PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella

Family

HSF

Protein Properties

Length: 272aa MW: 31635.8 Da PI: 6.5174

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cagra.1043s0019.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	109.5	2.5e-34	28	118	2	101
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkk 91 Fl+k++e+++d+++++++sw++ g+sfvv+d ++f++ +Lp++Fkhsnf+SF+RQLn+YgF+k++ e+ weF+++ F g++ Cagra.1043s0019.1.p 28 FLTKTFEMVDDPNTDQIVSWNRGGTSFVVWDLHSFSTVLLPRHFKHSNFSSFIRQLNTYGFRKIEAER---------WEFANEGFLVGQR 108 9**************************************************************999.........********* PP XXXXXXXXXX CS HSF_DNA-bind 92 ellekikrkk 101 +ll++ikr++ Cagra.1043s0019.1.p 109 QLLKHIKRRA 118 ******97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00415	1.0E-56	24	117	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Gene3D	G3DSA:1.10.10.10	1.3E-36	24	117	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	9.79E-34	24	117	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	2.6E-30	28	117	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.6E-19	28	51	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.6E-19	66	78	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	67	91	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	1.6E-19	79	91	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009408	Biological Process	response to heat
GO:0009644	Biological Process	response to high light intensity
GO:0032268	Biological Process	regulation of cellular protein metabolic process
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 272 aa Download sequence Send to blast
MNPFVPEGVD HQLPQPMEGL HEVGPPPFLT KTFEMVDDPN TDQIVSWNRG GTSFVVWDLH 60 SFSTVLLPRH FKHSNFSSFI RQLNTYGFRK IEAERWEFAN EGFLVGQRQL LKHIKRRATF 120 TSSTPSSHDA CNELRREKQV LMLELMSLRQ QHQTTKSYIK AMEQRIEGAE KKQRHMMSFL 180 ARAMQNPSFL HQLLKQRDKR IMEIEDETAK RKRGSSSMSE LEALALEMQG YGKQRNMLEE 240 EDHHLVEERE LDDGFWEELL SDESLSLAST S*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ldu_A	8e-25	26	122	18	125	Heat shock factor protein 1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	110	116	LKHIKRR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Cagra.1043s0019.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023638472.1	0.0	heat stress transcription factor A-7a
Swissprot	Q9SV12	1e-167	HFA7A_ARATH; Heat stress transcription factor A-7a
TrEMBL	D7LTZ9	1e-165	D7LTZ9_ARALL; AT-HSFA7A
STRING	Cagra.1043s0019.1.p	0.0	(Capsella grandiflora)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1256	28	99

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G51910.1	1e-139	heat shock transcription factor A7A

Link Out ? help Back to Top
Phytozome	Cagra.1043s0019.1.p

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Guan Q,Yue X,Zeng H,Zhu J The protein phosphatase RCF2 and its interacting partner NAC019 are critical for heat stress-responsive gene regulation and thermotolerance in Arabidopsis. Plant Cell, 2014. 26(1): p. 438-53 [PMID:24415771] Nie S,Yue H,Xing D A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance. Plant Physiol., 2016. [PMID:26099269]