PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus

Family

C2H2

Protein Properties

Length: 267aa MW: 29785.9 Da PI: 9.7104

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Ciclev10003648m	genome	ICGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	18.1	7.3e-06	109	128	1	20
EEETTTTEEESSHHHHHHHH CS zf-C2H2 1 ykCpdCgksFsrksnLkrHi 20 ++C+ C k+F+r nL+ H+ Ciclev10003648m 109 FSCHVCFKTFNRYNNLQMHM 128 89*****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	4.99E-5	103	131	No hit	No description
Gene3D	G3DSA:3.30.160.60	3.0E-4	109	128	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.055	109	136	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	111	131	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009813	Biological Process	flavonoid biosynthetic process
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 267 aa Download sequence Send to blast
METQNLSCHS SNVFAISSTN HIQIEPLNLF PSVTYNSNGG STEPQPSLNQ NRKARNEEKD 60 DVAVALHIGL PNYSHSSTNP SAKGNANVAA AKQYWIPTPE QILIGFTHFS CHVCFKTFNR 120 YNNLQMHMWG HGSQYRKGPE SLKGTQPRAI LGIPCYCCAE GCKNSINHPK AKPLKDFRTL 180 QTHYKRKHGL KPFMCRKCGK FLAVKGDWRT HEKNCGKRWL CVCGSDFKHK RSLKDHIKAF 240 GSGHGPFSRP FDGVEVLDDA SSSLLV*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Developing ovules and young seeds. {ECO:0000269\|PubMed:11782451}.
Uniprot	TISSUE SPECIFICITY: Restricted to the endothelium, the innermost cell layer of the seed coat and detected to a lesser extent in the other cell layers of the testa. {ECO:0000269\|PubMed:11782451}.

Functional Description ? help Back to Top
Source	Description
UniProt	May act as a transcriptional regulator involved in the differentiation of young endothelium. Altered differentiation results in incompetence for pigments synthesis and the lack of condensed tannins in the seed coat (PubMed:21477081). Plays a role in the regulatory network controlling flavonoid accumulation in endothelium cells during seed development (PubMed:21477081). {ECO:0000269\|PubMed:11782451, ECO:0000269\|PubMed:21477081}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006433965.2	0.0	protein TRANSPARENT TESTA 1
Swissprot	Q8VWG3	1e-114	TT1_ARATH; Protein TRANSPARENT TESTA 1
TrEMBL	V4T6Z8	0.0	V4T6Z8_9ROSI; Uncharacterized protein
STRING	XP_006433965.1	0.0	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM239	28	237

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34790.1	1e-116	C2H2 family protein

Link Out ? help Back to Top
Phytozome	Ciclev10003648m
Entrez Gene	18041771

Publications ? help Back to Top
Lian J, et al. Silencing of BnTT1 family genes affects seed flavonoid biosynthesis and alters seed fatty acid composition in Brassica napus. Plant Sci., 2017. 254: p. 32-47 [PMID:27964783]