PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus

Family

WRKY

Protein Properties

Length: 603aa MW: 65117 Da PI: 6.94

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Ciclev10019383m	genome	ICGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.9	2.8e-30	246	305	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a +Cpv+k+v+r+aed +v+++tYeg+Hnh+ Ciclev10019383m 246 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApSCPVRKQVQRCAEDMSVLITTYEGTHNHP 305 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.2E-31	231	307	IPR003657	WRKY domain
SuperFamily	SSF118290	3.01E-27	239	307	IPR003657	WRKY domain
PROSITE profile	PS50811	28.483	241	307	IPR003657	WRKY domain
SMART	SM00774	1.6E-36	246	306	IPR003657	WRKY domain
Pfam	PF03106	8.5E-27	247	305	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 603 aa Download sequence Send to blast
MEEKRAMDDV LRISGRTGAA ADEEKGVDSV GDDHKEEVVA EHPILTNAKG SSLGPESKPS 60 SSSRKEQDDQ LETARAEMGE VRQENEKLKM YLNRIMKDYQ TLQTQFVNIV HQEAKKSTET 120 SNDHDRDKEE VELVSLSLGR FPSDSKKDEK NKTSSLVKEE KQFQEGLSLA LDCKFEASNK 180 SDANESLTNR SPAQSLEEPK EEAGETWPPG KGLNKTMRNG DDEMLQQSHV KKARVSVRAR 240 CDTPTMNDGC QWRKYGQKIA KGNPCPRAYY RCTVAPSCPV RKQVQRCAED MSVLITTYEG 300 THNHPLPVSA TAMASTTSAA ASMLLSGSTS SSSSSSRPGS TAAITAPNNL LMHGLNFYLS 360 DKSKQIYAPN SSSSLSASPL HPTITLDLTT TTAPSSSSSP FSRFTSNYPP APRYSSTNLN 420 FSSTESSSLM SWSNNGLLSY GSCTQPYIKN NQIGSLNMGS RQPADNIFQS YMQKNNPNPN 480 LPPQQSLPAE TIAAATKAIT ADPSFQSALA VALKSIIGNG NGSGVNNNQV NGDNLGQKLK 540 WGEQFLETVK GGGCATSYLN KSSSASSHHQ PGSLIFLPPN SLPFSTSKSA SASPADDREH 600 TD*

Sequence ? help Back to Top

Protein Sequence Length: 603 aa Download sequence Send to blast

MEEKRAMDDV LRISGRTGAA ADEEKGVDSV GDDHKEEVVA EHPILTNAKG SSLGPESKPS  60
SSSRKEQDDQ LETARAEMGE VRQENEKLKM YLNRIMKDYQ TLQTQFVNIV HQEAKKSTET  120
SNDHDRDKEE VELVSLSLGR FPSDSKKDEK NKTSSLVKEE KQFQEGLSLA LDCKFEASNK  180
SDANESLTNR SPAQSLEEPK EEAGETWPPG KGLNKTMRNG DDEMLQQSHV KKARVSVRAR  240
CDTPTMNDGC QWRKYGQKIA KGNPCPRAYY RCTVAPSCPV RKQVQRCAED MSVLITTYEG  300
THNHPLPVSA TAMASTTSAA ASMLLSGSTS SSSSSSRPGS TAAITAPNNL LMHGLNFYLS  360
DKSKQIYAPN SSSSLSASPL HPTITLDLTT TTAPSSSSSP FSRFTSNYPP APRYSSTNLN  420
FSSTESSSLM SWSNNGLLSY GSCTQPYIKN NQIGSLNMGS RQPADNIFQS YMQKNNPNPN  480
LPPQQSLPAE TIAAATKAIT ADPSFQSALA VALKSIIGNG NGSGVNNNQV NGDNLGQKLK  540
WGEQFLETVK GGGCATSYLN KSSSASSHHQ PGSLIFLPPN SLPFSTSKSA SASPADDREH  600
TD*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	1e-21	246	307	17	77	Probable WRKY transcription factor 4
2lex_A	1e-21	246	307	17	77	Probable WRKY transcription factor 4
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, trichomes and fruits. {ECO:0000269\|PubMed:24884371}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006439640.1	0.0	probable WRKY transcription factor 61
Swissprot	A0A3Q7GFB5	1e-131	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	V4TMH9	0.0	V4TMH9_9ROSI; Uncharacterized protein
STRING	XP_006439640.1	0.0	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2959	28	68

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	2e-71	WRKY DNA-binding protein 72

Link Out ? help Back to Top
Phytozome	Ciclev10019383m
Entrez Gene	18046597

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]