PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Ranunculales; Ranunculaceae; Thalictroideae; Aquilegia

Family

C2H2

Protein Properties

Length: 549aa MW: 59102.8 Da PI: 8.6182

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Aqcoe3G427600.3.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.3	2.8e-05	6	28	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C+ C+k F r nL+ H r H Aqcoe3G427600.3.p 6 FICEVCNKGFQREQNLQLHRRGH 28 89*******************88 PP
2	zf-C2H2	12.6	0.00041	82	104	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k++ +s+ k H +t+ Aqcoe3G427600.3.p 82 WKCDKCSKRYAVQSDWKAHSKTC 104 58*****************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	6.0E-6	5	28	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	3.61E-7	5	28	No hit	No description
Pfam	PF12171	2.7E-5	6	28	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE profile	PS50157	10.99	6	28	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0052	6	28	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	8	28	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	2.7E-4	70	103	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	3.61E-7	77	102	No hit	No description
SMART	SM00355	140	82	102	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 549 aa Download sequence Send to blast
MATNRFICEV CNKGFQREQN LQLHRRGHNL PWKLKQKTTK EVKRKVYLCP EPTCVHHDPS 60 RALGDLTGIK KHFCRKHGEK KWKCDKCSKR YAVQSDWKAH SKTCGTREYR CDCGTLFSRR 120 DSFITHRAFC DALAQESARL PTGLNTMGSH LYGGSNMGLN LSQVGSQMSS LQDQNHTSND 180 ILRLGGAGAQ YDHLISPSNS SFRPPQPSPA SAFYLPSGSN QDYHEDSQSH HQLLQNKNFH 240 GLMQLPELQS NANNSSPAAA AAAANLFNLS FFSNSSTTSN MNNSSNANNN NSNNHLSSSG 300 LLMPDQFNSG NAGGEGTTLF SGNIMGDHMG NNVSSLYNTS VQSDNVLPQM SATALLQKAA 360 QMGSSTSGNS STLLRGFGSS SSSNARSDRP HMSANFRGSF SSGGGGGGEN LRSQMENDNH 420 LQDIMNNFAN GGSQIFGSGS NSFGASGGHG QETSYAGFNS NRLSLDQQHG NSNMSNMDEA 480 KMHQNQLSAS LGGSDRLTRD FLGVGGMVRS VSGGISQREQ HHGLDISSLD SEIKSATENR 540 SFGSGSLQ*

Sequence ? help Back to Top

Protein Sequence Length: 549 aa Download sequence Send to blast

MATNRFICEV CNKGFQREQN LQLHRRGHNL PWKLKQKTTK EVKRKVYLCP EPTCVHHDPS  60
RALGDLTGIK KHFCRKHGEK KWKCDKCSKR YAVQSDWKAH SKTCGTREYR CDCGTLFSRR  120
DSFITHRAFC DALAQESARL PTGLNTMGSH LYGGSNMGLN LSQVGSQMSS LQDQNHTSND  180
ILRLGGAGAQ YDHLISPSNS SFRPPQPSPA SAFYLPSGSN QDYHEDSQSH HQLLQNKNFH  240
GLMQLPELQS NANNSSPAAA AAAANLFNLS FFSNSSTTSN MNNSSNANNN NSNNHLSSSG  300
LLMPDQFNSG NAGGEGTTLF SGNIMGDHMG NNVSSLYNTS VQSDNVLPQM SATALLQKAA  360
QMGSSTSGNS STLLRGFGSS SSSNARSDRP HMSANFRGSF SSGGGGGGEN LRSQMENDNH  420
LQDIMNNFAN GGSQIFGSGS NSFGASGGHG QETSYAGFNS NRLSLDQQHG NSNMSNMDEA  480
KMHQNQLSAS LGGSDRLTRD FLGVGGMVRS VSGGISQREQ HHGLDISSLD SEIKSATENR  540
SFGSGSLQ*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	2e-33	78	142	3	67	Zinc finger protein JACKDAW
5b3h_F	2e-33	78	142	3	67	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor acting as a positive regulator of the starch synthase SS4. Controls chloroplast development and starch granule formation (PubMed:22898356). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). {ECO:0000269\|PubMed:22898356, ECO:0000269\|PubMed:24821766}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00255	DAP	Transfer from AT2G02070	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC208494	1e-122	AC208494.1 Populus trichocarpa clone JGIACSB265-L05, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010270755.1	0.0	PREDICTED: protein indeterminate-domain 5, chloroplastic-like
Refseq	XP_010270757.1	0.0	PREDICTED: protein indeterminate-domain 5, chloroplastic-like
Swissprot	Q9ZUL3	1e-119	IDD5_ARATH; Protein indeterminate-domain 5, chloroplastic
TrEMBL	A0A2G5F7R0	0.0	A0A2G5F7R0_AQUCA; Uncharacterized protein
STRING	Aquca_002_01389.1	0.0	(Aquilegia coerulea)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G02070.1	1e-102	indeterminate(ID)-domain 5

Link Out ? help Back to Top
Phytozome	Aqcoe3G427600.3.p

Publications ? help Back to Top
Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]