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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
Carubv10013821m |
| Common Name | CARUB_v10013821mg |
| Organism |
|
| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
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| Family |
bHLH |
| Protein Properties |
Length: 415aa MW: 46299.5 Da PI: 4.9506 |
| Description |
bHLH family protein |
| Gene Model |
| Gene Model ID |
Type |
Source |
Coding Sequence |
| Carubv10013821m | genome | JGI | View CDS |
|
| Signature Domain? help Back to Top |
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| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | HLH | 38 | 2.9e-12 | 197 | 248 | 1 | 55 |
CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
HLH 1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55
+r++h ++Er+RR+++N+ + Lr+l+P + + ++ + a+i A+e++++L+
Carubv10013821m 197 QRMTHIAVERNRRKQMNEHLRVLRSLMPGS---YVQRGDQASIIGGAIEFVRELE 248
79****************************...9*****************9995 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0010377 | Biological Process | guard cell fate commitment |
| GO:0045597 | Biological Process | positive regulation of cell differentiation |
| GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated |
| GO:0051782 | Biological Process | negative regulation of cell division |
| GO:0005634 | Cellular Component | nucleus |
| GO:0046983 | Molecular Function | protein dimerization activity |
| Sequence ? help Back to Top |
| Protein Sequence Length: 415 aa
Download sequence Send
to blast |
MDKDYSAPNF LGESSGGNED NSSGMIDYMF NRNLQQQQKQ SMPQQQQHQL SPTGFGTTPS 60
FDKMNFADVM QFADFGPKLA LNQTRNQEDQ ESGIDPVYFL KFPVLNDKIE EHNQTQHLMP 120
SHQTSQEGGE CGGNIGNVFL EEQDDQDDDN DNNSVQLRFI GGGEEEDREN KNVTTKEVKS 180
KRKRARTSKT SEEVESQRMT HIAVERNRRK QMNEHLRVLR SLMPGSYVQR GDQASIIGGA 240
IEFVRELEQL LQCLESQKRR RILGETGRDM TTTTTSSSPI AAVANQAQPL IINGNVTELE 300
GGGGLREETA ENKSCLADVE VKLLGFDAMI KILSRRRPGQ LIKTIAALED LHLSILHTNI 360
TTMEQTVLYS FNVKITSETR FTAEDIASSI QQIFSFIHAN TNISGSSNLG NVFA*
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| Nucleic Localization
Signal ? help
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| No. |
Start |
End |
Sequence |
| 1 | 197 | 208 | RMTHIAVERNRR |
| 2 | 257 | 261 | KRRRI |
| Functional Description ? help
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| Source |
Description |
| UniProt | Transcription activator (PubMed:17088607, PubMed:17183265, PubMed:17183267). Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata (PubMed:17088607, PubMed:17183265, PubMed:17183267). Prevents histone H3K27me3 marks and derepresses stem cell gene expression (PubMed:24654956). {ECO:0000269|PubMed:17088607, ECO:0000269|PubMed:17183265, ECO:0000269|PubMed:17183267, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24654956}. |
| Regulation -- Description ? help
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| Source |
Description |
| UniProt | INDUCTION: Inhibited by low relative humidity (LRH) via epigenetic CG methylation, thus leading to a reduced stomatal index. {ECO:0000269|PubMed:22442411}. |
| Annotation --
Nucleotide ? help
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| Source |
Hit ID |
E-value |
Description |
| GenBank | AK221324 | 0.0 | AK221324.1 Arabidopsis thaliana mRNA for putative bHLH transcription factor, complete cds, clone: RAFL25-14-O10. |
| GenBank | BT028961 | 0.0 | BT028961.1 Arabidopsis thaliana At3g24140 mRNA, complete cds. |
| Publications
? help Back to Top |
- Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
Differentiation, 2010. 80(1): p. 1-8
[PMID:20219281] - Matos JL, et al.
Irreversible fate commitment in the Arabidopsis stomatal lineage requires a FAMA and RETINOBLASTOMA-RELATED module.
Elife, 2015.
[PMID:25303364] - Chen L, et al.
NRPB3, the third largest subunit of RNA polymerase II, is essential for stomatal patterning and differentiation in Arabidopsis.
Development, 2016. 143(9): p. 1600-11
[PMID:26989174] - Lee JH,Jung JH,Park CM
Light Inhibits COP1-Mediated Degradation of ICE Transcription Factors to Induce Stomatal Development in Arabidopsis.
Plant Cell, 2017. 29(11): p. 2817-2830
[PMID:29070509] - Han X, et al.
Jasmonate Negatively Regulates Stomatal Development in Arabidopsis Cotyledons.
Plant Physiol., 2018. 176(4): p. 2871-2885
[PMID:29496884] - Li X,Yang R,Chen H
The Arabidopsis thaliana Mediator subunit MED8 regulates plant immunity to Botrytis Cinerea through interacting with the basic helix-loop-helix (bHLH) transcription factor FAMA.
PLoS ONE, 2018. 13(3): p. e0193458
[PMID:29513733]
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