PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa

Family

bHLH

Protein Properties

Length: 548aa MW: 59798.9 Da PI: 4.9576

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
BGIOSGA014567-PA	genome	RIS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	40.6	4.5e-13	372	418	3	54
HHHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 ++h + ErrRR+++N+ f L++++P+ K++Ka+iLe+++ Y+k L BGIOSGA014567-PA 372 KNHVISERRRREKLNEMFLILKSIVPSiH------KVDKASILEETIAYLKVL 418 57999********************66......*************977 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	2.2E-46	21	197	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	15.834	369	418	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	6.17E-15	372	423	No hit	No description
SuperFamily	SSF47459	1.57E-17	372	439	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.6E-10	373	418	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	8.6E-16	373	436	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.6E-14	375	424	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010026	Biological Process	trichome differentiation
GO:0010214	Biological Process	seed coat development
GO:2000029	Biological Process	regulation of proanthocyanidin biosynthetic process
GO:0000976	Molecular Function	transcription regulatory region sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 548 aa Download sequence Send to blast
MASAPPVQEE ALQPGTNHFR SLLAAAVRSI SWSYAIFWSI SNSCPGVLTW NDGFYNGVVK 60 TRKISNSADL TAGQLVVQRS EQLRELYYSL LSGECDHRAR RPIAALSPED LADTEWYYVV 120 CMTYSFQPGQ GLPGKSYASN ASVWLRNAQS ADSKTFLRSL LAKTIICIPF TSGVLELGTT 180 DPVLEDPNLV NRIVAYFQEL QFPICLEVLM STSPSPNETE DADIVSEGLI THNAIEEGQM 240 VVSDECVSNA NRDPITMEID ELYSIYEDLD LDTVRFLEDN GWPVNPSSFQ LVSASSTEAV 300 AAAAAANDVD GVANSQVSCF MAWKSAKSNE MAVPVVTGIE SQKLLKKVVD CGARMSTGRG 360 SRAALTQESG IKNHVISERR RREKLNEMFL ILKSIVPSIH KVDKASILEE TIAYLKVLEK 420 RVKELESSSE PSHQRATETG QQRRCEITGK ELVSEIGVSG GGDAGREHHH VNVTVTDKVV 480 LLEVQCRWKE LVMTRVFDAI KSLCLDVLSV QASAPDGLLG LKIQAKFACS GSVAPGMISE 540 ALQKAIGG

Sequence ? help Back to Top

Protein Sequence Length: 548 aa Download sequence Send to blast

MASAPPVQEE ALQPGTNHFR SLLAAAVRSI SWSYAIFWSI SNSCPGVLTW NDGFYNGVVK  60
TRKISNSADL TAGQLVVQRS EQLRELYYSL LSGECDHRAR RPIAALSPED LADTEWYYVV  120
CMTYSFQPGQ GLPGKSYASN ASVWLRNAQS ADSKTFLRSL LAKTIICIPF TSGVLELGTT  180
DPVLEDPNLV NRIVAYFQEL QFPICLEVLM STSPSPNETE DADIVSEGLI THNAIEEGQM  240
VVSDECVSNA NRDPITMEID ELYSIYEDLD LDTVRFLEDN GWPVNPSSFQ LVSASSTEAV  300
AAAAAANDVD GVANSQVSCF MAWKSAKSNE MAVPVVTGIE SQKLLKKVVD CGARMSTGRG  360
SRAALTQESG IKNHVISERR RREKLNEMFL ILKSIVPSIH KVDKASILEE TIAYLKVLEK  420
RVKELESSSE PSHQRATETG QQRRCEITGK ELVSEIGVSG GGDAGREHHH VNVTVTDKVV  480
LLEVQCRWKE LVMTRVFDAI KSLCLDVLSV QASAPDGLLG LKIQAKFACS GSVAPGMISE  540
ALQKAIGG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	2e-18	5	197	2	192	Transcription factor MYC3
4rqw_B	2e-18	5	197	2	192	Transcription factor MYC3
4rs9_A	2e-18	5	197	2	192	Transcription factor MYC3
4yz6_A	2e-18	5	197	2	192	Transcription factor MYC3
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	377	382	ERRRRE
2	378	383	RRRREK

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Os.49810	0.0	flower

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	37988367	0.0

Functional Description ? help Back to Top
Source	Description
UniProt	Putative transcriptional activator. Control tissue-specific synthesis of anthocyanin pigments in various parts of the maize plant.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK111704	0.0	AK111704.1 Oryza sativa Japonica Group cDNA clone:J023013E24, full insert sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015635094.1	0.0	anthocyanin regulatory R-S protein
Swissprot	P13027	1e-172	ARRS_MAIZE; Anthocyanin regulatory R-S protein
TrEMBL	B8ASW3	0.0	B8ASW3_ORYSI; Uncharacterized protein
STRING	ONIVA04G19650.1	0.0	(Oryza nivara)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP932	33	109

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G09820.1	9e-80	bHLH family protein

Publications ? help Back to Top
Pattanaik S,Xie CH,Yuan L The interaction domains of the plant Myc-like bHLH transcription factors can regulate the transactivation strength. Planta, 2008. 227(3): p. 707-15 [PMID:18075757] Huang ZA, et al. The upregulation of NtAN2 expression at low temperature is required for anthocyanin accumulation in juvenile leaves of Lc-transgenic tobacco (Nicotiana tabacum L.). J Genet Genomics, 2012. 39(3): p. 149-56 [PMID:22464474] Perrot GH,Cone KC Nucleotide sequence of the maize R-S gene. Nucleic Acids Res., 1989. 17(19): p. 8003 [PMID:2798145] Li P, et al. Combined bulked segregant sequencing and traditional linkage analysis for identification of candidate gene for purple leaf sheath in maize. PLoS ONE, 2018. 13(1): p. e0190670 [PMID:29304111]