PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Boechereae; Boechera

Family

bHLH

Protein Properties

Length: 296aa MW: 33606.6 Da PI: 5.7474

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Bostr.19427s0043.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	33	1.1e-10	119	165	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 h +Er+RR+++ ++f L llP + kK +K++iL A+ +k+Lq Bostr.19427s0043.1.p 119 EHVLAERKRREKLSEKFIALSALLPGL-----KKADKVTILDDAISRMKQLQ 165 5899*********************.....9****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	14.615	115	164	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.0E-16	119	180	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.4E-8	119	165	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	7.10E-10	120	167	No hit	No description
SuperFamily	SSF47459	1.96E-15	120	179	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.2E-12	121	170	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 296 aa Download sequence Send to blast
MEEDFTLTDF SLEDIDFDFN FYEENNLSAD EADMDSQRAQ RSSHLDHQML LEFLGEKPKS 60 AVKPMMKINN NPRLISFDFS SNVSSSPAVE EIIMDKLVGR GTKRKTCSHG TRSPVLAKEH 120 VLAERKRREK LSEKFIALSA LLPGLKKADK VTILDDAISR MKQLQEQMRK LKEEKEATRE 180 VESIILVKRS KVLFDEEPNL SSCPSDHNQF DQALPEIEAK VSQNDVLIRI HCEKSKGCMI 240 NILNTIEKLQ LRIQNSIVLP FGDSTLDITV LAQMDKDFSV SVLKELVRNL RVAVV*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	123	128	ERKRRE
2	124	129	RKRREK

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Bostr.19427s0043.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cold treatment. {ECO:0000269\|PubMed:12679534}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	DQ446550	0.0	DQ446550.1 Arabidopsis thaliana clone pENTR221-At2g22760 basic helix-loop-helix family protein (At2g22760) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010472272.1	0.0	PREDICTED: transcription factor bHLH19-like isoform X1
Swissprot	Q1PF16	1e-177	BH019_ARATH; Transcription factor bHLH19
TrEMBL	C0SV56	1e-175	C0SV56_ARATH; Uncharacterized protein At2g22760 (Fragment)
STRING	Bostr.19427s0043.1.p	0.0	(Boechera stricta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM492	27	146

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22760.1	1e-171	bHLH family protein

Link Out ? help Back to Top
Phytozome	Bostr.19427s0043.1.p

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]