PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella

Family

TALE

Protein Properties

Length: 321aa MW: 36726.5 Da PI: 4.6668

Description

TALE family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Carubv10022064m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	27.6	5e-09	261	293	23	55
SS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS Homeobox 23 rypsaeereeLAkklgLterqVkvWFqNrRake 55 +yp++ ++ LA+++gL+++q+ +WF N+R ++ Carubv10022064m 261 PYPTEGDKIALAEETGLDQKQINNWFINQRKRH 293 8*****************************885 PP
2	ELK	33.6	8.3e-12	213	234	1	22
ELK 1 ELKhqLlrKYsgyLgsLkqEFs 22 +LK+qLlrK++++++sLk EFs Carubv10022064m 213 DLKDQLLRKFGSHISSLKLEFS 234 6********************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM01255	5.7E-20	70	114	IPR005540	KNOX1
Pfam	PF03790	1.1E-19	72	113	IPR005540	KNOX1
SMART	SM01256	1.5E-24	122	173	IPR005541	KNOX2
Pfam	PF03791	9.5E-25	126	172	IPR005541	KNOX2
Pfam	PF03789	7.5E-9	213	234	IPR005539	ELK domain
PROSITE profile	PS51213	9.935	213	233	IPR005539	ELK domain
SMART	SM01188	4.2E-6	213	234	IPR005539	ELK domain
PROSITE profile	PS50071	12.633	233	296	IPR001356	Homeobox domain
SuperFamily	SSF46689	5.13E-19	234	305	IPR009057	Homeodomain-like
SMART	SM00389	1.1E-12	235	300	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	1.1E-27	238	297	IPR009057	Homeodomain-like
CDD	cd00086	2.30E-11	242	297	No hit	No description
Pfam	PF05920	1.6E-17	253	292	IPR008422	Homeobox KN domain
PROSITE pattern	PS00027	0	271	294	IPR017970	Homeobox, conserved site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009723	Biological Process	response to ethylene
GO:0009736	Biological Process	cytokinin-activated signaling pathway
GO:0010094	Biological Process	specification of carpel identity
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 321 aa Download sequence Send to blast
MDRMCGFRST ADYSEKPALM MIPSDYQPLL CSSAGDNRQF VSDELATALS SERPSTAPRI 60 RKPEDNFSLG LIKSKIACHP LYPRLLQTYI DCQKVGAPME ITCILEEIQR ENDVYKKRDA 120 TLMACFGDDP DLDEFMETYC DILVKYKSDL ARPFDEATNF LNKIETQLQN LCIGPVSVTG 180 LSDDGMVSSD EELREDDDNV EAHESQQISN DRDLKDQLLR KFGSHISSLK LEFSKKKKKG 240 KLPREARQAL LDWWSVHYTW PYPTEGDKIA LAEETGLDQK QINNWFINQR KRHWKPSENM 300 PLAMMADSSE LLFTENEKET *

Functional Description ? help Back to Top
Source	Description
UniProt	May play a role in meristem function, and may be involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Carubv10022064m

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006301623.1	0.0	homeobox protein knotted-1-like 2 isoform X1
Swissprot	P46640	0.0	KNAT2_ARATH; Homeobox protein knotted-1-like 2
TrEMBL	R0GFW0	0.0	R0GFW0_9BRAS; Uncharacterized protein
STRING	XP_006301623.1	0.0	(Capsella rubella)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM835	27	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G70510.1	1e-176	KNOTTED-like from Arabidopsis thaliana 2

Link Out ? help Back to Top
Phytozome	Carubv10022064m
Entrez Gene	17895163

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Zhang XL,Yang ZP,Zhang J,Zhang LG Ectopic expression of BraYAB1-702, a member of YABBY gene family in Chinese cabbage, causes leaf curling, inhibition of development of shoot apical meristem and flowering stage delaying in Arabidopsis thaliana. Int J Mol Sci, 2013. 14(7): p. 14872-91 [PMID:23863694] Kuijt SJ, et al. Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX families of transcription factors. Plant Physiol., 2014. 164(4): p. 1952-66 [PMID:24532604] Scofield S,Dewitte W,Murray JA STM sustains stem cell function in the Arabidopsis shoot apical meristem and controls KNOX gene expression independently of the transcriptional repressor AS1. Plant Signal Behav, 2018. [PMID:24776954] Lee JE,Lampugnani ER,Bacic A,Golz JF SEUSS and SEUSS-LIKE 2 coordinate auxin distribution and KNOXI activity during embryogenesis. Plant J., 2014. 80(1): p. 122-35 [PMID:25060324] Machida C,Nakagawa A,Kojima S,Takahashi H,Machida Y The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis. Wiley Interdiscip Rev Dev Biol, 2015 Nov-Dec. 4(6): p. 655-71 [PMID:26108442] Li Z, et al. Transcription factors AS1 and AS2 interact with LHP1 to repress KNOX genes in Arabidopsis. J Integr Plant Biol, 2016. 58(12): p. 959-970 [PMID:27273574] Lozano-Sotomayor P, et al. Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana. Plant J., 2016. 88(3): p. 437-451 [PMID:27402171]