PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus

Family

C2H2

Protein Properties

Length: 376aa MW: 42331.8 Da PI: 6.6096

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Ciclev10005189m	genome	ICGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14.4	0.00011	298	320	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C +Cgk F + + ++H +++ Ciclev10005189m 298 FMCRKCGKAFAVRGDWRTHEKNC 320 89*****************9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00355	0.58	214	236	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	9.64	214	241	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	7.8E-6	214	233	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	216	236	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	1.85E-6	280	318	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.1E-5	294	318	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	8.808	298	318	IPR007087	Zinc finger, C2H2
SMART	SM00355	49	298	318	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009860	Biological Process	pollen tube growth
GO:0010500	Biological Process	transmitting tissue development
GO:1990058	Biological Process	fruit replum development
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 376 aa Download sequence Send to blast
MADPYSNFFS GLLKFNNSPN QNYQHYPASQ QRHFAQTNTF AFNQNQSHHP YYFQYQSSPP 60 SPPLREALPL LSLSPRRHEE EAEEEEEEEE EHHQHSCNIA EAAAAMDVDK NKGKLVEESN 120 LFFSSTSSTA TAALHHEDDD ETTAVTVALH IGLPSPSASE MASLLSSSSE ISGHDHNGDH 180 GGDDSSAGYP FNRLNKGQYW IPTPSQILIG PTQFSCPVCC KTFNRYNNMQ MHMWGHGSQY 240 RKGPESLRGT QPTGMLRLPC YCCAPGCRNN IDHPRAKPLK DFRTLQTHYK RKHGIKPFMC 300 RKCGKAFAVR GDWRTHEKNC GKLWYCICGS DFKHKRSLKD HIKAFGNGHA AYGIDGFEEE 360 DEPASEVEQD NESMQ*

Sequence ? help Back to Top

Protein Sequence Length: 376 aa Download sequence Send to blast

MADPYSNFFS GLLKFNNSPN QNYQHYPASQ QRHFAQTNTF AFNQNQSHHP YYFQYQSSPP  60
SPPLREALPL LSLSPRRHEE EAEEEEEEEE EHHQHSCNIA EAAAAMDVDK NKGKLVEESN  120
LFFSSTSSTA TAALHHEDDD ETTAVTVALH IGLPSPSASE MASLLSSSSE ISGHDHNGDH  180
GGDDSSAGYP FNRLNKGQYW IPTPSQILIG PTQFSCPVCC KTFNRYNNMQ MHMWGHGSQY  240
RKGPESLRGT QPTGMLRLPC YCCAPGCRNN IDHPRAKPLK DFRTLQTHYK RKHGIKPFMC  300
RKCGKAFAVR GDWRTHEKNC GKLWYCICGS DFKHKRSLKD HIKAFGNGHA AYGIDGFEEE  360
DEPASEVEQD NESMQ*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in developing carpels (PubMed:17600712). Expressed in the shoot apical meristem and the replum (PubMed:25039392). {ECO:0000269\|PubMed:17600712}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth. In Arabidopsis, the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization (PubMed:17600712). May play a role in the regulation of AGL8/FUL, which is required for normal pattern of cell division, expansion and differentiation during morphogenesis of the silique (PubMed:23515580). Plays a role in replum development by the activation of the homeobox protein KNAT1 (PubMed:25039392). {ECO:0000269\|PubMed:17600712, ECO:0000269\|PubMed:23515580, ECO:0000269\|PubMed:25039392}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006421457.1	0.0	zinc finger protein WIP2
Swissprot	Q9SVY1	1e-146	ZWIP2_ARATH; Zinc finger protein WIP2
TrEMBL	A0A2H5Q8Z4	0.0	A0A2H5Q8Z4_CITUN; Uncharacterized protein
TrEMBL	V4S330	0.0	V4S330_9ROSI; Uncharacterized protein
STRING	XP_006421457.1	0.0	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM239	28	237

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G57670.1	1e-135	C2H2 family protein

Link Out ? help Back to Top
Phytozome	Ciclev10005189m
Entrez Gene	18031431

Publications ? help Back to Top
Crawford BC, et al. Plant development. Genetic control of distal stem cell fate within root and embryonic meristems. Science, 2015. 347(6222): p. 655-9 [PMID:25612610] Boex-Fontvieille E, et al. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci, 2016. 7: p. 1246 [PMID:27625656]