PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella

Family

MIKC_MADS

Protein Properties

Length: 276aa MW: 31483.4 Da PI: 9.4504

Description

MIKC_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cagra.0447s0009.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	96.5	1.1e-30	9	59	1	51
S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS SRF-TF 1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51 krienk+nrqvtf+kRrng+lKKA+ELSvLCdae+a++ifs++gklye++s Cagra.0447s0009.1.p 9 KRIENKINRQVTFAKRRNGLLKKAYELSVLCDAEIALLIFSNRGKLYEFCS 59 79***********************************************96 PP
2	K-box	87.5	2.5e-29	82	174	8	100
K-box 8 sleeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkk 97 ++++++ + +q++ kLk+++enLq++qRhllGe+L ++ ++eL+qLe+q++ sl++iRs+K + +l+q+++l+ ke++l e+n++Lrkk Cagra.0447s0009.1.p 82 NQSAKDLQDKYQDYLKLKSRVENLQHSQRHLLGEELAEMGVNELEQLERQVDASLRQIRSTKARSMLDQLSDLKTKEEMLLETNRDLRKK 171 36788999********************************************************************************** PP K-box 98 lee 100 lee Cagra.0447s0009.1.p 172 LEE 174 987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50066	33.137	1	61	IPR002100	Transcription factor, MADS-box
SMART	SM00432	1.0E-41	1	60	IPR002100	Transcription factor, MADS-box
CDD	cd00265	2.49E-43	2	77	No hit	No description
SuperFamily	SSF55455	2.88E-32	2	79	IPR002100	Transcription factor, MADS-box
PROSITE pattern	PS00350	0	3	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	1.7E-32	3	23	IPR002100	Transcription factor, MADS-box
Pfam	PF00319	2.0E-25	10	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	1.7E-32	23	38	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	1.7E-32	38	59	IPR002100	Transcription factor, MADS-box
Pfam	PF01486	1.2E-24	86	172	IPR002487	Transcription factor, K-box
PROSITE profile	PS51297	14.873	88	178	IPR002487	Transcription factor, K-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010076	Biological Process	maintenance of floral meristem identity
GO:0048440	Biological Process	carpel development
GO:0048441	Biological Process	petal development
GO:0048442	Biological Process	sepal development
GO:0048443	Biological Process	stamen development
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 276 aa Download sequence Send to blast
MGRGKVELKR IENKINRQVT FAKRRNGLLK KAYELSVLCD AEIALLIFSN RGKLYEFCSS 60 PSGMAKTVDK YRKHSYATMD PNQSAKDLQD KYQDYLKLKS RVENLQHSQR HLLGEELAEM 120 GVNELEQLER QVDASLRQIR STKARSMLDQ LSDLKTKEEM LLETNRDLRK KLEESDAALT 180 QSVWGASAAE HSQQLQQQQQ LQQQQQQQQH QQQQGMSSYQ PNPPIQEAGF FKPLQGNVAL 240 QMSSHYNHNH AAMTNANNSA TTSQNVNGFF PGWMV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4ox0_A	2e-22	93	172	22	101	Developmental protein SEPALLATA 3
4ox0_B	2e-22	93	172	22	101	Developmental protein SEPALLATA 3
4ox0_C	2e-22	93	172	22	101	Developmental protein SEPALLATA 3
4ox0_D	2e-22	93	172	22	101	Developmental protein SEPALLATA 3
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that binds specifically to the CArG box DNA sequence 5'-CC (A/T)6 GG-3' (PubMed:7632923, PubMed:25183521). Plays an important role in the determination of flower meristem identity. Involved in the specification of sepal identity. Contributes to the development of petals, stamens and carpels (PubMed:15530395). {ECO:0000269\|PubMed:15530395, ECO:0000269\|PubMed:25183521, ECO:0000269\|PubMed:7632923}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00030	SELEX	Transfer from AT2G03710	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Cagra.0447s0009.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	ATU81369	0.0	U81369.1 Arabidopsis thaliana MADS box protein (AGL3) mRNA, complete cds.
GenBank	AY063894	0.0	AY063894.1 Arabidopsis thaliana putative MADS-box protein AGL3 (At2g03710) mRNA, complete cds.
GenBank	AY096386	0.0	AY096386.1 Arabidopsis thaliana putative MADS-box protein (AGL3) (At2g03710) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006291635.1	0.0	agamous-like MADS-box protein AGL3 isoform X1
Swissprot	P29383	1e-172	AGL3_ARATH; Agamous-like MADS-box protein AGL3
TrEMBL	R0HKZ0	0.0	R0HKZ0_9BRAS; Uncharacterized protein
STRING	Cagra.0447s0009.1.p	0.0	(Capsella grandiflora)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM7135	24	40

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G03710.1	1e-157	MIKC_MADS family protein

Link Out ? help Back to Top
Phytozome	Cagra.0447s0009.1.p

Publications ? help Back to Top
Maejima K, et al. Degradation of class E MADS-domain transcription factors in Arabidopsis by a phytoplasmal effector, phyllogen. Plant Signal Behav, 2015. 10(8): p. e1042635 [PMID:26179462]