PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Bostr.9345s0060.1.p
Organism
Boechera stricta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Boechereae; Boechera
Family WRKY
Protein Properties Length: 339aa    MW: 37939 Da    PI: 6.5028
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Bostr.9345s0060.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY79.82.9e-25151211259
                          --SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSSTTEEEEEEES--SS- CS
                 WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedpkvveitYegeHnhe 59 
                          +D y+WrKYGqKe+ +++fprsY+rCt++   gC+++k v+++++dp+ ++itY g H+++
  Bostr.9345s0060.1.p 151 EDRYAWRKYGQKEILNATFPRSYFRCTHKptqGCQATKLVQKQEQDPEKFQITYIGYHTCT 211
                          7***************************9999***************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.802.3E-24138211IPR003657WRKY domain
SuperFamilySSF1182904.71E-23144211IPR003657WRKY domain
PROSITE profilePS5081119.566145213IPR003657WRKY domain
SMARTSM007743.9E-34150212IPR003657WRKY domain
PfamPF031068.0E-24151210IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009751Biological Processresponse to salicylic acid
GO:0031347Biological Processregulation of defense response
GO:1900056Biological Processnegative regulation of leaf senescence
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 339 aa     Download sequence    Send to blast
MDSNSNNTKS IKRKVVDQLV EGYEFATQLQ LLLSHQHSNH HIDQTRLVSR SSSVSGVPDP  60
VDELLAKILG SFHKTISVLD TFDPVAVSVP IAVEGSWNAS CGDDSVAPAS CNGGDSGDSK  120
RKRLGVGKGK RGCYTRKKRS HTRIVEARSS EDRYAWRKYG QKEILNATFP RSYFRCTHKP  180
TQGCQATKLV QKQEQDPEKF QITYIGYHTC TANDQIHAKV EPIDHEIIMD SDKTLAATTA  240
QNHVNAKIQE QENNISSVTV VSTVKEGENN NGDLCKEYCE GSSTDGDLSL VWQEMMMFYD  300
HQQHHQNQYY CGEISTTSHH FAFIDDDQFS SFFDPYCA*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6ir8_A1e-17145210368OsWRKY45
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1120138RKRLGVGKGKRGCYTRKKR
2136140KKRSH
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Together with WRKY70, negative regulator of developmental senescence, probably via the regulation of several senescence-associated markers genes (PubMed:22268143). Positive regulator of EDS1-dependent defense against E.amylovora (PubMed:22316300). In collaboration with WRKY70, prevents stomatal closure and, consequently, osmotic stress tolerance (PubMed:23815736). Together with WRKY46 and WRKY70, promotes brassinosteroid (BR)-regulated plant growth but prevent drought response by modulating gene expression (PubMed:28576847). Negative regulator of SA biosynthesis (PubMed:28837631). Prevents defense response to the necrotrophic pathogens P.carotovorum and B.cinerea, but promotes defense against biotrophic/hemibiotrophic pathogens P.syringae pv. tomato (Pst) DC3000, probably by regulating negatively the jasmonic acid (JA)/ethylene (ET) and positively the salicylic acid (SA) signaling pathways (PubMed:28837631). {ECO:0000250|UniProtKB:Q9SUP6, ECO:0000269|PubMed:22268143, ECO:0000269|PubMed:22316300, ECO:0000269|PubMed:23815736, ECO:0000269|PubMed:28576847, ECO:0000269|PubMed:28837631, ECO:0000303|PubMed:28837631}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapBostr.9345s0060.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by reactive oxygen species (ROS) and salicylic acid (SA) (PubMed:22268143). Early but transient accumulation after osmotic stress (e.g. polyethylene glycol, PEG) (PubMed:23815736). Up-regulated by E.amylovora (PubMed:22316300). {ECO:0000269|PubMed:22268143, ECO:0000269|PubMed:22316300, ECO:0000269|PubMed:23815736}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF4262530.0AF426253.1 Arabidopsis thaliana WRKY transcription factor 54 (WRKY54) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010517514.10.0PREDICTED: probable WRKY transcription factor 54
SwissprotQ93WU80.0WRK54_ARATH; Probable WRKY transcription factor 54
TrEMBLD7LFT90.0D7LFT9_ARALL; Predicted protein
STRINGBostr.9345s0060.1.p0.0(Boechera stricta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM113621631
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G40750.11e-158WRKY DNA-binding protein 54
Publications ? help Back to Top
  1. Wang Y,Joshi T,Zhang XS,Xu D,Chen L
    Inferring gene regulatory networks from multiple microarray datasets.
    Bioinformatics, 2006. 22(19): p. 2413-20
    [PMID:16864593]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Lee MH,Jeon HS,Kim HG,Park OK
    An Arabidopsis NAC transcription factor NAC4 promotes pathogen-induced cell death under negative regulation by microRNA164.
    New Phytol., 2017. 214(1): p. 343-360
    [PMID:28032643]
  4. Timmermann T, et al.
    Paraburkholderia phytofirmans PsJN Protects Arabidopsis thaliana Against a Virulent Strain of Pseudomonas syringae Through the Activation of Induced Resistance.
    Mol. Plant Microbe Interact., 2017. 30(3): p. 215-230
    [PMID:28118091]
  5. Chen J, et al.
    Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses.
    Plant Cell, 2017. 29(6): p. 1425-1439
    [PMID:28576847]
  6. Li J,Zhong R,Palva ET
    WRKY70 and its homolog WRKY54 negatively modulate the cell wall-associated defenses to necrotrophic pathogens in Arabidopsis.
    PLoS ONE, 2017. 12(8): p. e0183731
    [PMID:28837631]