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Plant Transcription
Factor Database
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Transcription Factor Information
Basic
Information? help
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TF ID |
Ciclev10011632m |
Common Name | CICLE_v10011632mg |
Organism |
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Taxonomic ID |
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Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus
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Family |
E2F/DP |
Protein Properties |
Length: 479aa MW: 53269.6 Da PI: 4.9626 |
Description |
E2F/DP family protein |
Gene Model |
Gene Model ID |
Type |
Source |
Coding Sequence |
Ciclev10011632m | genome | ICGC | View CDS |
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Signature Domain? help Back to Top |
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No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
1 | E2F_TDP | 86.1 | 2.6e-27 | 154 | 219 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg
Ciclev10011632m 154 RYDSSLGLLTKKFINLIKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 219
6899******************************...99..****************************98 PP
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Gene Ontology ? help Back to Top |
GO Term |
GO Category |
GO Description |
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated |
GO:0051446 | Biological Process | positive regulation of meiotic cell cycle |
GO:0005634 | Cellular Component | nucleus |
GO:0005667 | Cellular Component | transcription factor complex |
GO:0003677 | Molecular Function | DNA binding |
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
Protein Sequence Length: 479 aa
Download sequence Send
to blast |
MSGASRAPYR TAPPPPNPPR SGPIVPPIKR HLAFVTTKPP FVPSDDYHRF SNTRRAADQE 60 PEAIVVRSPQ LKRKNGMEDN EVETSEWVGS PGLTNISNGP FHTPVSAKGG RVNNRSKGIK 120 GNRSTPQTPV SNAGEKISYH LGSPSALTPA GSCRYDSSLG LLTKKFINLI KHAEDGILDL 180 NKAAETLEVQ KRRIYDITNV LEGIGLIEKK LKNRIRWKGL DNSIPGEVDA DASILQADID 240 NLSMEELRVD EQTRELRERL RELIENENNR KWLFVTEEDI KNLHCFQNQT LIAIKAPQGT 300 TLEVPDPDEA VDYPQRRYRI ILRSTMGPID VYLVSRFEEK FEETNSVEPP ASVPPVSSSD 360 SNENQVKEII NVDRAGNETE AQAQQAHQIY SDLNSSQEVV GGMMKIVPSD VDNDADYWLL 420 SDADVSITDM WKTDCAEWDG VNMLHAEFGM SDACTPTPQT PPSRITEVPS TDFNPIHR*
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Expression --
Description ? help
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Source |
Description |
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}. |
Uniprot | TISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}. |
Functional Description ? help
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Source |
Description |
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |