PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

CCG007427.1

Organism

Populus euphratica

Taxonomic ID

75702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus

Family

bHLH

Protein Properties

Length: 409aa MW: 46755.7 Da PI: 4.8618

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
CCG007427.1	genome	LZU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	32.1	2e-10	211	261	1	54
CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +r++h ++Er+RR+++N+ + Lr+ +P + + ++ + a+i A+ ++++L CCG007427.1 211 QRMTHIAVERNRRKQMNEHLRVLRSFMPGS---YVQRGDQASIIGGAIVFVREL 261 79*************************9...9************999988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:4.10.280.10	1.2E-11	209	265	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	6.89E-11	209	266	No hit	No description
SuperFamily	SSF47459	1.96E-15	210	287	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	14.278	210	261	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	9.9E-8	211	261	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.7E-7	216	267	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd04873	0.0031	335	377	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 409 aa Download sequence Send to blast
MLFCFELDYL QASFAGLDYS LDHHLHQPPQ HHELMKPRIA ETSGDDDSNT GMIYYMLNNP 60 HQPQMSPGFC TSTSFDKLSF ADVMQFADFG PKLALNQTKI SEEEIGIDPV YFLKFPVLNE 120 KIEEQSLMVP QLGGENDERF TGVSSDEHRE GMVGEEGGVR EDEEARLWDN NSVQLQFLGD 180 QDLQNKNPIP EGKNKRKRPR TIKTSEEVES QRMTHIAVER NRRKQMNEHL RVLRSFMPGS 240 YVQRGDQASI IGGAIVFVRE LEQLLQCLES QKRQRLMEDS ALAIQQPHRP FFPPMPQPND 300 QMKTLDLETE LREETAENKS CLADVEVKLL GFDAMIKILS RRRPGQLIET IAALEDLQLN 360 IHHTSITTIE QTVLYSFNAK IESESRFTAE DIASSVQHAF TFIHANSSM

Sequence ? help Back to Top

Protein Sequence Length: 409 aa Download sequence Send to blast

MLFCFELDYL QASFAGLDYS LDHHLHQPPQ HHELMKPRIA ETSGDDDSNT GMIYYMLNNP  60
HQPQMSPGFC TSTSFDKLSF ADVMQFADFG PKLALNQTKI SEEEIGIDPV YFLKFPVLNE  120
KIEEQSLMVP QLGGENDERF TGVSSDEHRE GMVGEEGGVR EDEEARLWDN NSVQLQFLGD  180
QDLQNKNPIP EGKNKRKRPR TIKTSEEVES QRMTHIAVER NRRKQMNEHL RVLRSFMPGS  240
YVQRGDQASI IGGAIVFVRE LEQLLQCLES QKRQRLMEDS ALAIQQPHRP FFPPMPQPND  300
QMKTLDLETE LREETAENKS CLADVEVKLL GFDAMIKILS RRRPGQLIET IAALEDLQLN  360
IHHTSITTIE QTVLYSFNAK IESESRFTAE DIASSVQHAF TFIHANSSM

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	211	222	RMTHIAVERNRR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator (PubMed:17088607, PubMed:17183265, PubMed:17183267). Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata (PubMed:17088607, PubMed:17183265, PubMed:17183267). Prevents histone H3K27me3 marks and derepresses stem cell gene expression (PubMed:24654956). {ECO:0000269\|PubMed:17088607, ECO:0000269\|PubMed:17183265, ECO:0000269\|PubMed:17183267, ECO:0000269\|PubMed:24571519, ECO:0000269\|PubMed:24654956}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Inhibited by low relative humidity (LRH) via epigenetic CG methylation, thus leading to a reduced stomatal index. {ECO:0000269\|PubMed:22442411}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011041873.1	0.0	PREDICTED: transcription factor FAMA-like isoform X1
Swissprot	Q56YJ8	1e-139	FAMA_ARATH; Transcription factor FAMA
TrEMBL	A0A2K1X3M0	0.0	A0A2K1X3M0_POPTR; Uncharacterized protein
STRING	POPTR_0001s32160.1	0.0	(Populus trichocarpa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF10489	33	40

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G24140.1	1e-123	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Matos JL, et al. Irreversible fate commitment in the Arabidopsis stomatal lineage requires a FAMA and RETINOBLASTOMA-RELATED module. Elife, 2015. [PMID:25303364] Chen L, et al. NRPB3, the third largest subunit of RNA polymerase II, is essential for stomatal patterning and differentiation in Arabidopsis. Development, 2016. 143(9): p. 1600-11 [PMID:26989174] Lee JH,Jung JH,Park CM Light Inhibits COP1-Mediated Degradation of ICE Transcription Factors to Induce Stomatal Development in Arabidopsis. Plant Cell, 2017. 29(11): p. 2817-2830 [PMID:29070509] Han X, et al. Jasmonate Negatively Regulates Stomatal Development in Arabidopsis Cotyledons. Plant Physiol., 2018. 176(4): p. 2871-2885 [PMID:29496884] Li X,Yang R,Chen H The Arabidopsis thaliana Mediator subunit MED8 regulates plant immunity to Botrytis Cinerea through interacting with the basic helix-loop-helix (bHLH) transcription factor FAMA. PLoS ONE, 2018. 13(3): p. e0193458 [PMID:29513733]