PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Coffeeae; Coffea

Family

C2H2

Protein Properties

Length: 569aa MW: 63304.8 Da PI: 10.0309

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cc05_g07790	genome	CGSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	15.4	5.3e-05	181	201	3	23
ETTTTEEESSHHHHHHHHHHT CS zf-C2H2 3 CpdCgksFsrksnLkrHirtH 23 C++Cgk F r nL+ H r H Cc05_g07790 181 CEICGKGFQRDQNLQLHRRGH 201 *******************88 PP
2	zf-C2H2	13.2	0.00027	255	277	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k++ +s+ k H +t+ Cc05_g07790 255 WKCEKCSKRYAVQSDWKAHSKTC 277 58*****************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	3.47E-6	178	201	No hit	No description
Gene3D	G3DSA:3.30.160.60	5.1E-5	178	201	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	11.489	179	201	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.076	179	201	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	181	201	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	1.9E-4	243	276	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	3.47E-6	250	275	No hit	No description
SMART	SM00355	130	255	275	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005634	Cellular Component	nucleus
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 569 aa Download sequence Send to blast
MSAGCYVNSD KPTPLPQKTR KEKSKEKLSC RLQLSLFTAS HERIAFYLDR KHTLNSHLSS 60 FTLLLIPITG CHKHIKTQRI LHFSASLVKV DIIAKRLNQA LQKAKDSSED DRGSNLKWFH 120 PNSNRRSESS SSKEEEKPSR NTRQRILPFY IPFLFTFFFD PEAEVIALSP KTLMATNRFL 180 CEICGKGFQR DQNLQLHRRG HNLPWKLKQR TSKEVRKRVY VCPEKSCVHH HPSRALGDLT 240 GIKKHFCRKH GEKKWKCEKC SKRYAVQSDW KAHSKTCGTR EYKCDCGTIF SRRDSFITHR 300 AFCDALAEET ARVTAASNVV AANSINYHFV GASLGPGMGQ HFASMFKPIS TNNETPANPI 360 RQGLSLWMGG HGLSQTQESI GNNNLQEIHH QLNPVVSTSG LVFTTDPFVK LTNNISSLPL 420 SNVAKDGGSQ VISVPSLFST QHQSHQTHST ANMSATALLQ KAAQMGATTT DTSFLGSFGL 480 KCNDSQIQDG NRYCSPYGGT ATSVATALQS SVTDHLSTLN ELQMYPSKRR HIQVDQDSTP 540 TTGGGQTRDF LGVGIQSICH PSSINGWI*

Sequence ? help Back to Top

Protein Sequence Length: 569 aa Download sequence Send to blast

MSAGCYVNSD KPTPLPQKTR KEKSKEKLSC RLQLSLFTAS HERIAFYLDR KHTLNSHLSS  60
FTLLLIPITG CHKHIKTQRI LHFSASLVKV DIIAKRLNQA LQKAKDSSED DRGSNLKWFH  120
PNSNRRSESS SSKEEEKPSR NTRQRILPFY IPFLFTFFFD PEAEVIALSP KTLMATNRFL  180
CEICGKGFQR DQNLQLHRRG HNLPWKLKQR TSKEVRKRVY VCPEKSCVHH HPSRALGDLT  240
GIKKHFCRKH GEKKWKCEKC SKRYAVQSDW KAHSKTCGTR EYKCDCGTIF SRRDSFITHR  300
AFCDALAEET ARVTAASNVV AANSINYHFV GASLGPGMGQ HFASMFKPIS TNNETPANPI  360
RQGLSLWMGG HGLSQTQESI GNNNLQEIHH QLNPVVSTSG LVFTTDPFVK LTNNISSLPL  420
SNVAKDGGSQ VISVPSLFST QHQSHQTHST ANMSATALLQ KAAQMGATTT DTSFLGSFGL  480
KCNDSQIQDG NRYCSPYGGT ATSVATALQS SVTDHLSTLN ELQMYPSKRR HIQVDQDSTP  540
TTGGGQTRDF LGVGIQSICH PSSINGWI*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	3e-36	251	318	3	70	Zinc finger protein JACKDAW
5b3h_F	3e-36	251	318	3	70	Zinc finger protein JACKDAW
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269\|PubMed:17785527, ECO:0000269\|PubMed:21935722, ECO:0000269\|PubMed:24821766, ECO:0000269\|PubMed:25829440}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00125	DAP	Transfer from AT1G03840	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269\|PubMed:21935722}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027062624.1	0.0	zinc finger protein MAGPIE-like
Swissprot	Q9ZWA6	1e-151	IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBL	A0A068V7J8	0.0	A0A068V7J8_COFCA; Uncharacterized protein
STRING	EOX99537	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA103	24	350

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G03840.1	1e-144	C2H2 family protein

Publications ? help Back to Top
Muñoz-Strale D,León G Identification of two highly specific pollen promoters using transcriptomic data. Plant Physiol. Biochem., 2014. 83: p. 292-9 [PMID:25208507] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]