PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Brast09G075600.4.p

Organism

Brachypodium stacei

Taxonomic ID

1071399

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Brachypodieae; Brachypodium

Family

E2F/DP

Protein Properties

Length: 337aa MW: 37215.8 Da PI: 4.3934

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Brast09G075600.4.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	86.1	2.6e-27	25	90	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++ll+++e+giv+ln++a+ L dv ++RRiYDi+NVLe+++liekk kn+i+wkg Brast09G075600.4.p 25 RYDNSLGLLTRKFINLLKQAEDGIVDLNSAAEIL---DV--QKRRIYDITNVLEGIGLIEKKIKNRIHWKG 90 689*****************************.....****************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.8E-28	22	92	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	5.03E-18	25	88	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	7.7E-35	25	90	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	6.1E-24	27	90	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	1.54E-41	100	206	No hit	No description
SuperFamily	SSF144074	7.85E-30	102	206	No hit	No description
Pfam	PF16421	5.8E-29	105	204	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 337 aa Download sequence Send to blast
MVELHAPLCF AGSPGNPLTP AGSCRYDNSL GLLTRKFINL LKQAEDGIVD LNSAAEILDV 60 QKRRIYDITN VLEGIGLIEK KIKNRIHWKG LNDSGSNSDN TISVLQTEVE NLNLQEEVLD 120 EHISEIHEKI REFTEEESNQ RWLYLTEDDI KGLPCFQNGT LIAIKAPHGT TLEVPDPDEA 180 GDYIKRMYRI VIRSTRGSID LYLVSKSDEK IEEVDVATPP RQADLATPTS VKGFGAIEAG 240 QSSRANDMLP NIQYIRKTPD LNAQDFGGVA ITPEVDTDAD YWLLTDGDDV SITDMWKTAP 300 EVQWDQFLAK EETTPCALKQ QAAVVGKPTV VGPTHG*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	4e-24	20	92	2	75	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Brast09G075600.4.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003581217.1	0.0	transcription factor E2FA isoform X1
Swissprot	Q9FNY0	2e-98	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A0Q3E402	0.0	A0A0Q3E402_BRADI; Uncharacterized protein
STRING	Traes_2DL_BD8048C15.1	1e-176	(Triticum aestivum)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	2e-93	E2F transcription factor 3

Link Out ? help Back to Top
Phytozome	Brast09G075600.4.p

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]