PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ciclev10021611m
Common NameCICLE_v10021611mg
Organism
Citrus clementina
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus
Family ERF
Protein Properties Length: 276aa    MW: 30386.6 Da    PI: 4.7154
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ciclev10021611mgenomeICGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP261.81.6e-193585155
              AP2  1 sgykGVrwdkkrgrWvAeIrd.psengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                     s++ GVr+++ +grWvAeI+d      k+ r++lg+f taeeAa+a+++a+  l+g
  Ciclev10021611m 35 SKFVGVRQRP-SGRWVAEIKDtT----KKIRVWLGTFETAEEAARAYDEAACLLRG 85
                     79********.7*********33....36**********************99987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541713.07E-203595IPR016177DNA-binding domain
PfamPF008472.9E-143585IPR001471AP2/ERF domain
CDDcd000182.34E-323593No hitNo description
Gene3DG3DSA:3.30.730.101.0E-283693IPR001471AP2/ERF domain
SMARTSM003806.7E-373699IPR001471AP2/ERF domain
PROSITE profilePS5103220.1263693IPR001471AP2/ERF domain
PRINTSPR003674.1E-83748IPR001471AP2/ERF domain
PRINTSPR003674.1E-85975IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 276 aa     Download sequence    Send to blast
MEIQFQQQKQ LQKACINQVN RAGKFKGRNR TKSNSKFVGV RQRPSGRWVA EIKDTTKKIR  60
VWLGTFETAE EAARAYDEAA CLLRGSNTRT NFDTNVSFDS PLASRIRNLV NNKKGCQQQS  120
VEASATTTTT AYTPTSTATS NSSCTSCSGV ISGELSSSSS DIIQDAQLFD DAYKPDLSKC  180
IEDFELGSAQ IDHSWGSGNG VDQFSYTQEL LDLPENGALP ETTTDSEFAE FERMKVERQI  240
SASLYAINGV QEYMDTVHDA AEAFWDLPPL CSYAL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A9e-1627102581Ethylene-responsive transcription factor ERF096
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, root hairs and leaves (PubMed:17827349). Expressed in root epidermis and root hairs (PubMed:23077241). {ECO:0000269|PubMed:17827349, ECO:0000269|PubMed:23077241}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in symbiotic nodule signaling in response to rhizobial Nod factors (NFs) (PubMed:17449807, PubMed:17827349). Binds to the GCC-box (NF-responsive box) of ENOD11 promoter. Acts as transcriptional activator of NF-responsive box-containing target gene promoters in root hairs (PubMed:17827349). Functions as a transcriptional regulator required for root infection by symbiotic rhizobia, infection thread (IT) formation and maintenance, and nodule development. Necessary for NF-induced gene expression and spontaneous nodulation activated by CCAMK. Functions downstream of CCAMK to activate nodulation gene expression (PubMed:17449807). Involved in early stages of root nodule development. Functions redundantly with ERN2. Is essential with ERN2 for the initiation of root hair infection, and nodule organogenesis and development. Required for accurate expression of the NF signaling genes ENOD11 and ENOD12 (PubMed:23077241, PubMed:27208242). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349, ECO:0000269|PubMed:23077241, ECO:0000269|PubMed:27208242}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced in roots from 1 to 21 day after inoculation with Sinorhizobium meliloti (PubMed:17449807). Induced by Nod factors in root hairs (PubMed:17827349). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006443442.10.0ethylene-responsive transcription factor RAP2-11
RefseqXP_006479125.10.0ethylene-responsive transcription factor RAP2-11
SwissprotA2Q5W11e-105ERN1_MEDTR; Ethylene-responsive transcription factor ERN1
TrEMBLA0A067EIU60.0A0A067EIU6_CITSI; Uncharacterized protein
TrEMBLV4TTC40.0V4TTC4_9ROSI; Uncharacterized protein
STRINGXP_006479125.10.0(Citrus sinensis)
STRINGXP_006443442.10.0(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM16007712
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G19790.17e-27related to AP2 11
Publications ? help Back to Top
  1. Cerri MR, et al.
    Medicago truncatula ERN transcription factors: regulatory interplay with NSP1/NSP2 GRAS factors and expression dynamics throughout rhizobial infection.
    Plant Physiol., 2012. 160(4): p. 2155-72
    [PMID:23077241]
  2. Tang H, et al.
    An improved genome release (version Mt4.0) for the model legume Medicago truncatula.
    BMC Genomics, 2014. 15: p. 312
    [PMID:24767513]
  3. Cerri MR, et al.
    The Symbiosis-Related ERN Transcription Factors Act in Concert to Coordinate Rhizobial Host Root Infection.
    Plant Physiol., 2016. 171(2): p. 1037-54
    [PMID:27208242]