PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Brast09G075600.3.p
Organism
Brachypodium stacei
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Brachypodieae; Brachypodium
Family E2F/DP
Protein Properties Length: 355aa    MW: 38998.8 Da    PI: 4.691
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Brast09G075600.3.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP862.9e-2744109171
             E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                         r+++sL+llt+kf++ll+++e+giv+ln++a+ L   dv  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Brast09G075600.3.p  44 RYDNSLGLLTRKFINLLKQAEDGIVDLNSAAEIL---DV--QKRRIYDITNVLEGIGLIEKKIKNRIHWKG 109
                         689*******************************...**..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.9E-2841111IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013727.7E-3544109IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467855.44E-1844107IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023196.6E-2446109IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.14E-41119225No hitNo description
SuperFamilySSF1440748.63E-30121225No hitNo description
PfamPF164216.4E-29124223IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 355 aa     Download sequence    Send to blast
MTPVSGKASR TYKSKAKCSK SGPQTPISNA GSPGNPLTPA GSCRYDNSLG LLTRKFINLL  60
KQAEDGIVDL NSAAEILDVQ KRRIYDITNV LEGIGLIEKK IKNRIHWKGL NDSGSNSDNT  120
ISVLQTEVEN LNLQEEVLDE HISEIHEKIR EFTEEESNQR WLYLTEDDIK GLPCFQNGTL  180
IAIKAPHGTT LEVPDPDEAG DYIKRMYRIV IRSTRGSIDL YLVSKSDEKI EEVDVATPPR  240
QADLATPTSV KGFGAIEAGQ SSRANDMLPN IQYIRKTPDL NAQDFGGVAI TPEVDTDADY  300
WLLTDGDDVS ITDMWKTAQV QWDQFLAKEE TTPCALKQQA AVVGKPTVVG PTHG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A5e-2439111275PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapBrast09G075600.3.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003581217.10.0transcription factor E2FA isoform X1
SwissprotQ9FNY01e-106E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A0Q3E4020.0A0A0Q3E402_BRADI; Uncharacterized protein
STRINGTraes_2DL_BD8048C15.10.0(Triticum aestivum)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-100E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]