PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Coffeeae; Coffea

Family

HSF

Protein Properties

Length: 442aa MW: 49042.6 Da PI: 4.8621

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cc08_g03200	genome	CGSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	104.4	9.2e-33	1	85	9	102
HHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXXXXXX CS HSF_DNA-bind 9 iledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekikrkks 102 +++d+++++++sws+++nsfvv+d+ efa+++LpkyFkh+nf+SFvRQLn+YgF+kv+ ++ weF+++ F +g+k+ll++i r+k Cc08_g03200 1 MVDDPSTDKIVSWSATNNSFVVWDPPEFARDLLPKYFKHNNFSSFVRQLNTYGFRKVDPDR---------WEFANEGFLRGQKHLLKSISRRKP 85 89**********999*************************************999.........*******************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46785	8.84E-32	1	83	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	5.5E-29	1	83	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Gene3D	G3DSA:1.10.10.10	5.3E-35	1	83	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	2.4E-51	1	83	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.4E-10	32	44	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	33	57	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.4E-10	45	57	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009408	Biological Process	response to heat
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 442 aa Download sequence Send to blast
MVDDPSTDKI VSWSATNNSF VVWDPPEFAR DLLPKYFKHN NFSSFVRQLN TYGFRKVDPD 60 RWEFANEGFL RGQKHLLKSI SRRKPAHGHP QPQQQPHAQS PSVGPCVEVG KFGLEEEVER 120 LKRDKNVLMQ ELVRLRQQQQ TTDGQLQAMV QRLQGMEQRQ QQMMSFLAKA VNSPGFLAQF 180 VQQQSDSGRR ITEGSKKRRL KQDGLSDDHS VVPTDGQIVK YQPMMNEAAK AMLRQLMKVD 240 ASPRLENFSN SSDNFLLSDG STQSTAMDCG NSSNRVSGVT LQEVTPSAGQ PFVPAASSVI 300 GQSASAAISN SHSSTLGATS DLNESNVDIL GTETENGAFM DATSLAANGK LALDIDDEQI 360 EWDSSLLDDM EDLPGSIDPF WEKFLQSPQQ SIETEDLNSS QMEDLSKGSQ IKPVDNGWNR 420 TQHMEQLTEQ MGLLTSEGKK V*

Sequence ? help Back to Top

Protein Sequence Length: 442 aa Download sequence Send to blast

MVDDPSTDKI VSWSATNNSF VVWDPPEFAR DLLPKYFKHN NFSSFVRQLN TYGFRKVDPD  60
RWEFANEGFL RGQKHLLKSI SRRKPAHGHP QPQQQPHAQS PSVGPCVEVG KFGLEEEVER  120
LKRDKNVLMQ ELVRLRQQQQ TTDGQLQAMV QRLQGMEQRQ QQMMSFLAKA VNSPGFLAQF  180
VQQQSDSGRR ITEGSKKRRL KQDGLSDDHS VVPTDGQIVK YQPMMNEAAK AMLRQLMKVD  240
ASPRLENFSN SSDNFLLSDG STQSTAMDCG NSSNRVSGVT LQEVTPSAGQ PFVPAASSVI  300
GQSASAAISN SHSSTLGATS DLNESNVDIL GTETENGAFM DATSLAANGK LALDIDDEQI  360
EWDSSLLDDM EDLPGSIDPF WEKFLQSPQQ SIETEDLNSS QMEDLSKGSQ IKPVDNGWNR  420
TQHMEQLTEQ MGLLTSEGKK V*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	4e-24	1	83	36	129	Heat shock factor protein 1
5d5v_B	4e-24	1	83	36	129	Heat shock factor protein 1
5d5v_D	4e-24	1	83	36	129	Heat shock factor protein 1
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	195	200	KKRRLK

Functional Description ? help Back to Top
Source	Description
UniProt	DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027180723.1	0.0	heat shock factor protein HSF8-like
Swissprot	Q40152	0.0	HSF8_SOLLC; Heat shock factor protein HSF8
TrEMBL	A0A068UXT2	0.0	A0A068UXT2_COFCA; Uncharacterized protein
STRING	XP_009781208.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA6413	19	31

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G16820.2	1e-108	heat shock factor 3

Publications ? help Back to Top
Zhu B, et al. Identification and characterization of a novel heat shock transcription factor gene, GmHsfA1, in soybeans (Glycine max). J. Plant Res., 2006. 119(3): p. 247-56 [PMID:16570125] Cai SY, et al. HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants. J. Pineal Res., 2017. [PMID:28095626] Zhou J, et al. Heat Shock Factor HsfA1a Is Essential for R Gene-Mediated Nematode Resistance and Triggers H2O2 Production1. Plant Physiol., 2018. 176(3): p. 2456-2471 [PMID:29339397]