PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Boechereae; Boechera

Family

bHLH

Protein Properties

Length: 282aa MW: 31934.5 Da PI: 4.4976

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Bostr.0597s0053.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	31.2	3.9e-10	132	179	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rEr RR+++N++f L ++l + + +K +K +iL A++ +++L Bostr.0597s0053.1.p 132 TKACRERLRREKLNERFTDLSSVLEPG---RTPKTDKPAILDDAIRILNQL 179 6789********************8...8**************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	9.55E-13	123	193	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	13.23	128	179	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.9E-7	132	179	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.10E-7	132	182	No hit	No description
SMART	SM00353	4.4E-9	134	185	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.2E-11	134	201	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 282 aa Download sequence Send to blast
MYPSLDEDFV SDLFCFDQSN GAELDDYTQF GVNLQPDQED TFPDFGSYGV DLQQEPEEVF 60 SIAGQLDLAS YSGVLTQEPQ QVGQKDCRVV QEEEVEINSG SSGGAVKQEQ EHLDEDYSRK 120 RARTGSCSRG GTKACRERLR REKLNERFTD LSSVLEPGRT PKTDKPAILD DAIRILNQLR 180 DEAHKLEETN QKLLDEIKSL KAEKNELREE KLVLKADKEK TEQQLKSMVV PSSGFMPQIP 240 AAFNHNKMAV YPSYGYMPMW HYMPQSVRDT SRDQELRPPA A*

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00102	PBM	Transfer from AT4G14410	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Bostr.0597s0053.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY088053	0.0	AY088053.1 Arabidopsis thaliana clone 40736 mRNA, complete sequence.
GenBank	AY102106	0.0	AY102106.1 Arabidopsis thaliana AT4g14410/dl3245w mRNA, complete cds.
GenBank	AY133565	0.0	AY133565.1 Arabidopsis thaliana At4g14410/dl3245w mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006284189.2	0.0	transcription factor bHLH104
Swissprot	Q8L467	0.0	BH104_ARATH; Transcription factor bHLH104
TrEMBL	R0F5N0	0.0	R0F5N0_9BRAS; Uncharacterized protein (Fragment)
STRING	Bostr.0597s0053.1.p	0.0	(Boechera stricta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4026	26	53

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G14410.1	1e-175	bHLH family protein

Link Out ? help Back to Top
Phytozome	Bostr.0597s0053.1.p

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Wang C,Yao X,Yu D,Liang G Fe-deficiency-induced expression of bHLH104 enhances Fe-deficiency tolerance of Arabidopsis thaliana. Planta, 2017. 246(3): p. 421-431 [PMID:28451750] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Min JH, et al. A basic helix-loop-helix 104 (bHLH104) protein functions as a transcriptional repressor for glucose and abscisic acid signaling in Arabidopsis. Plant Physiol. Biochem., 2019. 136: p. 34-42 [PMID:30639920]