PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella

Family

MYB

Protein Properties

Length: 507aa MW: 56340.6 Da PI: 7.4972

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cagra.2515s0028.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	50.4	5e-16	80	126	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g WT+eEde l +av + g++Wk+Ia+ ++ Rt+ qc +rwqk+l Cagra.2515s0028.1.p 80 KGGWTPEEDETLRRAVGTFKGKSWKKIAEFFN-DRTEVQCLHRWQKVL 126 688***************************.**********986 PP
2	Myb_DNA-binding	58.7	1.3e-18	132	178	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT+eEde++v++v+++G+ W+ Ia+ + gR +kqc++rw+++l Cagra.2515s0028.1.p 132 KGPWTQEEDEKIVELVEKYGPAKWSVIAQSLT-GRIGKQCRERWHNHL 178 79***************************9.***********97 PP
3	Myb_DNA-binding	53	8e-17	184	227	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 +++WT+eE++ l +a++ +G++ W+ Ia+ + gRt++ +k++w++ Cagra.2515s0028.1.p 184 KDAWTAEEELALMNAHRIHGNK-WAEIAKVLH-GRTDNAIKNHWNS 227 679*****************.*****.*********96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	15.173	75	126	IPR017930	Myb domain
SMART	SM00717	5.4E-14	79	128	IPR001005	SANT/Myb domain
Pfam	PF00249	8.2E-15	80	126	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	1.79E-15	81	136	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	6.5E-22	82	138	IPR009057	Homeodomain-like
CDD	cd00167	2.23E-12	83	126	No hit	No description
PROSITE profile	PS51294	30.49	127	182	IPR017930	Myb domain
SuperFamily	SSF46689	7.49E-32	129	225	IPR009057	Homeodomain-like
SMART	SM00717	5.2E-17	131	180	IPR001005	SANT/Myb domain
CDD	cd00167	8.08E-15	134	178	No hit	No description
Pfam	PF13921	8.0E-18	135	193	No hit	No description
Gene3D	G3DSA:1.10.10.60	3.6E-27	139	185	IPR009057	Homeodomain-like
PROSITE profile	PS51294	21.104	183	233	IPR017930	Myb domain
SMART	SM00717	2.4E-15	183	231	IPR001005	SANT/Myb domain
CDD	cd00167	9.90E-12	186	229	No hit	No description
Gene3D	G3DSA:1.10.10.60	2.1E-22	186	232	IPR009057	Homeodomain-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 507 aa Download sequence Send to blast
MSCSLNPAAA SPDEMDIQEE TGEVKIEGQC VENKQSTPAS CSSLSEGSAG SSHKSPPTVA 60 SPATASPAHR RTSGPIRRAK GGWTPEEDET LRRAVGTFKG KSWKKIAEFF NDRTEVQCLH 120 RWQKVLNPDL IKGPWTQEED EKIVELVEKY GPAKWSVIAQ SLTGRIGKQC RERWHNHLNP 180 DINKDAWTAE EELALMNAHR IHGNKWAEIA KVLHGRTDNA IKNHWNSSLK KKSEFYLSTG 240 RLPPPTTAKH GVPDSVTKRS LSAQKRGSDS VTQTPSRTTD LKNPDEDGNG QSNSCVPLEE 300 RVAASRMTGV NEYAYSPQCV NPEPLPETGG VAMNGYRLYY KPQIEYYMAS EADTQRMYGH 360 ECGCSPIASP VSFFTPPPCR NEYSNGSAPR SPESFLREAA RTYPNTPSIF RKRRPRVVIP 420 DNNDATKTAE VRKVDQKVDD GKDSSENPVS EEVQNNGSNA YNLSPPYRIR SKRTAVFKSR 480 QLEFISAEEE KADDETKSAE KDMLLD*

Sequence ? help Back to Top

Protein Sequence Length: 507 aa Download sequence Send to blast

MSCSLNPAAA SPDEMDIQEE TGEVKIEGQC VENKQSTPAS CSSLSEGSAG SSHKSPPTVA  60
SPATASPAHR RTSGPIRRAK GGWTPEEDET LRRAVGTFKG KSWKKIAEFF NDRTEVQCLH  120
RWQKVLNPDL IKGPWTQEED EKIVELVEKY GPAKWSVIAQ SLTGRIGKQC RERWHNHLNP  180
DINKDAWTAE EELALMNAHR IHGNKWAEIA KVLHGRTDNA IKNHWNSSLK KKSEFYLSTG  240
RLPPPTTAKH GVPDSVTKRS LSAQKRGSDS VTQTPSRTTD LKNPDEDGNG QSNSCVPLEE  300
RVAASRMTGV NEYAYSPQCV NPEPLPETGG VAMNGYRLYY KPQIEYYMAS EADTQRMYGH  360
ECGCSPIASP VSFFTPPPCR NEYSNGSAPR SPESFLREAA RTYPNTPSIF RKRRPRVVIP  420
DNNDATKTAE VRKVDQKVDD GKDSSENPVS EEVQNNGSNA YNLSPPYRIR SKRTAVFKSR  480
QLEFISAEEE KADDETKSAE KDMLLD*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h88_C	8e-67	79	232	5	158	MYB PROTO-ONCOGENE PROTEIN
1h89_C	8e-67	79	232	5	158	MYB PROTO-ONCOGENE PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). {ECO:0000250\|UniProtKB:Q94FL9, ECO:0000269\|PubMed:26069325}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Cagra.2515s0028.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Slightly induced by ethylene, auxin (IAA), jasmonic acid (JA) and salicylic acid (SA). {ECO:0000269\|PubMed:16463103}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY142649	0.0	AY142649.1 Arabidopsis thaliana putative MYB family transcription factor (At3g09370) mRNA, complete cds.
GenBank	AY519651	0.0	AY519651.1 Arabidopsis thaliana MYB transcription factor (At3g09370) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006297357.2	0.0	transcription factor MYB3R-3 isoform X2
Swissprot	Q8H1P9	0.0	MB3R3_ARATH; Transcription factor MYB3R-3
TrEMBL	R0HXM6	0.0	R0HXM6_9BRAS; Uncharacterized protein (Fragment)
STRING	Cagra.2515s0028.1.p	0.0	(Capsella grandiflora)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1667	28	87

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G09370.2	0.0	myb domain protein 3r-3

Link Out ? help Back to Top
Phytozome	Cagra.2515s0028.1.p

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325] Chen P, et al. Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage. Nat Commun, 2017. 8(1): p. 635 [PMID:28935922]