PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Carubv10021491m
Common NameCARUB_v10021491mg
Organism
Capsella rubella
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
Family HD-ZIP
Protein Properties Length: 725aa    MW: 79035 Da    PI: 6.6592
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Carubv10021491mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox61.81e-193388156
                     TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
         Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                     +++ +++t++q+++Le+ F+++++p++++r +L+++lgL  rq+k+WFqNrR++ k
  Carubv10021491m 33 KKRYHRHTAQQIQRLESSFKECPHPDEKQRNQLSRELGLAPRQIKFWFQNRRTQLK 88
                     688999**********************************************9877 PP
2START153.22.2e-482374563206
                      HHHHHHHHHHHHHHC-TT-EEEE...EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEE CS
            START   3 aeeaaqelvkkalaeepgWvkss...esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....kaetle 83 
                      a++a++el+++   +ep+W+k     + +n   +   f++s +      +++ea+r sg+v+m+++ lv  ++d + +W e ++    + +tl+
  Carubv10021491m 237 ALTAMEELLRLLHTNEPLWTKADgcrDVLNLGSYENMFPRSSNrgknhnSRVEASRSSGIVFMNAMALVDMFMDCG-KWAELFPsiiaASKTLA 329
                      789*******************9999888888888888877778888899**************************.*******99999***** PP

                      EECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-E CS
            START  84 vissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehv 170
                      vissg      gal+l + e+ +lsplv+ R+   +Ry++q ++g+w++v vS d +q+++ +s++ R   +pSg+li++++ng+skvtwveh+
  Carubv10021491m 330 VISSGmggtheGALHLLYEEMEVLSPLVAtREICELRYCQQIEQGSWIVVNVSYDLPQFVS-HSQSYR---FPSGCLIQDMPNGYSKVTWVEHI 419
                      *************************************************************.999999...*********************** PP

                      E--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
            START 171 dlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                      + +++ p h+l+r ++++g+a+ga +w+ tlqr ce+
  Carubv10021491m 420 ETEEKEPiHELYREIIHQGIAFGAERWLTTLQRMCER 456
                      ***********************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466894.18E-201490IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.602.5E-221984IPR009057Homeodomain-like
PROSITE profilePS5007118.1553090IPR001356Homeobox domain
SMARTSM003891.6E-183194IPR001356Homeobox domain
CDDcd000862.38E-193391No hitNo description
PfamPF000463.1E-173388IPR001356Homeobox domain
PROSITE patternPS0002706588IPR017970Homeobox, conserved site
PROSITE profilePS5084847.955226459IPR002913START domain
SuperFamilySSF559614.4E-33227458No hitNo description
CDDcd088753.28E-102230455No hitNo description
SMARTSM002342.3E-38235456IPR002913START domain
Gene3DG3DSA:3.30.530.201.1E-6236452IPR023393START-like domain
PfamPF018522.6E-41237456IPR002913START domain
SuperFamilySSF559612.86E-18477712No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 725 aa     Download sequence    Send to blast
MSFVVGVGGS GSGSGGDGGG SQHHDGSETD RKKKRYHRHT AQQIQRLESS FKECPHPDEK  60
QRNQLSRELG LAPRQIKFWF QNRRTQLKAQ HERADNSALK AENDKIRCEN IAIREALKHA  120
ICPSCGGPPV SEDPYFDEQK LRIENAHLRE ELERMSTVAS KYMGRPISQL SSLHPMHISP  180
LDLSMTSLTG CGPCGHGPSL DFDLLPGSSM ALGHNNLHSQ PNLAISDMDK PHMTDMALTA  240
MEELLRLLHT NEPLWTKADG CRDVLNLGSY ENMFPRSSNR GKNHNSRVEA SRSSGIVFMN  300
AMALVDMFMD CGKWAELFPS IIAASKTLAV ISSGMGGTHE GALHLLYEEM EVLSPLVATR  360
EICELRYCQQ IEQGSWIVVN VSYDLPQFVS HSQSYRFPSG CLIQDMPNGY SKVTWVEHIE  420
TEEKEPIHEL YREIIHQGIA FGAERWLTTL QRMCERFASL SVPASSSRDL GGVIPSPEGK  480
RSMMRLAQRM ISNYCLSVSR SNNTRSTVVS ELNEVGIRVT AHKSPEPNGT VLCAATTFWL  540
SNSPQNVFNF LKDERTRPQW DVLSNGNSVQ EVAHISSGSH PGNCISVLRA SNAPHSNNML  600
ILQESSTDSA GALVIYSPVD LAALNIAMSG EDPSYIPLLS SGFAISPDGN GSTSEQGGVG  660
GASTSSGRSS SSGSLITVGF QIMVSNLPSA KLNMESVETV NNLIGTTVHQ IKTALNGPTA  720
STTA*
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCarubv10021491m
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0039790.0BT003979.1 Arabidopsis thaliana clone RAFL15-10-L20 (R20587) putative homeobox protein (At1g73360) mRNA, complete cds.
GenBankBT0049150.0BT004915.1 Arabidopsis thaliana clone U20587 putative homeobox protein (At1g73360) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006301097.10.0homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLR0I7H50.0R0I7H5_9BRAS; Uncharacterized protein
STRINGXP_006301097.10.0(Capsella rubella)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM30042665
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]