PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Carubv10005408m

Common Name

CARUB_v10005408mg

Organism

Capsella rubella

Taxonomic ID

81985

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella

Family

HSF

Protein Properties

Length: 289aa MW: 31737.3 Da PI: 6.4129

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Carubv10005408m	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	114.5	6.7e-36	15	106	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkelle 95 Fl+k+y++++d+++++++sw+e+g++fvv+++ ef+k++Lp+yFkh+nf+SF+RQLn+YgF+k+ ++ weF++++F++g ++ll+ Carubv10005408m 15 FLSKTYQLVDDHNTDDVVSWNEEGTAFVVWKTAEFSKDLLPQYFKHNNFSSFIRQLNTYGFRKTVPDK---------WEFANDNFRRGGEDLLS 99 9*************************************************************9999.........************* PP XXXXXXX CS HSF_DNA-bind 96 kikrkks 102 +i+r+ks Carubv10005408m 100 EIRRRKS 106 **986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.2E-37	6	98	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	3.7E-57	11	104	IPR000232	Heat shock factor (HSF)-type, DNA-binding
SuperFamily	SSF46785	5.3E-33	12	104	IPR011991	Winged helix-turn-helix DNA-binding domain
PRINTS	PR00056	4.6E-20	15	38	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	3.6E-32	15	104	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	4.6E-20	53	65	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	4.6E-20	66	78	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009408	Biological Process	response to heat
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 289 aa Download sequence Send to blast
MTAVTAAQRS VPAPFLSKTY QLVDDHNTDD VVSWNEEGTA FVVWKTAEFS KDLLPQYFKH 60 NNFSSFIRQL NTYGFRKTVP DKWEFANDNF RRGGEDLLSE IRRRKSVIAA AGKCVVVGGS 120 PSESNSGGDG GDHGSSSTSS PGSSKNPGSV ENMVADLSGE NEKLKRENNS LSSELAAAKK 180 QRDELVTFLT DHLKVKPEQI EKMIKGGKFK PVESEEGEES DCEGCHGGGE REEEGVGEGL 240 KLFGVWLKGE RKKRGRDEKN YVVAGSHMTE IKNVDFHAPL WKSSKVCN*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	5e-24	5	104	20	129	Heat shock factor protein 1
5d5v_B	5e-24	5	104	20	129	Heat shock factor protein 1
5d5v_D	5e-24	5	104	20	129	Heat shock factor protein 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Carubv10005408m

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat stress. {ECO:0000269\|PubMed:9645433}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY120760	0.0	AY120760.1 Arabidopsis thaliana heat shock transcription factor HSF4 (At4g36990) mRNA, complete cds.
GenBank	BT003369	0.0	BT003369.1 Arabidopsis thaliana heat shock transcription factor HSF4 (At4g36990) mRNA, complete cds.
GenBank	Y14069	0.0	Y14069.1 Arabidopsis thaliana mRNA for heat shock factor 4.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006284246.1	0.0	heat stress transcription factor B-1
Swissprot	Q96320	1e-166	HSFB1_ARATH; Heat stress transcription factor B-1
TrEMBL	R0GJT2	0.0	R0GJT2_9BRAS; Uncharacterized protein
STRING	XP_006284246.1	0.0	(Capsella rubella)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6101	25	46

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36990.1	1e-139	heat shock factor 4

Link Out ? help Back to Top
Phytozome	Carubv10005408m
Entrez Gene	17880081

Publications ? help Back to Top
Weng M, et al. Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana. Plant Cell Environ., 2014. 37(9): p. 2128-38 [PMID:24548003] Nagashima Y,Iwata Y,Ashida M,Mishiba K,Koizumi N Exogenous salicylic acid activates two signaling arms of the unfolded protein response in Arabidopsis. Plant Cell Physiol., 2014. 55(10): p. 1772-8 [PMID:25138441] Nie S,Yue H,Xing D A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance. Plant Physiol., 2016. [PMID:26099269] Hossain MA, et al. Identification of Novel Components of the Unfolded Protein Response in Arabidopsis. Front Plant Sci, 2016. 7: p. 650 [PMID:27242851] Röth S,Mirus O,Bublak D,Scharf KD,Schleiff E DNA-binding and repressor function are prerequisites for the turnover of the tomato heat stress transcription factor HsfB1. Plant J., 2017. 89(1): p. 31-44 [PMID:27560701] Xu G, et al. uORF-mediated translation allows engineered plant disease resistance without fitness costs. Nature, 2017. 545(7655): p. 491-494 [PMID:28514448]