PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ciclev10001534m
Common NameCICLE_v10001534mg
Organism
Citrus clementina
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus
Family C2H2
Protein Properties Length: 374aa    MW: 42964.7 Da    PI: 6.6735
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ciclev10001534mgenomeICGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H213.70.0001879101323
                      ET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                      C+   Cgk+F +  +L++H   H
  Ciclev10001534m  79 CSyeGCGKTFIDAASLRKHAHIH 101
                      77779**************9877 PP
2zf-C2H216.23.1e-05106130123
                      EEET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                      y+C+   Cgk F ++s LkrH   H
  Ciclev10001534m 106 YQCHyeGCGKKFLDSSKLKRHFLIH 130
                      9********************8877 PP
3zf-C2H222.43.3e-07136160123
                      EEET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                      y+Cp   Cgk Fs   nL++H++tH
  Ciclev10001534m 136 YVCPheGCGKAFSLDFNLRSHMKTH 160
                      99**********************9 PP
4zf-C2H217.89.4e-06166190123
                      EEET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                      + Cp  dCgk++ + + Lk+Hi +H
  Ciclev10001534m 166 HICPypDCGKRYAHEYKLKNHIASH 190
                      679999*****************96 PP
5zf-C2H2130.00031229254123
                      EEET..TTTEEESSHHHHHHHHHH.T CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                      y Cp   C k + + + Lk H+++ H
  Ciclev10001534m 229 YACPyeGCEKAYIHEYKLKLHLKReH 254
                      89*********************999 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.609.3E-1472102IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.004677101IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.07477106IPR007087Zinc finger, C2H2
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
SuperFamilySSF576672.36E-880130No hitNo description
Gene3DG3DSA:3.30.160.603.0E-13103125IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0017106130IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015714.17106135IPR007087Zinc finger, C2H2
PROSITE patternPS000280108130IPR007087Zinc finger, C2H2
SuperFamilySSF576673.16E-14117169No hitNo description
Gene3DG3DSA:3.30.160.602.1E-20126160IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.882136165IPR007087Zinc finger, C2H2
SMARTSM003551.7E-4136160IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280138160IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.5E-9161192IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0028166190IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.473166195IPR007087Zinc finger, C2H2
PROSITE patternPS000280168191IPR007087Zinc finger, C2H2
SuperFamilySSF576671.06E-5224252No hitNo description
Gene3DG3DSA:3.30.160.604.6E-9225251IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.012229254IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.66229259IPR007087Zinc finger, C2H2
PROSITE patternPS000280231254IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 374 aa     Download sequence    Send to blast
METHFTHSYF ERRPIVKSKT PAVKWFREWV PQDIAATGGK CQILRWVNEK TLKALKEKAK  60
EPEAPEPEPE PTTEVLFLCS YEGCGKTFID AASLRKHAHI HGERQYQCHY EGCGKKFLDS  120
SKLKRHFLIH TGERDYVCPH EGCGKAFSLD FNLRSHMKTH SQENYHICPY PDCGKRYAHE  180
YKLKNHIASH HEKNAAMEVP RYATPPERIT KTPKPPAGVY GSASSERPYA CPYEGCEKAY  240
IHEYKLKLHL KREHPGHMSD ENAENATTNA DNEMDEGSDQ DAYAGKRVNG KSQKKSRAKP  300
NLKMPPAKVT QRKSSTPSPA TLNVVRKQQW TPKEEVYEEE DSEETEEDRD NVEDGFRYGE  360
NNEDDDEETE YED*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C6e-34791908119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Rapidly induced following seed germination, especially in tender cotyledons. {ECO:0000269|PubMed:26961720}.
UniprotTISSUE SPECIFICITY: Mostly expressed in flowers, to a lower extent in seedlings, stems and leaves, and, at low levels, in roots and senescent leaves. {ECO:0000269|PubMed:26961720}.
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006431730.10.0zinc finger transcription factor YY1
SwissprotQ2V3L31e-159YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLV4T0R50.0V4T0R5_9ROSI; Uncharacterized protein
STRINGXP_006431730.10.0(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM58592846
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-145C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]