PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Carubv10018534m
Common NameCARUB_v10018534mg
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
Family GRAS
Protein Properties Length: 649aa    MW: 70361.6 Da    PI: 5.1675
Description GRAS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Carubv10018534mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1GRAS411.86.1e-1262415871360
             GRAS   1 lvelLlecAeavssgdlelaqalLarlselaspdgdpmqRlaayfteALaarlarsvselykal.ppsetseknsseelaalklfsevsPilkf 93 
                      lv++L++cAeav++++l+la+al++++  la ++  +m+++a+yf+eALa+r++r        l pp+++ +++ s++l++   f+e++P+lkf
  Carubv10018534m 241 LVHALMACAEAVQQNNLTLAEALVKQIGCLAVSQSGAMRKVATYFAEALARRIYR--------LsPPQNQIDHSLSDTLQM--HFYETCPYLKF 324
                      689****************************************************........414444444445555444..4********** PP

             GRAS  94 shltaNqaIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgspesgskeeleetgerLakfAeelgvpfefnvlvakrle 187
                      +h+taNqaIlea++g++rvH+iDf+++qGlQWpaL+qaLa R++gpp +R+Tg+g+p++++++ l+e+g +La++Ae+++v+fe++ +va++l+
  Carubv10018534m 325 AHFTANQAILEAFQGKKRVHVIDFSMNQGLQWPALMQALALREGGPPVFRLTGIGPPAPDNSDHLHEVGCKLAQLAEAIHVEFEYRGFVANSLA 418
                      ********************************************************************************************** PP

             GRAS 188 dleleeLrvkp..gEalaVnlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadhnsesFlerflealeyysalfdsleaklpres 279
                      dl+ ++L+++p   E++aVn+v++lh+ll +++ +e+    vL +vk+++P +++vveqe++hn++ Fl+rf+e+l+yys+lfdsle      s
  Carubv10018534m 419 DLDASMLELRPseVESVAVNSVFELHKLLGRPGGIEK----VLGVVKQIKPVIFTVVEQESNHNGPVFLDRFTESLHYYSTLFDSLEGV---PS 505
                      ***********88899*****************9999....*********************************************998...69 PP

             GRAS 280 eerikvErellgreivnvvacegaerrerhetlekWrerleeaGFkpvplsekaakqaklllrkvk.sdgyrveeesgslvl 360
                      ++++++++++lg++i+n+vaceg +r+erhetl++W +r++++GF p++l+++a kqa++ll+ ++ ++gyrvee++g+l+l
  Carubv10018534m 506 SQDKVMSEVYLGKQICNLVACEGPDRVERHETLSQWGNRFGSSGFAPAHLGSNAFKQASMLLSVFNsGQGYRVEENNGCLIL 587
                      999*****************************************************************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM011297.4E-4145118No hitNo description
PfamPF120412.6E-3545112IPR021914Transcriptional factor DELLA, N-terminal
PROSITE profilePS5098565.712215580IPR005202Transcription factor GRAS
PfamPF035142.1E-123241587IPR005202Transcription factor GRAS
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009723Biological Processresponse to ethylene
GO:0009737Biological Processresponse to abscisic acid
GO:0009867Biological Processjasmonic acid mediated signaling pathway
GO:0009938Biological Processnegative regulation of gibberellic acid mediated signaling pathway
GO:0010187Biological Processnegative regulation of seed germination
GO:0010218Biological Processresponse to far red light
GO:0042176Biological Processregulation of protein catabolic process
GO:0042538Biological Processhyperosmotic salinity response
GO:2000033Biological Processregulation of seed dormancy process
GO:2000377Biological Processregulation of reactive oxygen species metabolic process
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 649 aa     Download sequence    Send to blast
MKRDLHQYQG PNATHGTCSS SSPLPPLSKD KMMMVKEEED GNNMDELLAV LGYKVRSSEM  60
AEVALKLEQL ETMMGNVQED GLSHLATDTV HYNPSELYSW LDNMLTELNP PPPPPPPSSL  120
DPILIDNNSF LCTAGDSSTI TSIGGGFPAS DYDLKVIPGN AIYQQRSQFA IDSSSSSSNQ  180
NKRLKSCSSP DSMVTSTSTT AMQIGGVIGT TVTTTTTTAA AAAESTRSVI LVDSQENGVR  240
LVHALMACAE AVQQNNLTLA EALVKQIGCL AVSQSGAMRK VATYFAEALA RRIYRLSPPQ  300
NQIDHSLSDT LQMHFYETCP YLKFAHFTAN QAILEAFQGK KRVHVIDFSM NQGLQWPALM  360
QALALREGGP PVFRLTGIGP PAPDNSDHLH EVGCKLAQLA EAIHVEFEYR GFVANSLADL  420
DASMLELRPS EVESVAVNSV FELHKLLGRP GGIEKVLGVV KQIKPVIFTV VEQESNHNGP  480
VFLDRFTESL HYYSTLFDSL EGVPSSQDKV MSEVYLGKQI CNLVACEGPD RVERHETLSQ  540
WGNRFGSSGF APAHLGSNAF KQASMLLSVF NSGQGYRVEE NNGCLILETL GGALSQLRCL  600
RWCYGEQQIR SSELPLEADG IGAMGGLVKG RISHSVSHIA GTFVVTDE*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3g_A4e-5523658714365Protein SCARECROW
5b3h_A3e-5523658713364Protein SCARECROW
5b3h_D3e-5523658713364Protein SCARECROW
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression in seeds. Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway. Compared to other DELLA proteins, it is the most sensitive to GA application. No effect of the BOI proteins on its stability. Its activity is probably regulated by other phytohormones such as auxin and ethylene, attenuation of auxin transport delaying its GA-induced degradation. {ECO:0000269|PubMed:11606551, ECO:0000269|PubMed:11606552, ECO:0000269|PubMed:12610625, ECO:0000269|PubMed:14615596, ECO:0000269|PubMed:14973286, ECO:0000269|PubMed:15128937, ECO:0000269|PubMed:16034591, ECO:0000269|PubMed:17933900, ECO:0000269|PubMed:20093430, ECO:0000269|PubMed:9490740}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00611ChIP-seqTransfer from AT2G01570Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCarubv10018534m
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC2546040.0AC254604.1 Capsella rubella clone CAP23-D18, complete sequence.
GenBankAC2546070.0AC254607.1 Capsella rubella clone CAP08-M18, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023638148.10.0DELLA protein RGA
SwissprotQ9SLH30.0RGA_ARATH; DELLA protein RGA
TrEMBLR0FRJ60.0R0FRJ6_9BRAS; Uncharacterized protein
STRINGXP_006292324.10.0(Capsella rubella)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM83728121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G01570.10.0GRAS family protein
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Stewart Lilley JL,Gan Y,Graham IA,Nemhauser JL
    The effects of DELLAs on growth change with developmental stage and brassinosteroid levels.
    Plant J., 2013. 76(1): p. 165-73
    [PMID:23834248]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Oh E, et al.
    Cell elongation is regulated through a central circuit of interacting transcription factors in the Arabidopsis hypocotyl.
    Elife, 2015.
    [PMID:24867218]
  5. Gallego-Giraldo C, et al.
    Role of the gibberellin receptors GID1 during fruit-set in Arabidopsis.
    Plant J., 2014. 79(6): p. 1020-1032
    [PMID:24961590]
  6. Fukazawa J, et al.
    DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis.
    Plant Cell, 2014. 26(7): p. 2920-38
    [PMID:25035403]
  7. Tan L,Rong W,Luo H,Chen Y,He C
    The Xanthomonas campestris effector protein XopDXcc8004 triggers plant disease tolerance by targeting DELLA proteins.
    New Phytol., 2014. 204(3): p. 595-608
    [PMID:25040905]
  8. Urano D,Dong T,Bennetzen JL,Jones AM
    Adaptive evolution of signaling partners.
    Mol. Biol. Evol., 2015. 32(4): p. 998-1007
    [PMID:25568345]
  9. Montenegro-Johnson TD, et al.
    Digital Single-Cell Analysis of Plant Organ Development Using 3DCellAtlas.
    Plant Cell, 2015. 27(4): p. 1018-33
    [PMID:25901089]
  10. Kim SI, et al.
    E3 SUMO ligase AtSIZ1 positively regulates SLY1-mediated GA signalling and plant development.
    Biochem. J., 2015. 469(2): p. 299-314
    [PMID:26008766]
  11. MarĂ­n-de la Rosa N, et al.
    Genome Wide Binding Site Analysis Reveals Transcriptional Coactivation of Cytokinin-Responsive Genes by DELLA Proteins.
    PLoS Genet., 2015. 11(7): p. e1005337
    [PMID:26134422]
  12. Xu F, et al.
    DELLA proteins physically interact with CONSTANS to regulate flowering under long days in Arabidopsis.
    FEBS Lett., 2016. 590(4): p. 541-9
    [PMID:26801684]
  13. Moubayidin L, et al.
    A SCARECROW-based regulatory circuit controls Arabidopsis thaliana meristem size from the root endodermis.
    Planta, 2016. 243(5): p. 1159-68
    [PMID:26848984]
  14. Xie Y,Tan H,Ma Z,Huang J
    DELLA Proteins Promote Anthocyanin Biosynthesis via Sequestering MYBL2 and JAZ Suppressors of the MYB/bHLH/WD40 Complex in Arabidopsis thaliana.
    Mol Plant, 2016. 9(5): p. 711-721
    [PMID:26854848]
  15. Shi H,Wei Y,Wang Q,Reiter RJ,He C
    Melatonin mediates the stabilization of DELLA proteins to repress the floral transition in Arabidopsis.
    J. Pineal Res., 2016. 60(3): p. 373-9
    [PMID:26887824]
  16. Lee SA, et al.
    Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue.
    Mol Plant, 2016. 9(6): p. 870-84
    [PMID:26970019]
  17. Liu B,De Storme N,Geelen D
    Gibberellin Induces Diploid Pollen Formation by Interfering with Meiotic Cytokinesis.
    Plant Physiol., 2017. 173(1): p. 338-353
    [PMID:27621423]
  18. Jiang K, et al.
    Substituted Phthalimide AC94377 Is a Selective Agonist of the Gibberellin Receptor GID1.
    Plant Physiol., 2017. 173(1): p. 825-835
    [PMID:27899534]
  19. Matsuoka K, et al.
    Differential Cellular Control by Cotyledon-Derived Phytohormones Involved in Graft Reunion of Arabidopsis Hypocotyls.
    Plant Cell Physiol., 2016. 57(12): p. 2620-2631
    [PMID:27986917]
  20. Zhang Y, et al.
    GA-DELLA pathway is involved in regulation of nitrogen deficiency-induced anthocyanin accumulation.
    Plant Cell Rep., 2017. 36(4): p. 557-569
    [PMID:28275852]
  21. Zheng H, et al.
    MLK1 and MLK2 Coordinate RGA and CCA1 Activity to Regulate Hypocotyl Elongation in Arabidopsis thaliana.
    Plant Cell, 2018. 30(1): p. 67-82
    [PMID:29255112]
  22. Yamazaki K, et al.
    Suppression of DELLA signaling induces procambial cell formation in culture.
    Plant J., 2018. 94(1): p. 48-59
    [PMID:29383774]
  23. Liu B,De Storme N,Geelen D
    Cold-Induced Male Meiotic Restitution in Arabidopsis thaliana Is Not Mediated by GA-DELLA Signaling.
    Front Plant Sci, 2018. 9: p. 91
    [PMID:29459879]
  24. Kumar A,Singh A,Panigrahy M,Sahoo PK,Panigrahi KCS
    Carbon nanoparticles influence photomorphogenesis and flowering time in Arabidopsis thaliana.
    Plant Cell Rep., 2018. 37(6): p. 901-912
    [PMID:29541883]
  25. Zhang Y, et al.
    DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6.
    Plant Cell Rep., 2018. 37(7): p. 981-992
    [PMID:29574486]