PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella

Family

MYB

Protein Properties

Length: 545aa MW: 60618.8 Da PI: 6.9195

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cagra.0487s0012.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	57.6	2.8e-18	75	121	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g WT+eEde l +av+++ g++Wk+Ia+ ++ Rt+ qc +rwqk+l Cagra.0487s0012.1.p 75 KGGWTPEEDETLRRAVEKYKGKRWKKIAEFFP-DRTEVQCLHRWQKVL 121 688***************************.**********986 PP
2	Myb_DNA-binding	61.9	1.3e-19	127	173	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT+eEd+++v++vk++G+ W+ Ia+ ++ gR +kqc++rw+++l Cagra.0487s0012.1.p 127 KGPWTQEEDDKIVELVKKYGPAKWSVIAKSLP-GRIGKQCRERWHNHL 173 79****************************.***********97 PP
3	Myb_DNA-binding	51.2	2.9e-16	179	222	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 +++WT eE+ l +a++ +G++ W+ Ia+ ++ gRt++ +k++w++ Cagra.0487s0012.1.p 179 KDAWTIEEESALMNAHRIYGNK-WAEIAKVLP-GRTDNAIKNHWNS 222 679*****************.*****.*********96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	18.856	70	121	IPR017930	Myb domain
SMART	SM00717	5.7E-17	74	123	IPR001005	SANT/Myb domain
Pfam	PF00249	7.5E-17	75	121	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	1.72E-16	76	131	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	5.2E-24	77	129	IPR009057	Homeodomain-like
CDD	cd00167	4.17E-15	78	121	No hit	No description
PROSITE profile	PS51294	31.779	122	177	IPR017930	Myb domain
SuperFamily	SSF46689	5.5E-32	124	220	IPR009057	Homeodomain-like
SMART	SM00717	3.9E-18	126	175	IPR001005	SANT/Myb domain
Pfam	PF00249	2.3E-18	127	173	IPR001005	SANT/Myb domain
CDD	cd00167	1.45E-15	129	173	No hit	No description
Gene3D	G3DSA:1.10.10.60	2.0E-27	130	176	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	8.8E-23	177	228	IPR009057	Homeodomain-like
PROSITE profile	PS51294	22.361	178	228	IPR017930	Myb domain
SMART	SM00717	1.4E-14	178	226	IPR001005	SANT/Myb domain
Pfam	PF00249	2.3E-14	179	222	IPR001005	SANT/Myb domain
CDD	cd00167	3.05E-11	181	224	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 545 aa Download sequence Send to blast
MSSSSNPAAC SPVKEELSEL QTEIQCMENK QPLAASCSSA SEGSGCFFLK SPEIATPATS 60 SPTPRRTSGP MRRAKGGWTP EEDETLRRAV EKYKGKRWKK IAEFFPDRTE VQCLHRWQKV 120 LNPELVKGPW TQEEDDKIVE LVKKYGPAKW SVIAKSLPGR IGKQCRERWH NHLNPDIRKD 180 AWTIEEESAL MNAHRIYGNK WAEIAKVLPG RTDNAIKNHW NSSLKKKLEF YLATGNLPPP 240 ATKFSVLNDI ADGDRDSKQS SATKPFKDSD SIAQTSSGNT DSNEVGKDHI DASSALLEEV 300 AASRRISVNE YACSPVEHKP RLPNLEPISE EVRINSRAYV ERSIQRKEEN GFGTPKHGNL 360 YYKSPLDYYF PSEADLQRMS GSECGCSPES ATPVSLITPP CNKDSGLAAT RSPESFLREA 420 ARTFPNTPSI FRKRRKVVLA AKTDDAVVNV GVKEAEQKEE SKDSSDISPA GRESLLLETT 480 DDCRDDEKLE SNGNVINVSP PYRLRAKRTA GMKSRQLEFT SAKENQPDNE TETSELASEE 540 DKPL*

Sequence ? help Back to Top

Protein Sequence Length: 545 aa Download sequence Send to blast

MSSSSNPAAC SPVKEELSEL QTEIQCMENK QPLAASCSSA SEGSGCFFLK SPEIATPATS  60
SPTPRRTSGP MRRAKGGWTP EEDETLRRAV EKYKGKRWKK IAEFFPDRTE VQCLHRWQKV  120
LNPELVKGPW TQEEDDKIVE LVKKYGPAKW SVIAKSLPGR IGKQCRERWH NHLNPDIRKD  180
AWTIEEESAL MNAHRIYGNK WAEIAKVLPG RTDNAIKNHW NSSLKKKLEF YLATGNLPPP  240
ATKFSVLNDI ADGDRDSKQS SATKPFKDSD SIAQTSSGNT DSNEVGKDHI DASSALLEEV  300
AASRRISVNE YACSPVEHKP RLPNLEPISE EVRINSRAYV ERSIQRKEEN GFGTPKHGNL  360
YYKSPLDYYF PSEADLQRMS GSECGCSPES ATPVSLITPP CNKDSGLAAT RSPESFLREA  420
ARTFPNTPSI FRKRRKVVLA AKTDDAVVNV GVKEAEQKEE SKDSSDISPA GRESLLLETT  480
DDCRDDEKLE SNGNVINVSP PYRLRAKRTA GMKSRQLEFT SAKENQPDNE TETSELASEE  540
DKPL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h88_C	5e-72	74	228	5	159	MYB PROTO-ONCOGENE PROTEIN
1h89_C	5e-72	74	228	5	159	MYB PROTO-ONCOGENE PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). {ECO:0000250\|UniProtKB:Q94FL9, ECO:0000269\|PubMed:26069325}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00482	DAP	Transfer from AT5G02320	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Cagra.0487s0012.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Slightly induced by ethylene and salicylic acid (SA). {ECO:0000269\|PubMed:16463103}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY519649	0.0	AY519649.1 Arabidopsis thaliana MYB transcription factor (At5g02320) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006287439.1	0.0	transcription factor MYB3R-5
Swissprot	Q6R032	0.0	MB3R5_ARATH; Transcription factor MYB3R-5
TrEMBL	R0FDT2	0.0	R0FDT2_9BRAS; Uncharacterized protein
STRING	Cagra.0487s0012.1.p	0.0	(Capsella grandiflora)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1667	28	87

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G02320.2	0.0	myb domain protein 3r-5

Link Out ? help Back to Top
Phytozome	Cagra.0487s0012.1.p

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325] Chen P, et al. Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage. Nat Commun, 2017. 8(1): p. 635 [PMID:28935922]