PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus

Family

bHLH

Protein Properties

Length: 273aa MW: 29901.7 Da PI: 9.2633

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Ciclev10003815m	genome	ICGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	25.9	1.8e-08	180	220	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L Ciclev10003815m 180 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 220 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.434	171	220	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.0E-13	172	230	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	3.27E-14	175	230	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.4E-13	177	226	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	8.2E-6	181	220	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.35E-6	194	225	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 273 aa Download sequence Send to blast
MEFDRLKSAA TEDQMEMMVM MMQMDKFPEF YGACTNNDVA ELLPADHTSA TITTNSNIAS 60 STPHFVDNNS PHIVSSPSFS NMLSNSNTSL NGTSITAAQG TSIPTYFSYS PNERYWRGGA 120 GDSNSSTGVP LSQKQNSMAA MRETIFRVAA MQPIHIDPDS VKPPKRRNVK ISKDPQSVAA 180 RHRRERISER IRILQRLVPG GTKMDTASML DEAIHYVKFL KTQVQSLERA AANRPAGIGF 240 PATLTTGNYP PIIGKEYQQP AVRNGALHYG DA*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed in the developing septum, transmitting tract and stigma. {ECO:0000269\|PubMed:17855426}.
Uniprot	TISSUE SPECIFICITY: Gynoecium. {ECO:0000269\|PubMed:17855426}.

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006434747.1	0.0	transcription factor HEC2
Swissprot	Q9SND4	2e-45	HEC2_ARATH; Transcription factor HEC2
TrEMBL	A0A067H8T1	0.0	A0A067H8T1_CITSI; Uncharacterized protein
TrEMBL	V4T470	0.0	V4T470_9ROSI; Uncharacterized protein
STRING	XP_006434747.1	0.0	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1559	27	91

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	7e-41	bHLH family protein

Link Out ? help Back to Top
Phytozome	Ciclev10003815m
Entrez Gene	18042714

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]