Gene	18050309

Publications ? help Back to Top
Mendes MA, et al. Live and let die: a REM complex promotes fertilization through synergid cell death in Arabidopsis. Development, 2016. 143(15): p. 2780-90 [PMID:27338615]