PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Ranunculales; Ranunculaceae; Thalictroideae; Aquilegia

Family

C2H2

Protein Properties

Length: 467aa MW: 51576.9 Da PI: 9.6075

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Aqcoe4G076700.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	15.7	4.2e-05	59	79	3	23
ETTTTEEESSHHHHHHHHHHT CS zf-C2H2 3 CpdCgksFsrksnLkrHirtH 23 C++Cgk F r nL+ H r H Aqcoe4G076700.1.p 59 CEICGKGFQRDQNLQLHRRGH 79 *******************88 PP
2	zf-C2H2	13.5	0.00021	133	155	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k++ +s+ k H +t+ Aqcoe4G076700.1.p 133 WKCEKCSKRYAVQSDWKAHSKTC 155 58*****************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	4.0E-5	56	79	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.08E-6	56	79	No hit	No description
PROSITE profile	PS50157	11.489	57	79	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.076	57	79	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	59	79	IPR007087	Zinc finger, C2H2
SMART	SM00355	260	98	128	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.5E-4	121	154	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.08E-6	128	153	No hit	No description
SMART	SM00355	130	133	153	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005634	Cellular Component	nucleus
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 467 aa Download sequence Send to blast
MLKNMAGEAI PNVFTQNPIV GSNPPITKKK RNLPGNPDPE AEVIALSPKT LMATNRFLCE 60 ICGKGFQRDQ NLQLHRRGHN LPWKLRQRSS KEPKKRVYVC PEKSCVHNHP SRALGDLTGI 120 KKHFCRKHGE KKWKCEKCSK RYAVQSDWKA HSKTCGTREY RCDCGTLFSR RDSFITHRAF 180 CDALAEETAR VTAASNISNT MATGNLNYHL MGTSHGSSMV QHFSSIFKPI PSNNETVDQT 240 SRSGLSLWRD IQDSQGGNPI NNNIQELHQM GSGGSVTLYS DPFSSGSNPQ QSDQMSWVFG 300 SNKLSSPSVG ELTSSTSLPI GTIKDVPSPH LVSAPSLFST QHQQHQYLSS ASMSATALLQ 360 KAAQMGATST DPLFHGGNGV KSNNNYVQDG NKYNALFGTN PTSNIVRNNQ ENLVADELSS 420 WNQMQMYHPA KRSRIQKDDR TEGEQTRDFL GVGVQTICPS SMNGWM*

Sequence ? help Back to Top

Protein Sequence Length: 467 aa Download sequence Send to blast

MLKNMAGEAI PNVFTQNPIV GSNPPITKKK RNLPGNPDPE AEVIALSPKT LMATNRFLCE  60
ICGKGFQRDQ NLQLHRRGHN LPWKLRQRSS KEPKKRVYVC PEKSCVHNHP SRALGDLTGI  120
KKHFCRKHGE KKWKCEKCSK RYAVQSDWKA HSKTCGTREY RCDCGTLFSR RDSFITHRAF  180
CDALAEETAR VTAASNISNT MATGNLNYHL MGTSHGSSMV QHFSSIFKPI PSNNETVDQT  240
SRSGLSLWRD IQDSQGGNPI NNNIQELHQM GSGGSVTLYS DPFSSGSNPQ QSDQMSWVFG  300
SNKLSSPSVG ELTSSTSLPI GTIKDVPSPH LVSAPSLFST QHQQHQYLSS ASMSATALLQ  360
KAAQMGATST DPLFHGGNGV KSNNNYVQDG NKYNALFGTN PTSNIVRNNQ ENLVADELSS  420
WNQMQMYHPA KRSRIQKDDR TEGEQTRDFL GVGVQTICPS SMNGWM*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	5e-37	129	196	3	70	Zinc finger protein JACKDAW
5b3h_F	5e-37	129	196	3	70	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269\|PubMed:17785527, ECO:0000269\|PubMed:21935722, ECO:0000269\|PubMed:24821766, ECO:0000269\|PubMed:25829440}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00125	DAP	Transfer from AT1G03840	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269\|PubMed:21935722}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010245572.1	0.0	PREDICTED: zinc finger protein MAGPIE-like
Swissprot	Q9ZWA6	1e-151	IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBL	A0A2G5CJ07	0.0	A0A2G5CJ07_AQUCA; Uncharacterized protein
STRING	Aquca_051_00042.1	0.0	(Aquilegia coerulea)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G03840.1	1e-147	C2H2 family protein

Link Out ? help Back to Top
Phytozome	Aqcoe4G076700.1.p

Publications ? help Back to Top
Muñoz-Strale D,León G Identification of two highly specific pollen promoters using transcriptomic data. Plant Physiol. Biochem., 2014. 83: p. 292-9 [PMID:25208507] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]